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公开(公告)号：KR101908035B1
公开(公告)日：2018-10-12
申请号：KR1020170046946
申请日：2017-04-11
Applicant: 주식회사 테라시온 바이오메디칼
Inventor： 김은진
CPC classification number: A61M1/0218 , A61M1/0272 , A61M1/3496 , A61M1/3633 , A61M2202/0439 , B01D39/1623 , B01D2239/0492 , B01D2239/10
Abstract: 본발명은백혈구제거용필터및 그제조방법에관한것으로백혈구제거용필터는백혈구를선별적으로필터링하도록마련된섬유필터;를포함하고, 상기섬유필터의표면에는디니트로페닐기가형성될수 있고, 그로인해혈액제제내에포함된백혈구를선별적으로제거할수 있는기술을제공한다. 본발명에의하면, 섬유필터의표면에디니트로페닐기가형성됨에따라, 혈액제제가섬유필터를통과할경우에디니트로페닐기가혈액제제내에존재하는백혈구와결합되며, 혈액제제로부터백혈구를용이하게분리시킬수 있다. 즉, 본발명은백혈구제거시섬유직경의크기에국한받지않으면서도혈액제제성분중 백혈구만을선별적으로제거하는것이가능하다.
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公开(公告)号：KR1020150123780A
公开(公告)日：2015-11-04
申请号：KR1020157014807
申请日：2014-02-13
Applicant: 도레이 카부시키가이샤
IPC: B01D63/02 , A61M1/16 , B01D65/02 , B01D69/08 , B01D71/38 , B01D71/40 , B01D71/44 , B01D71/68 , C08L39/06
CPC classification number: B01D65/022 , A61M1/16 , A61M1/1621 , A61M1/3496 , B01D63/02 , B01D63/021 , B01D67/002 , B01D69/02 , B01D69/08 , B01D69/085 , B01D71/38 , B01D71/40 , B01D71/44 , B01D71/68 , B01D2323/12 , B01D2323/42 , B01D2325/36 , B01D2325/38 , C08L39/06 , C08L41/00
Abstract: (과제) 본발명의과제는혈액적합성이우수하고, 용출물이적은드라이형의중공사막모듈및 상기모듈에내장된중공사막및 중공사막모듈의제조방법을제공하는것이다. (해결수단) 소수성고분자와친수성기함유고분자를함유하는중공사막이내장되고, 이하의항목을만족시키는것을특징으로하는중공사막모듈. (a)상기중공사막의자중에대한함수율이 10중량%이하 (b)상기소수성고분자가질소를함유하지않고, 상기친수성기함유고분자가질소를함유하고, 상기중공사막의질소함유율이 0.05중량%이상 0.4중량%이하 (c)상기막 내표면에있어서의상기친수성기함유고분자의함유율이 20중량%이상 45중량%이하 (d)프라이밍최종유액 10mL중의용출물에대해서적정을위해서사용되는 2.0×10몰/L 과망간산칼륨수용액의소비량이막면적 1㎡당 0.2mL이하
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公开(公告)号：KR101476752B1
公开(公告)日：2014-12-26
申请号：KR1020130064599
申请日：2013-06-05
Applicant: 폴 코포레이션
Inventor： 델지아코제라드알. , 프로비테라팩스톤이.
IPC: A61M1/34
CPC classification number: A61M1/3633 , A61M1/3496 , A61M1/3635 , A61M5/165 , A61M2202/0439
Abstract: 필터및 적어도하나의분산판을포함하는백플러쉬가능한(back-flushable) 필터장치를사용하여 1종이상의목적하는유체성분을수득하는장치, 시스템, 및방법이개시된다.
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公开(公告)号：KR1020130138103A
公开(公告)日：2013-12-18
申请号：KR1020130050707
申请日：2013-05-06
Applicant: 폴 코포레이션
Inventor： 시디퀴임란에이. , 델지아코제라드알. , 프로비테라팩스톤이.
CPC classification number: A61M1/3633 , A61M1/3496 , A61M1/3635 , A61M5/165 , A61M2202/0439
Abstract: Disclosed are a device, a method, and a system for for obtaining more than one biological fluid component using a back-flushable filter device, and reducing the red blood cell contamination. The device includes: a housing which comprises an inflow port and an outflow port, and limits a fluid path in between the inflow port and the outflow port; and a porous fibrous leukocyte removal filter with an upstream surface and a downstream surface, located on the housing after passing through the fluid path.
Abstract translation: 公开了一种用于使用可反冲洗过滤装置获得多于一种生物流体组分并减少红细胞污染的装置，方法和系统。 该装置包括：壳体，其包括流入口和流出口，并且限制流入口和流出口之间的流体路径; 以及具有上游表面和下游表面的多孔纤维白细胞去除过滤器，其通过所述流体路径后位于所述壳体上。
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5.发明公开Plasma gathering method by agglutination of blood cells, and plasma separating apparatus therefor 审中-公开通过血浆细胞分化等离子体分析方法及其等离子体分离装置
公开(公告)号：KR20120072213A
公开(公告)日：2012-07-03
申请号：KR20100134047
申请日：2010-12-23
Applicant: KOREA ELECTRONICS TELECOMM
Inventor： CHOI YO HAN , CHUNG KWANG HYO , SUNG GUN YONG
CPC classification number: G01N33/5094 , G01N33/80 , Y10T436/25125 , A61M1/3472 , A61K2039/505 , A61M1/0209 , A61M1/34 , A61M1/3406 , A61M1/341 , A61M1/3413 , A61M1/3496 , C12M1/12 , C12M1/123
Abstract: PURPOSE: A plasma gathering method and a plasma separating apparatus therefor are provided to improve plasma separation efficiency by inducing blood cohesion. CONSTITUTION: A plasma gathering method comprises an antibody producing step, an antibody complex formation step, a hemagglutination step, and a plasma separation step. In the antibody producing step, an antibody specific to the blood cell(310) of a patient is manufactured. In the antibody complex formation step, an antibody complex(320) is formed by mixing protein and antibody. In the hemagglutination step, blood cells are agglutinated by reacting the antibody complex with target blood. In the plasma separation step, plasma is separated by filtering the target blood.
Abstract translation: 目的：提供等离子体收集方法及其等离子体分离装置，以通过诱导血液凝聚力来提高血浆分离效率。 构成：血浆聚集方法包括抗体产生步骤，抗体复合物形成步骤，凝血步骤和血浆分离步骤。 在抗体制备步骤中，制造对患者的血细胞（310）特异的抗体。 在抗体复合物形成步骤中，通过混合蛋白质和抗体形成抗体复合物（320）。 在血细胞凝集步骤中，血细胞通过使抗体复合物与靶血液反应而凝集。 在血浆分离步骤中，通过过滤靶血来分离血浆。
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Patent Agency Ranking
公开(公告)号：KR1020080091109A
公开(公告)日：2008-10-09
申请号：KR1020087015450
申请日：2007-01-30
Applicant: 테루모 비씨티, 인크.
CPC classification number: A61M1/3496 , A61M1/0209 , A61M1/0218 , A61M1/3633 , A61M1/3672 , A61M1/3693 , A61M1/3696 , A61M1/3698 , A61M1/38 , G01N33/491
Abstract: This invention is directed to a method of collecting and separating whole blood into components. The method includes the steps of adding an anticoagulant having an acidic pH to a bag for collecting and/or separating whole blood, collecting whole blood in the bag, loading the bag containing anticoagulated whole blood on a rotor, spinning the bag on the rotor to separate the whole blood into at least one component; and squeezing the bag on the rotor to push the component from the separation bag into at least one satellite bag.
Abstract translation: 本发明涉及一种收集和分离全血成分的方法。 该方法包括以下步骤：将具有酸性pH的抗凝剂添加到用于收集和/或分离全血的袋中，在袋中收集全血，将含有抗凝血全血的袋装载在转子上，将转子上的袋旋转至 将全血分成至少一个组分; 并将袋子挤压在转子上以将组件从分离袋推入至少一个卫星袋中。
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公开(公告)号：KR101718648B1
公开(公告)日：2017-03-21
申请号：KR1020157025628
申请日：2014-03-18
Applicant: 아사히 가세이 메디컬 가부시키가이샤
Inventor： 아사카와마사후미
CPC classification number: B01D39/163 , A61M1/0281 , A61M1/3496 , A61M1/3633 , A61M2202/0439 , A61M2205/7545 , B01D2239/0627 , B01D2239/1225 , B01D2239/1233
Abstract: 본발명은, 응집물에의한눈막힘을방지하면서, 효율적으로응집물을제거할수 있는응집물제거필터재, 응집물제거방법, 백혈구제거필터및 혈액제제의여과방법을제공한다. 혈액제제중의응집물을제거하기위한응집물제거필터재로서, 섬유길이가 100∼1000 mm이고, 섬도가 0.7∼4.0 dtex인섬유만으로구성되어있고, 평량이 20∼100 g/m임과동시에, 무부하부피밀도가 0.03∼0.10 g/cm이다.
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公开(公告)号：KR1020150141993A
公开(公告)日：2015-12-21
申请号：KR1020157031770
申请日：2014-04-04
Applicant: 프레제니우스 메디칼 케어 도이치란드 게엠베하
Inventor： 켈러,버카드
CPC classification number: G06F19/3406 , A61M1/14 , A61M1/3403 , A61M1/3496 , A61M2205/502 , A61M2205/505 , G06F19/00 , G16H40/63
Abstract: 본발명은의료기기분야에관한것이다. 본발명은의료기기의조작을용이하게하고의료기기를더 안전하게하는목적에근거를두고있다. 그렇게하기위해, 본발명은투명디스플레이가적어도의료기기의일부분의정면에제공될수 있게함으로써의료기기의일부분이투명디스플레이를통해보일수 있고또 조작명령이나메시지와같은정보가투명디스플레이에디스플레이되는방법및 장치를제안한다.
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公开(公告)号：KR1020150013310A
公开(公告)日：2015-02-04
申请号：KR1020147035273
申请日：2010-12-01
Applicant: 엑스테라 메디컬 코퍼레이션
IPC: A61K31/727 , A61K31/70 , A61M1/36
CPC classification number: A61M1/362 , A61K31/60 , A61K31/722 , A61K31/727 , A61K31/728 , A61M1/3472 , A61M1/3496 , A61M1/36 , A61M1/3621 , A61M1/3673 , A61M1/3679 , A61M1/3687 , A61M1/38 , A61M2202/0057
Abstract: 본 발명은 혈액을 헤파린, 헤파란 설페이트 및/또는 제거될 사이토카인 또는 헤파린(흡수질)에 대한 결합 친화도을 갖는 기타 분자 또는 화학 그룹(흡수제 매체 또는 매체)으로 표면 처리된 고체, 기본적으로는 비 마이크로-다공성인 기질과 접촉시킴으로써 혈액 또는 혈청으로부터 사이토카인 및/또는 병원체를 제거하는 방법에 관한 것으로서, 상기 기질 내의 인터스티셜 채널의 크기는, 적당한 흡수 용량을 제공하는 한편 흡수 매체를 통한 혈액이 상대적으로 높은 유동 속도로 흐를 수 있도록, 매체 표면적의 양 및 매체의 결합 자리의 표면 농도와 균형이 맞추어져 있다.
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公开(公告)号：KR1020140108922A
公开(公告)日：2014-09-15
申请号：KR1020130022815
申请日：2013-03-04
Applicant: 주식회사 퓨어멤
CPC classification number: A61M1/3633 , A61M1/3496 , A61M2202/0439 , B01D29/0034 , B01D39/1623
Abstract: The present invention relates to a biocompatible multi-layer filter for removing leukocytes and a method for manufacturing the same and, more specifically, to a biocompatible multi-layer filter for removing leukocytes which comprises a microporous fiber layer, a nanofiber layer, and a coating layer containing in vivo-derived materials or derivatives thereof so as to have excellent leukocyte removal rate and red blood cell recovery rate, and to a method for manufacturing the filter. The biocompatible multi-layer filter for removing leukocytes manufactured by the present invention shows higher leukocyte removal rate and red blood cell recovery rate compared to existing filters for removing leukocytes, and also have excellent biocompatibility, thereby being useful as a blood filter.
Abstract translation: 本发明涉及用于除去白细胞的生物相容性多层过滤器及其制造方法，更具体地，涉及用于除去白细胞的生物相容性多层过滤器，其包含微孔纤维层，纳米纤维层和涂层 含有体内来源的材料或其衍生物的层，以及具有优异的白细胞去除率和红细胞回收率，以及制造该过滤器的方法。 与用于除去白细胞的现有过滤器相比，用于除去本发明制造的白细胞的生物相容性多层过滤器显示出更高的白细胞去除率和红细胞回收率，并且也具有优异的生物相容性，因此可用作血液过滤器。
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