公开(公告)号：US09101617B2

公开(公告)日：2015-08-11

申请号：US12450967

申请日：2008-04-15

申请人： Shunji Uramatsu ,  Akane Kida ,  Hitoshi Shinike ,  Toshinobu Uemura ,  Yoshinobu Fukumori

发明人： Shunji Uramatsu ,  Akane Kida ,  Hitoshi Shinike ,  Toshinobu Uemura ,  Yoshinobu Fukumori

IPC分类号： A61K31/4422 ,  A61K9/14 ,  A61K9/20

CPC分类号： A61K31/4422 ,  A61K9/146 ,  A61K9/2027 ,  A61K9/2095

摘要： The present invention provides a novel base material for a dry solid dispersion, a solid dispersion containing the base material, and a composition containing the dispersion; the solid dispersion of the present invention, which contains a poorly soluble component with improved dissolvability, can be obtained by mixing a polyvinyl alcohol-based copolymer, as a base material for the dry solid dispersion, with a poorly soluble component, and then heating it.

摘要翻译： 本发明提供了一种用于干固体分散体的新型基材，含有该基材的固体分散体和含有该分散体的组合物; 通过将作为干固体分散体的基材的聚乙烯醇类共聚物与难溶性成分混合，然后加热，可以得到含有溶解性提高的难溶性成分的本发明的固体分散体 。

公开(公告)号：US20100120924A1

公开(公告)日：2010-05-13

申请号：US12450967

申请日：2008-04-15

申请人： Shunji Uramatsu ,  Akane Kida ,  Hitoshi Shinike ,  Toshinobu Uemura ,  Yoshinobu Fukumori

发明人： Shunji Uramatsu ,  Akane Kida ,  Hitoshi Shinike ,  Toshinobu Uemura ,  Yoshinobu Fukumori

IPC分类号： A61K47/32 ,  C08F216/06 ,  C08F220/06 ,  C08L29/04

CPC分类号： A61K31/4422 ,  A61K9/146 ,  A61K9/2027 ,  A61K9/2095

摘要： The present invention provides a novel base material for a dry solid dispersion, a solid dispersion containing the base material, and a composition containing the dispersion; the solid dispersion of the present invention, which contains a poorly soluble component with improved dissolvability, can be obtained by mixing a polyvinyl alcohol-based copolymer, as a base material for the dry solid dispersion, with a poorly soluble component, and then heating it.

摘要翻译： 本发明提供了一种用于干固体分散体的新型基材，含有该基材的固体分散体和含有该分散体的组合物; 通过将作为干固体分散体的基材的聚乙烯醇类共聚物与难溶性成分混合，然后加热，可以得到含有溶解性提高的难溶性成分的本发明的固体分散体 。