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    Sustained release tablet
    2.
    发明授权
    Sustained release tablet 失效
    缓释片

    公开(公告)号：US4695467A

    公开(公告)日：1987-09-22

    申请号：US751866

    申请日：1985-07-05

    申请人： Toshinobu Uemura ,  Kiyohide Shinooka ,  Tokuaki Kajiho

    发明人： Toshinobu Uemura ,  Kiyohide Shinooka ,  Tokuaki Kajiho

    IPC分类号： A61K9/20 ,  A61K9/22 ,  A61K9/16

    CPC分类号： A61K9/2095 ,  A61K9/2013 ,  A61K9/2054 ,  Y10S514/96

    摘要： The invention relates to a sustained release tablet which comprises easily disintegrable granules containing(a) a drug,(b) a disintegrating agent selected from the group consisting of starch derivatives, gums, cellulose derivatives and ion-exchange resins, and(c) a water soluble polymer selected from the group consisting of cellulose derivatives, synthetic water soluble polymers and polysaccharides, the surfaces of which granules are treated solely with a wax selected from the group consisting of plant or animal wax, hydrogenated oils and paraffin.

    摘要翻译： 本发明涉及一种缓释片剂，其包含容易崩解的颗粒，其含有（a）药物，（b）选自淀粉衍生物，树胶，纤维素衍生物和离子交换树脂的崩解剂，和（c） 选自纤维素衍生物，合成水溶性聚合物和多糖的水溶性聚合物，其表面仅用选自植物或动物蜡，氢化油和石蜡的蜡进行处理。

    Dry Coating using Twin-Screw Kneader
    4.
    发明申请
    Dry Coating using Twin-Screw Kneader 审中-公开
    使用双螺杆捏合机的干涂层

    公开(公告)号：US20090304800A1

    公开(公告)日：2009-12-10

    申请号：US12083628

    申请日：2006-10-12

    申请人： Shinji Fujimoto ,  Toshinobu Uemura ,  Kantaro Kaneko ,  Yoshinobu Fukumori

    发明人： Shinji Fujimoto ,  Toshinobu Uemura ,  Kantaro Kaneko ,  Yoshinobu Fukumori

    IPC分类号： A61K9/14 ,  B05D3/00

    CPC分类号： A61K9/282 ,  A61K9/2893 ,  A61K9/5015 ,  A61K9/5089 ,  B01J2/006 ,  B01J2/10

    摘要： An object of the present invention is to provide a dry coating process that can produce a dry-coated preparation in a large amount. A large amount of dry-coated preparation can be produced more efficiently, than by prior-art processes, by a process in which a material containing core particles and a dry binder (lauric acid, myristic acid, or the like) is kneaded in a twin-screw kneader to produce dry binder particles in which the surfaces of the core particles are dry-coated with the dry binder. Further, a dry coating particle production process in which a material containing core particles, a dry binder, and a coating powder is kneaded in a twin-screw kneader can also produce a large amount of dry-coated preparation more efficiently than prior-art processes.

    摘要翻译： 本发明的目的是提供能够大量生产干涂层制剂的干式涂布方法。 通过以下方法可以比现有技术方法更有效地生产大量的干涂层制剂：其中将包含芯颗粒和干粘合剂（月桂酸，肉豆蔻酸等）的材料在 双螺杆捏合机以产生干粘合剂颗粒，其中芯颗粒的表面用干粘合剂进行干涂层。 此外，在双螺杆捏和机中捏合含有核颗粒，干粘合剂和涂层粉末的材料的干涂层颗粒生产方法也可以比现有技术的方法更有效地产生大量的干涂布制剂 。