公开(公告)号：US09012172B2

公开(公告)日：2015-04-21

申请号：US13318227

申请日：2010-04-30

申请人： Kevin Kit Parker ,  Adam Walter Feinberg ,  Patrick W. Alford ,  Anna Grosberg ,  Mark D. Brigham ,  Josue Adrian Goss

发明人： Kevin Kit Parker ,  Adam Walter Feinberg ,  Patrick W. Alford ,  Anna Grosberg ,  Mark D. Brigham ,  Josue Adrian Goss

IPC分类号： C12Q1/02 ,  C40B30/06 ,  G01N33/50

CPC分类号： G01N33/5061 ,  C12Q1/025 ,  C40B30/06 ,  G01N33/5032 ,  G01N33/5088 ,  G01N2500/10

摘要： The present invention provides high throughput assays for identifying compounds that modulate a contractile function, as well as devices suitable for use in these assays.

摘要翻译： 本发明提供用于鉴定调节收缩功能的化合物的高通量测定，以及适用于这些测定的装置。

公开(公告)号：US20120142556A1

公开(公告)日：2012-06-07

申请号：US13318227

申请日：2010-04-30

申请人： Kevin Kit Parker ,  Adam Walter Feinberg ,  Patrick W. Alford ,  Anna Grosberg ,  Mark D. Brigham ,  Josue Adrian Goss

发明人： Kevin Kit Parker ,  Adam Walter Feinberg ,  Patrick W. Alford ,  Anna Grosberg ,  Mark D. Brigham ,  Josue Adrian Goss

IPC分类号： C40B30/06 ,  C40B50/06 ,  C40B40/02

CPC分类号： G01N33/5061 ,  C12Q1/025 ,  C40B30/06 ,  G01N33/5032 ,  G01N33/5088 ,  G01N2500/10

摘要： The present invention provides high throughput assays for identifying compounds that modulate a contractile function, as well as devices suitable for use in these assays.

摘要翻译： 本发明提供用于鉴定调节收缩功能的化合物的高通量测定，以及适用于这些测定的装置。

公开(公告)号：US20070208011A1

公开(公告)日：2007-09-06

申请号：US11552589

申请日：2006-10-25

申请人： James Cloyd ,  Ronald Siegel ,  Anna Grosberg ,  Hao Hou

发明人： James Cloyd ,  Ronald Siegel ,  Anna Grosberg ,  Hao Hou

IPC分类号： A61K31/5513

CPC分类号： A61K9/0043

摘要： The invention describes supersaturated solutions of benzodiazepines, such as diazepam, glycofurol and water and their use for intranasal (NS) administration to combat various disorders.

摘要翻译： 本发明描述了苯二氮卓类的过饱和溶液，例如地西泮，糖酵解和水，以及其用于鼻内（NS）给药以对抗各种疾病的用途。

公开(公告)号：US09656009B2

公开(公告)日：2017-05-23

申请号：US12218237

申请日：2008-07-11

申请人： Arash Kheradvar ,  Morteza Gharib ,  Anna Grosberg

发明人： Arash Kheradvar ,  Morteza Gharib ,  Anna Grosberg

IPC分类号： A61N1/362 ,  A61M1/10 ,  A61M1/12 ,  A61N1/365 ,  A61F2/24 ,  A61F2/915 ,  A61N1/36 ,  A61M1/36

CPC分类号： A61M1/1068 ,  A61F2/2478 ,  A61F2/2481 ,  A61F2/915 ,  A61M1/1003 ,  A61M1/1048 ,  A61M1/1049 ,  A61M1/1056 ,  A61M1/1058 ,  A61M1/12 ,  A61M1/122 ,  A61M1/127 ,  A61M1/36 ,  A61M2205/0283 ,  A61N1/36 ,  A61N1/3627 ,  A61N1/36514 ,  A61N1/36521

摘要： A cardiac assist system using a helical arrangement of contractile bands and a helically-twisting cardiac assist device are disclosed. One embodiment discloses a cardiac assist system comprising at least one contractile elastic band helically arrangement around a periphery of a patient's heart, where upon an actuation the band contracts helically, thereby squeezing the heart and assisting the pumping function of the heart. Another embodiment discloses a helically twisting cardiac-apex assist device comprising an open, inverted, substantially conical chamber with two rotatable ring portions of different diameters located at the base and apex of the chamber, with a plurality of substantially helical connecting elements positioned substantially flush with the chamber wall and connecting the two rotatable ring portions, whereby a relative twisting motion of the two rings causes a change in volume of the chamber thereby assisting the cardiac pumping function.