公开(公告)号：US20140217031A1

公开(公告)日：2014-08-07

申请号：US14125957

申请日：2012-06-15

申请人： Ziqiang Wang ,  Steve Zulli ,  Daniel Rolle ,  Chuping Luo ,  Harbaksh Sidhu

发明人： Ziqiang Wang ,  Steve Zulli ,  Daniel Rolle ,  Chuping Luo ,  Harbaksh Sidhu

IPC分类号： B01D15/16

CPC分类号： B01D15/165 ,  B01D15/24 ,  B01D15/247 ,  B01D15/40 ,  G01N30/62 ,  G01N30/80 ,  G01N30/82 ,  G01N2030/027

摘要： A supercritical fluid chromatography system comprises a first pump for pumping a first flow stream comprising a compressible fluid and a second pump for pumping a second flow stream comprising a modifier fluid. The second pump is in parallel with the first pump. A column is located in a combined flow stream. The column is located downstream of the first and second pumps. The combined flow stream comprises the first flow stream, the second flow stream, and a sample. A detector is located downstream of the column. A gas-liquid separator is located downstream of the detector. The gas-liquid separator is configured to vent a majority of the compressible fluid while maintaining a majority of the sample, thus preventing aerosolization of the flow stream and minimizing sample loss as well as cross contamination. An open bed collector is located after the gas-liquid separator.

摘要翻译： 超临界流体色谱系统包括用于泵送包含可压缩流体的第一流动流的第一泵和用于泵送包含改性剂流体的第二流动流的第二泵。 第二个泵与第一个泵并联。 一列位于组合的流动流中。 该柱位于第一和第二泵的下游。 组合的流动流包括第一流动流，第二流动流和样品。 检测器位于柱的下游。 气液分离器位于检测器的下游。 气液分离器被配置为排出大部分可压缩流体，同时保持样品的大部分，从而防止流动物流的雾化，并最小化样品损失以及交叉污染。 开式床收集器位于气液分离器之后。

公开(公告)号：US09731219B2

公开(公告)日：2017-08-15

申请号：US14125957

申请日：2012-06-15

申请人： Ziqiang Wang ,  Steven L. Zulli ,  Daniel Rolle ,  Chuping Luo ,  Harbaksh Sidhu

发明人： Ziqiang Wang ,  Steven L. Zulli ,  Daniel Rolle ,  Chuping Luo ,  Harbaksh Sidhu

IPC分类号： B01D15/40 ,  B01D15/16 ,  B01D15/24 ,  G01N30/80 ,  G01N30/62 ,  G01N30/82 ,  G01N30/02

CPC分类号： B01D15/165 ,  B01D15/24 ,  B01D15/247 ,  B01D15/40 ,  G01N30/62 ,  G01N30/80 ,  G01N30/82 ,  G01N2030/027

摘要： A supercritical fluid chromatography system comprises a first pump for pumping a first flow stream comprising a compressible fluid and a second pump for pumping a second flow stream comprising a modifier fluid. The second pump is in parallel with the first pump. A column is located in a combined flow stream. The column is located downstream of the first and second pumps. The combined flow stream comprises the first flow stream, the second flow stream, and a sample. A detector is located downstream of the column. A gas-liquid separator is located downstream of the detector. The gas-liquid separator is configured to vent a majority of the compressible fluid while maintaining a majority of the sample, thus preventing aerosolization of the flow stream and minimizing sample loss as well as cross contamination. An open bed collector is located after the gas-liquid separator.