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公开(公告)号：US08784864B2
公开(公告)日：2014-07-22
申请号：US13147082
申请日：2010-01-29
CPC分类号： A61F2/30767 , A61F2002/30838 , A61F2002/3084 , A61F2310/00023 , A61F2310/00616 , A61L27/06 , A61L2400/18 , A61L2430/02
摘要： Bone repair materials are disclosed, from which ions are hardly eluted in living body and which are superior in apatite-forming ability and resistance to apatite peeling and have a scratch resistance high enough for practical use. The material comprises a substrate made of titanium or titanium alloys, and a surface layer, made substantially of titanium oxide, along the surface of the substrate. The substrate has on the surface thereof irregularities of from 1 nm to 10 μm in average in both width and depth. The layer has a zeta potential of +4.5 mV or more under an aqueous solution environment of pH 6 to 8, and a critical scratch resistance of 35 mN or more when vibration 100 μm in amplitude is added to a stylus with a spring constant of 200 g/mm on the surface layer and the stylus is moved at a rate of 10 mm/sec under a load increasing at a rate of 100 mN/min.
摘要翻译： 公开了骨修复材料，其中离子几乎不在生物体中洗脱，并且磷灰石形成能力和磷灰石剥离性都优异，并且具有足够高的实用用途的耐擦伤性。 该材料包括由钛或钛合金制成的基材，以及基本上由氧化钛制成的表面层。 基板在表面上的宽度和深度均匀地具有1nm至10μm的不规则性。 在pH6〜8的水溶液环境下，该层的ζ电位为+4.5mV以上，当振幅为100μm的振幅加入弹簧常数为200的触针时，临界耐擦伤性为35mN以上 表面层上的g / mm和触针以10毫米/秒的速率移动，负载以100毫微米/分钟的速率增加。
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公开(公告)号：US20110287070A1
公开(公告)日：2011-11-24
申请号：US13147082
申请日：2010-01-29
CPC分类号： A61F2/30767 , A61F2002/30838 , A61F2002/3084 , A61F2310/00023 , A61F2310/00616 , A61L27/06 , A61L2400/18 , A61L2430/02
摘要： Bone repair materials are disclosed, from which ions are hardly eluted in living body and which are superior in apatite-forming ability and resistance to apatite peeling and have a scratch resistance high enough for practical use. The material comprises a substrate made of titanium or titanium alloys, and a surface layer, made substantially of titanium oxide, along the surface of the substrate. The substrate has on the surface thereof irregularities of from 1 nm to 10 μm in average in both width and depth. The layer has a zeta potential of +4.5 mV or more under an aqueous solution environment of pH 6 to 8, and a critical scratch resistance of 35 mN or more when vibration 100 μm in amplitude is added to a stylus with a spring constant of 200 g/mm on the surface layer and the stylus is moved at a rate of 10 mm/sec under a load increasing at a rate of 100 mN/min.
摘要翻译： 公开了骨修复材料，其中离子几乎不在生物体中洗脱，并且磷灰石形成能力和磷灰石剥离性都优异，并且具有足够高的实用用途的耐擦伤性。 该材料包括由钛或钛合金制成的基材，以及基本上由氧化钛制成的表面层。 基板在表面上的宽度和深度均匀地具有1nm至10μm的不规则性。 在pH6〜8的水溶液环境下，该层的ζ电位为+4.5mV以上，当将振幅为100μm的振幅加到弹簧常数为200的触笔上时，临界耐擦伤性为35mN以上 表面层上的g / mm和触针以10毫米/秒的速率移动，负载以100毫微米/分钟的速率增加。
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