公开(公告)号：US20240350272A1

公开(公告)日：2024-10-24

申请号：US18761853

申请日：2024-07-02

申请人： ALPS HOLDING LLC

发明人： George J. PICHA ,  Grant Wesley PHILLIPS ,  Rachel SMITH ,  James PRICE ,  Gregory CAUSEY

IPC分类号： A61F2/30 ,  A61F2/28 ,  A61F2/38 ,  A61F2/40 ,  A61F2/42 ,  A61F2/44 ,  A61L27/06 ,  A61L27/18

CPC分类号： A61F2/30771 ,  A61F2/3859 ,  A61F2/389 ,  A61F2/4081 ,  A61F2/4202 ,  A61F2/4261 ,  A61F2/442 ,  A61L27/06 ,  A61L27/18 ,  A61F2/2803 ,  A61F2002/30069 ,  A61F2002/30224 ,  A61F2002/30326 ,  A61F2002/30383 ,  A61F2002/30896 ,  A61F2002/3093 ,  A61F2002/3863 ,  A61F2002/4205 ,  A61F2002/4207 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00293 ,  A61F2310/00359 ,  A61L2430/02 ,  A61L2430/38

摘要： Hard-tissue implants are provided that include a bulk implant, a face, pillars, slots, and at least one support member. The pillars are for contacting a hard tissue. The slots are to be occupied by the hard tissue. The at least one support member is for contacting the hard tissue. The hard-tissue implant has a Young's modulus of elasticity of at least 3 GPa, and has a ratio of the sum of (i) the volumes of the slots to (ii) the sum of the volumes of the pillars and the volumes of the slots of 0.40:1 to 0.90:1. Methods of making and using hard-tissue implants are also provided.

公开(公告)号：US12115277B2

公开(公告)日：2024-10-15

申请号：US17053480

申请日：2019-04-30

申请人： Waldemar Link GmbH & Co. KG

发明人： Helmut D. Link ,  Richard Csaszar

IPC分类号： A61L27/30 ,  A61L27/04 ,  A61L27/06 ,  A61L27/10 ,  A61L27/54 ,  C23C14/02 ,  C23C14/06 ,  C23C14/26

CPC分类号： A61L27/306 ,  A61L27/047 ,  A61L27/06 ,  A61L27/10 ,  A61L27/54 ,  C23C14/022 ,  C23C14/0641 ,  C23C14/26 ,  A61L2300/104 ,  A61L2300/404 ,  A61L2300/606 ,  A61L2420/02 ,  A61L2420/06 ,  A61L2430/38

摘要： A coating for an implant component, in particular a component of a spinal implant, is provided. The coating is a ceramic titanium nitride coating comprising an at % content of 5 to 30 At % of Ag in addition to an at % content of Ti and an at % content of N.

公开(公告)号：US12011354B2

公开(公告)日：2024-06-18

申请号：US17936917

申请日：2022-09-30

申请人： WALDEMAR LINK GmbH & Co. KG

发明人： Helmut D. Link

IPC分类号： A61F2/32 ,  A61F2/28 ,  A61F2/30 ,  A61L27/04 ,  A61L27/06 ,  A61L27/30 ,  C23C4/08 ,  C23C4/134

CPC分类号： A61F2/30771 ,  A61L27/042 ,  A61L27/045 ,  A61L27/047 ,  A61L27/06 ,  A61L27/306 ,  A61F2002/3092 ,  A61F2/32 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00101 ,  A61F2310/00544 ,  A61L2420/02 ,  A61L2430/02 ,  C23C4/08 ,  C23C4/134

摘要： The present invention relates to an implant comprising an implant body having a first surface area configured for contact with soft connective tissue and a second surface area configured for contact with bone tissue, wherein the first surface area is covered with a coating comprising tantalum and the second surface area is formed by a material, which is different than the one forming the coating.

公开(公告)号：US20240123495A1

公开(公告)日：2024-04-18

申请号：US18509326

申请日：2023-11-15

申请人： TANIOBIS GMBH

发明人： MARKUS WEINMANN ,  HOLGER BRUMM ,  CHRISTOPH SCHNITTER ,  MELANIE STENZEL

IPC分类号： B22F1/052 ,  A61L27/04 ,  A61L27/06 ,  B22F1/065 ,  B22F9/08 ,  B22F10/25 ,  B22F10/28 ,  B22F10/34 ,  B33Y70/00 ,  C22C14/00

CPC分类号： B22F1/052 ,  A61L27/047 ,  A61L27/06 ,  B22F1/065 ,  B22F9/082 ,  B22F10/25 ,  B22F10/28 ,  B22F10/34 ,  B33Y70/00 ,  C22C14/00 ,  B33Y10/00

摘要： A method of using a metal powder in an additive manufacturing process. The method includes providing the metal powder, and using the metal powder in the additive manufacturing process. The metal powder is a metal which is selected from tantalum and impurities, titanium and impurities, niobium and impurities, an alloy of tantalum, niobium and impurities, an alloy of titanium, niobium and impurities, and an alloy of tantalum, titanium, niobium and impurities. Particles of the metal powder have a dendritic microstructure. Particles of the metal powder have an average aspect ratio ΨA of from 0.7 to 1, where ΨA=XFeret min/XFeret max.

公开(公告)号：US11883560B2

公开(公告)日：2024-01-30

申请号：US17384824

申请日：2021-07-26

申请人： National Taiwan University

发明人： Wei-Hsing Tuan

IPC分类号： A61F2/44 ,  A61L27/38 ,  A61L27/06 ,  A61L27/40 ,  A61L27/56 ,  A61L27/10

CPC分类号： A61L27/3856 ,  A61L27/06 ,  A61L27/105 ,  A61L27/40 ,  A61L27/56 ,  A61L2430/38

摘要： An intervertebral fusion device includes a structural ceramic body. The structural ceramic body has a bottom surface, a top surface, a peripheral surface connected between the bottom surface and the top surface, and at least one pore channel penetrating the bottom surface and the top surface. The inner surface of the pore channel is either a convex curved surface or a funnel-shaped surface. For the pore channel having the convex curved surface, the pore diameter of the pore channel gradually expands from the center of the pore channel to the top surface and the bottom surface. The pore diameter can also gradually expand from the bottom surface to the top surface. The peripheral surface of the structural ceramic body is wavy or zigzag.

公开(公告)号：US20240016978A1

公开(公告)日：2024-01-18

申请号：US18249044

申请日：2021-04-01

申请人： HANGZHOU HUIBO SCIENCE AND TECHNOLOGY CO., LTD

发明人： Gang WU ,  Liyong WU ,  Yunyu LU

IPC分类号： A61L27/32 ,  A61L27/06

CPC分类号： A61L27/32 ,  A61L27/06 ,  A61L2420/02 ,  A61L2430/02

摘要： An efficient biphasic calcium phosphate coating method. A high-concentration (4.5×) supersaturated calcium phosphate solution (SCPS) is used for coating and a thicker continuous coating is formed on a titanium disc. The coating contains dicalcium phosphate dihydrate and hydroxyapatite. The coating has improved encapsulation efficiency of a protein FITC-BSA and releases less Ca2+ under an acidic condition. A more efficient coating with a high yield and a protein encapsulation efficiency can be obtained with a less SCPS solution volume and a shorter coating time, such that a cost is greatly reduced in clinical application and the coating is very expected to be used in an osteogenic implant material in the biomedical field.

公开(公告)号：US11846016B2

公开(公告)日：2023-12-19

申请号：US17543054

申请日：2021-12-06

申请人： Cook Medical Technologies LLC

发明人： John Neilan ,  David Murray ,  James Butler

IPC分类号： A61F2/82 ,  A61L31/02 ,  C23C16/02 ,  A61L31/08 ,  A61L31/16 ,  A61L27/30 ,  A61L27/06 ,  A61L27/54 ,  C23C16/40 ,  C23C16/50 ,  H01J37/32

CPC分类号： C23C16/0227 ,  A61F2/82 ,  A61L27/06 ,  A61L27/306 ,  A61L27/54 ,  A61L31/022 ,  A61L31/088 ,  A61L31/16 ,  C23C16/40 ,  C23C16/50 ,  H01J37/32449 ,  H01J37/32513 ,  A61F2210/0014 ,  A61F2210/0076 ,  A61F2240/001 ,  A61F2250/0067 ,  A61L2300/416 ,  A61L2400/18 ,  A61L2420/02 ,  H01J2237/335 ,  H01J2237/3321

摘要： A method of modifying a surface of a medical device for implantation or disposition inside a patient is described. The medical device comprises a structure having at least one surface. The method includes the steps of: placing the medical device into a plasma chamber substantially free from contaminants and substantially sealing the plasma chamber from the atmosphere; removing at least an outermost layer of any oxide layer from the at least one surface of the structure by a plasma oxide-removal process, whilst maintaining the plasma chamber under seal from the atmosphere; and subsequently forming a new oxide layer at the least one surface of the structure by introducing at least one gas into the plasma chamber, whilst maintaining the plasma chamber under seal from the atmosphere. A medical device including a bulk material and an oxide layer disposed over at least one surface of the medical device. The oxide layer is substantially pure and free from contaminants.

公开(公告)号：US11793907B2

公开(公告)日：2023-10-24

申请号：US17474610

申请日：2021-09-14

申请人： DePuy Synthes Products, Inc.

发明人： Rajendra Kasinath ,  Craig Ernsberger ,  Stephanie Vass ,  Steven N. Ginn ,  Haibo Qu ,  Weidong Tong

IPC分类号： A61L27/12 ,  A61L27/04 ,  A61L27/02 ,  A61L27/06 ,  A61L27/32 ,  A61L27/50 ,  A61L27/56 ,  A61L27/58

CPC分类号： A61L27/12 ,  A61L27/025 ,  A61L27/045 ,  A61L27/047 ,  A61L27/06 ,  A61L27/32 ,  A61L27/50 ,  A61L27/56 ,  A61L27/58

摘要： An orthopedic implant having a metal surface and a hydroxyapatite layer comprising gallium ions therein disposed on at least part of the metal surface is described. The hydroxyapatite layer has an average crystallite size of less than about 75 nm in at least one direction and dissolves for more than 2 hours in vitro. The hydroxyapatite layer is substantially free of carbonate. The coating, which is formed on a sodium titanate surface, has increased shear strength and tensile strength. The coating is formed by a solution deposited hydroxyapatite process under inert conditions. The pH of the solution varies by less than 0.1 pH unit/hour during coating formation.

公开(公告)号：US20230321325A1

公开(公告)日：2023-10-12

申请号：US18336241

申请日：2023-06-16

申请人： Fluid Biomed Inc.

发明人： Alim P. Mitha ,  John H. Wong

IPC分类号： A61L27/58 ,  A61L27/56 ,  A61L27/06 ,  A61L27/04 ,  A61L27/18 ,  A61F2/90 ,  A61F2/07

CPC分类号： A61L27/58 ,  A61L27/56 ,  A61L27/06 ,  A61L27/045 ,  A61L27/18 ,  A61F2/90 ,  A61F2/07 ,  A61F2310/00023 ,  A61F2210/0004 ,  A61F2250/0098 ,  A61F2310/00029

摘要： This disclosure relates to scaffolds made of a braid of bioabsorbable polymeric fibers for implantation within a lumen of a mammalian body and, in particular, to such scaffolds that are configured to divert blood flow from a pathology associated with a blood vessel.

公开(公告)号：US20230301788A1

公开(公告)日：2023-09-28

申请号：US18326753

申请日：2023-05-31

申请人： Titan Spine, Inc.

发明人： Michelle B. Gallagher ,  Mark E. Berg ,  Jennifer M. Schneider

IPC分类号： A61F2/30 ,  A61L27/06 ,  A61L27/50 ,  A61B17/58 ,  A61F2/28

CPC分类号： A61F2/30767 ,  A61L27/06 ,  A61L27/50 ,  A61B17/58 ,  A61F2/2846 ,  A61F2002/30838 ,  A61F2002/3084 ,  A61F2002/3093 ,  A61F2002/30968 ,  A61F2002/3097 ,  A61F2002/30985 ,  A61L2400/18 ,  A61F2/3094

摘要： An orthopedic implant having a titanium or titanium alloy body with a plurality of surfaces. The orthopedic implant is produced according to a process comprising the steps of: (a) additively building the orthopedic implant; and then (b) mechanically, chemically, or mechanically and chemically eroding one or more surfaces of the orthopedic implant to (i) remove alpha case from, and (ii) impart an osteoinducting roughness including micro-scale structures and nano-scale structures into, the one or more surfaces.