公开(公告)号：US20070202151A1

公开(公告)日：2007-08-30

申请号：US11463956

申请日：2006-08-11

申请人： Heejin Lee ,  Karen Daniel ,  Hong Ho Duc ,  Michael Cima ,  Mario Casillo-Ortiz ,  Steven Floelich ,  Jordan Dimitrakov

发明人： Heejin Lee ,  Karen Daniel ,  Hong Ho Duc ,  Michael Cima ,  Mario Casillo-Ortiz ,  Steven Floelich ,  Jordan Dimitrakov

IPC分类号： A61F2/02

CPC分类号： A61M31/002 ,  A61K9/0034 ,  A61L29/06 ,  A61L29/16 ,  A61L2300/402 ,  A61L2300/406 ,  A61L2300/45 ,  A61L2300/63 ,  A61M2202/06 ,  A61M2205/0216 ,  A61M2210/1085 ,  C08L83/04

摘要： Implant devices for intravesical administration and local drug delivery. The device has a body which includes a hollow tube formed of a biocompatible material; at least one reservoir in the tube which contains a drug; and one or more apertures through which the drug can be released. The device is configured for minimally invasive insertion into a body cavity, such as the bladder. The hollow tube may be elastomeric to permit the device to be elastically deformed from its initial shape into an elongated shape for passage through a catheter, where following such passage the device can return to or toward its initial shape to facilitate retention of the device in the body cavity. The body may have a narrow, elongated shape effective to permit insertion of the drug delivery device through a catheter without necessarily deforming the body, yet include flexible projections which effect retention within the body cavity.

摘要翻译： 用于膀胱内给药和局部药物输送的植入装置。 该装置具有包括由生物相容性材料形成的中空管的主体; 管中含有药物的至少一个储存器; 以及可以释放药物的一个或多个孔。 该装置构造成用于微创地插入诸如膀胱的体腔中。 中空管可以是弹性的，以允许该装置从其初始形状弹性变形成细长形状以便通过导管，其中随后通过该装置可以返回或朝向其初始形状，以便于将装置保持在 体腔。 身体可以具有有效的狭窄的细长形状，以允许药物递送装置通过导管插入，而不必使身体变形，而包括有效地保持在体腔内的弹性突起。