公开(公告)号：US12128203B2

公开(公告)日：2024-10-29

申请号：US18202987

申请日：2023-05-29

申请人： PRIMO MEDICAL GROUP, INC.

发明人： Steven J. Tallarida ,  John M. Butziger ,  Richard P. Rodgers

IPC分类号： A61M39/04 ,  A61M39/02 ,  A61M39/00

CPC分类号： A61M39/04 ,  A61M39/0208 ,  A61M2039/0054 ,  A61M2039/0205 ,  A61M2202/06 ,  A61M2205/0205 ,  A61M2205/0216

摘要： A medical device comprising an implantable subcutaneous access port having a septum penetrable by a needle; the septum having a cavity located between an outer wall and an inner wall, the cavity containing a flowable media comprising a plurality of displaceable particles arranged to move in response to the needle being inserted through the outer wall and into the cavity and reposition around the needle.

公开(公告)号：US20240350739A1

公开(公告)日：2024-10-24

申请号：US18686946

申请日：2021-08-27

申请人： W. L. Gore & Associates, Inc.

发明人： Edward H. Cully ,  Edward C. Gunzel ,  William G. Hardie

IPC分类号： A61M5/315 ,  A61M5/31 ,  B32B1/00 ,  B32B3/10 ,  B32B3/30 ,  B32B27/08 ,  B32B27/32

CPC分类号： A61M5/31505 ,  B32B1/00 ,  B32B3/10 ,  B32B3/30 ,  B32B27/08 ,  B32B27/322 ,  A61M2005/3143 ,  A61M2205/0216 ,  A61M2207/00 ,  B32B2250/24 ,  B32B2274/00 ,  B32B2307/5825 ,  B32B2535/00

摘要： A stopper for use in injector devices, where the stopper having an outer side configured for engagement with an interior bore of a barrel of the injector device. The stoppers may include an elastomer body, a multi-layer barrier coupled to the elastomer body, the multi-layer barrier having an inner surface oriented toward the elastomer body and an outer surface oriented away from the elastomer body, the multi-layer barrier including a first layer and a second layer, the first layer defining the inner surface and the second layer defining the outer surface, and the multi-layer barrier having at least one micro feature formed by the first layer, the at least one micro feature including one or both of a micro groove and/or a micro rib.

公开(公告)号：US20240325667A1

公开(公告)日：2024-10-03

申请号：US18579199

申请日：2022-07-14

申请人： University of Pittsburgh - Of the Commonwealth System of Higher Education ,  UPMC

发明人： Carl H. Snyderman ,  Garrett N. Coyan

IPC分类号： A61M16/04 ,  A61M16/00

CPC分类号： A61M16/0431 ,  A61M16/0003 ,  A61M16/0465 ,  A61M2016/0027 ,  A61M2205/0216 ,  A61M2205/3327 ,  A61M2205/3331 ,  A61M2210/1032

摘要： Disclosed herein are endotracheal tubes that have external baffles near the distal end of the tube to reduce unwanted migration of the tube relative to the trachea and to help prevent materials from passing between the outside of the tube and the tracheal walls. The baffles can be made of soft flexible material that conforms to and seals against the trachea. The baffles can be angled proximally or distally, or both. The baffles can be tapered in thickness and can vary in radial length. Some embodiments can include a supraglottic umbrella. Some embodiments can include an axially expandable portion along the tube. Some embodiments can include a loading tube that helps set the deflection orientation of the baffles within the trachea.

公开(公告)号：US20240325661A1

公开(公告)日：2024-10-03

申请号：US18738084

申请日：2024-06-10

申请人： Syqe Medical Ltd.

发明人： Perry DAVIDSON ,  Aaron SCHORR ,  Binyamin SCHWARTZ ,  Roee LIFSHITZ

IPC分类号： A61M15/00 ,  A61K9/00 ,  A61K31/05 ,  A61K31/352 ,  A61K31/465 ,  A61K36/185 ,  A61K36/81 ,  A61M11/02 ,  A61M11/04 ,  A61M15/06 ,  A61M16/14 ,  A61M16/20 ,  H05B1/02

CPC分类号： A61M15/0028 ,  A61K9/007 ,  A61K9/0073 ,  A61K31/05 ,  A61K31/352 ,  A61K31/465 ,  A61K36/185 ,  A61K36/81 ,  A61M11/041 ,  A61M11/042 ,  A61M15/0001 ,  A61M15/0003 ,  A61M15/0013 ,  A61M15/0015 ,  A61M15/002 ,  A61M15/0045 ,  A61M15/005 ,  A61M15/0051 ,  A61M15/0065 ,  A61M15/0066 ,  A61M15/06 ,  A61M16/14 ,  A61M16/20 ,  H05B1/025 ,  A61M11/02 ,  A61M15/0021 ,  A61M15/0091 ,  A61M2205/0216 ,  A61M2205/3303 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/3368 ,  A61M2205/3569 ,  A61M2205/3592 ,  A61M2205/36 ,  A61M2205/502 ,  A61M2205/52

摘要： An inhaler device for pulmonary delivery of at least one substance from a drug dose cartridge to an inhaling user, including: a first conduit for conducting a carrier airflow to a proximal opening of a mouthpiece for use by the user, a holder configured to position the dose cartridge within the carrier airflow; and a second conduit for conducting a shunting airflow to the mouthpiece without passing through the dose cartridge position. In some embodiments, a controller connected to a valve controls a rate of carrier airflow, for example by controlling the shunting airflow, based on a sensor indication of airflow rate and a target airflow profile.

公开(公告)号：US12102765B2

公开(公告)日：2024-10-01

申请号：US17061544

申请日：2020-10-01

申请人： Fisher & Paykel Healthcare Limited

发明人： Brett John Huddart ,  Jeroen Hammer ,  Matthew Robert Geoff Slight ,  Vitaly Kapelevich ,  David Monroy Felix ,  Callum Ross Gordon ,  Bruce Michael Walls ,  Melissa Catherine Bornholdt ,  Matthew Roger Stephenson ,  Paul Mathew Freestone ,  Ryan Anthony Graham ,  Mark Arvind McLaren

IPC分类号： A61M16/00 ,  A61M16/06 ,  A61M16/08 ,  A61M16/20

CPC分类号： A61M16/0683 ,  A61M16/0666 ,  A61M16/0825 ,  A61M16/0866 ,  A61M16/0875 ,  A61M16/208 ,  A61M16/06 ,  A61M2205/0216 ,  A61M2210/0618

摘要： A headgear system and/or an interface assembly incorporating a headgear system that, in some configurations, is configured to transform from elasticated or “stretchy” behavior to “inelastic” behavior at least in response to normal or expected forces encountered during the intended therapy. In some configurations, upon fitment to the head of a user, the system automatically adjusts toward or to an appropriate size. A headgear portion or assembly for use in combination with a breathing apparatus in some configurations is at least substantially inelastic and is three dimensional in shape. The headgear portion or assembly can comprise a plastic core and a textile casing. The headgear, or part thereof, may also have integrally moulded labels, connectors, adjustment mechanisms and/or grips.

公开(公告)号：US12102764B2

公开(公告)日：2024-10-01

申请号：US16625177

申请日：2018-06-26

申请人： Fisher & Paykel Healthcare Limited

发明人： Christopher Gareth Sims ,  Fadi Karim Moh'd Mashal ,  Vitaly Kapelevich ,  Mark Arvind McLaren ,  Silas Sao Jin Siew ,  Jonathan Mark Downey ,  Christopher Michael Wong ,  Matthew Aaron Bradley ,  Janine Elizabeth Collins ,  Dillan Patel ,  Steve Thomas ,  Chris Onin Limpin Hipolito ,  Priyanka Ferdinand Pereira ,  Matthew Robert Geoff Slight ,  David Monroy Felix ,  Xin Yue Zhu ,  Jonathan Tong Lok Sng ,  Arvin San Jose Gardiola ,  Stephen Francis Heffernan ,  Christine Marie Lynch ,  Wen Dong Huang ,  Bruce Michael Walls ,  Jeremy Owen Young ,  Tony William Spear ,  Jake Baker Hocking ,  Melissa Catherine Bornholdt

IPC分类号： A61M16/06

CPC分类号： A61M16/0683 ,  A61M16/0622 ,  A61M2205/0216 ,  A61M2210/0618 ,  A61M2210/0625

摘要： A respiratory mask system includes a mask interface and a headgear assembly. The headgear assembly is adjustable and comprised of an elastic portion, a non-elastic portion and a restriction mechanism configured to provide a force resisting movement of the non-elastic portion when the elastic portion is extended. There is a support beam coupled to the non-elastic portion and extending along a portion of the headgear that is curved along its longitudinal extent. In this way particular seal modules can be comfortably fitted to a user and any blow off force is mitigated. A particular example of the respiratory mask system includes provision for removable attachment between the seal and a mask frame, the mask frame and a yoke of the headgear; and between a conduit and the mask frame.

公开(公告)号：US12090305B2

公开(公告)日：2024-09-17

申请号：US17661907

申请日：2022-05-03

申请人： W. L. Gore & Associates, Inc.

发明人： Greg Rusch ,  Robert C. Basham

IPC分类号： A61M5/315 ,  A61L31/04 ,  A61M5/31

CPC分类号： A61M5/31505 ,  A61L31/048 ,  A61M5/31513 ,  A61M2005/3101 ,  A61M2005/31506 ,  A61M2205/0216 ,  A61M2205/0222 ,  A61M2205/0238

摘要： The present disclosure relates to a medical delivery device that includes a barrel having an inner surface, a plunger rod having a distal end inserted within the barrel, and a stopper attached to the distal end of the plunger rod and contacting at least a portion of the inner surface of the barrel. In at least one embodiment, the inner surface is hydrophilic. The stopper may include an elastomeric body, one or more fluoropolymer layers, and two or more ribs laminated with the one or more fluoropolymer layers. In some embodiments, the contact width between at least one rib having a sealing surface and the portion of the inner surface of the barrel measured at a compressibility of greater than about 7.9% of the stopper is less than about 1.0 mm.

公开(公告)号：US20240299665A1

公开(公告)日：2024-09-12

申请号：US18668491

申请日：2024-05-20

申请人： kaleo, Inc.

发明人： Paul F. MEYERS ,  Michael J. ROE

IPC分类号： A61M5/20

CPC分类号： A61M5/2053 ,  A61M5/2046 ,  A61M2205/0216 ,  A61M2205/3334

摘要： An apparatus includes a housing, an energy storage member, a carrier, a medicament container, and a delivery control mechanism. The housing defines a gas chamber configured to receive pressurized gas from the energy storage member to pressurize the gas chamber. The carrier has a proximal surface that defines a portion of the gas chamber. The medicament container is coupled to the carrier and has a distal end portion coupled to a delivery member. The medicament container contains a medicament and includes an elastomeric member that seals the medicament within the medicament container. The delivery control mechanism is coupled to a proximal end portion of the medicament container and includes a flow restriction member for regulating a pressure supplied by the gas chamber and entering into the medicament container that acts on the elastomeric member.

公开(公告)号：US20240269443A1

公开(公告)日：2024-08-15

申请号：US18419536

申请日：2024-01-22

申请人： SHANGHAI WD PHARMACEUTICAL CO., LTD

发明人： Liang Chang DONG ,  Ming FAN ,  Wenbo MA ,  Jingmin SHI ,  Danyong ZHANG ,  Gang WU

IPC分类号： A61M31/00

CPC分类号： A61M31/002 ,  A61M2205/0216 ,  A61M2205/0233 ,  A61M2205/025 ,  A61M2207/10 ,  A61M2210/0637

摘要： The present disclosure relates to an oral retention device and an osmotic pump tablet, preparation method therefor and application thereof. The medicinal tablet is inserted into the oral retention device to form a pharmaceutical device composition. The pharmaceutical device composition is fixed on the matching teeth in the oral cavity to achieve sustained release of the drug within a certain period of time. A high-dose osmotic pump tablet of the present disclosure with the absorption window of active pharmaceutical ingredients limited to the upper gastrointestinal tract has a high drug loading capacity and can achieve a good therapeutic effect.

公开(公告)号：US20240269413A1

公开(公告)日：2024-08-15

申请号：US18441128

申请日：2024-02-14

申请人： BRANDON SCOTT MCDONALD

发明人： BRANDON SCOTT MCDONALD

IPC分类号： A61M16/06

CPC分类号： A61M16/0616 ,  A61M2205/0216 ,  A61M2205/3331 ,  A61M2210/0625

摘要： A mask assembly is provided with a substrate sized to cover a mouth of a user. A plurality of ports is formed through the substrate. A valve seal is mounted to the substrate. The valve seal has a plurality of valves formed through the valve seal. A peripheral seal is mounted to the substrate to seal around the valve to seal the substrate and the valve seal to a face of the user around the mouth of the user.