公开(公告)号：US6156882A

公开(公告)日：2000-12-05

申请号：US105596

申请日：1998-06-26

申请人： Hans-Jorg Buhring ,  Irene Rappold

发明人： Hans-Jorg Buhring ,  Irene Rappold

IPC分类号： A61K38/00 ,  C07K14/705 ,  C07K16/28 ,  C12N15/06 ,  C12P21/08 ,  G01N33/569 ,  C12N9/64 ,  C07K16/00

CPC分类号： G01N33/56972 ,  C07K14/70596 ,  C07K16/2896 ,  A61K38/00 ,  G01N2333/70582 ,  G01N2333/71

摘要： The invention relates to a monoclonal antibody specifically binding to the human FLT3/FLK2 receptor protein. The invention further relates to hybridoma cells producing such an antibody, as well as to a method for generation of such hybridoma cells. The monoclonal antibody is the antibody produced and released by hybridoma cells deposited under No. DSM 2249 at the German Collection of Microorganisms and Cell Cultures (DSMZ) and designated as 4G8B4B12.

摘要翻译： 本发明涉及与人FLT3 / FLK2受体蛋白特异性结合的单克隆抗体。 本发明还涉及产生这种抗体的杂交瘤细胞，以及用于产生这种杂交瘤细胞的方法。 单克隆抗体是由DSM 2249在德国微生物和细胞培养物收集库（DSMZ）上保藏并被指定为4G8B4B12的杂交瘤细胞产生和释放的抗体。