GLP-1 RECEPTOR AGONISTS FOR ISLET CELL TRANSPLANTATION
    1.
    发明申请
    GLP-1 RECEPTOR AGONISTS FOR ISLET CELL TRANSPLANTATION 有权
    GLP-1受体激动剂用于细胞移植

    公开(公告)号:US20140017208A1

    公开(公告)日:2014-01-16

    申请号:US13996093

    申请日:2011-12-20

    申请人: Kwame Osei

    发明人: Kwame Osei

    IPC分类号: A61K35/39 A61K38/16 A61K38/26

    CPC分类号: A61K35/39 A61K38/16 A61K38/26

    摘要: The disclosure provides methods for treating diabetes by promoting graft survival and improved graft function in a patient receiving an islet transplant by treating the patient with a GLP-1 receptor agonist compound prior to the islet transplant. The methods may also comprise treating the islets with a GLP-1 receptor agonist compound prior to transplanting them in a patient. The methods may eliminate the need for immunosuppressive therapy in islet transplants. Any GLP-1 receptor agonist compound know in the art can be used in the methods described herein.

    摘要翻译: 本公开提供了通过在胰岛移植之前通过用GLP-1受体激动剂化合物治疗患者来促进接受胰岛移植的患者中的移植物存活和改善移植物功能来治疗糖尿病的方法。 所述方法还可以包括在将它们移植到患者体内之前用GLP-1受体激动剂化合物处理胰岛。 该方法可以消除胰岛移植中免疫抑制治疗的需要。 本领域已知的任何GLP-1受体激动剂化合物可用于本文所述的方法。

    GLP-1 receptor agonists for islet cell transplantation
    2.
    发明授权
    GLP-1 receptor agonists for islet cell transplantation 有权
    GLP-1受体激动剂用于胰岛细胞移植

    公开(公告)号:US09161953B2

    公开(公告)日:2015-10-20

    申请号:US13996093

    申请日:2011-12-20

    申请人: Kwame Osei

    发明人: Kwame Osei

    CPC分类号: A61K35/39 A61K38/16 A61K38/26

    摘要: The disclosure provides methods for treating diabetes by promoting graft survival and improved graft function in a patient receiving an islet transplant by treating the patient with a GLP-1 receptor agonist compound prior to the islet transplant. The methods may also comprise treating the islets with a GLP-1 receptor agonist compound prior to transplanting them in a patient. The methods may eliminate the need for immunosuppressive therapy in islet transplants. Any GLP-1 receptor agonist compound know in the art can be used in the methods described herein.

    摘要翻译: 本公开提供了通过在胰岛移植之前通过用GLP-1受体激动剂化合物治疗患者来促进接受胰岛移植的患者中的移植物存活和改善移植物功能来治疗糖尿病的方法。 所述方法还可以包括在将它们移植到患者体内之前用GLP-1受体激动剂化合物处理胰岛。 该方法可以消除胰岛移植中免疫抑制治疗的需要。 本领域已知的任何GLP-1受体激动剂化合物可用于本文所述的方法。

    System and Method for Atmospheric Correction of Information
    3.
    发明申请
    System and Method for Atmospheric Correction of Information 有权
    信息大气校正系统与方法

    公开(公告)号:US20130006534A1

    公开(公告)日:2013-01-03

    申请号:US13174864

    申请日:2011-07-01

    IPC分类号: G06F19/00 G06F15/00

    CPC分类号: G01S3/7803 G01W1/00

    摘要: An atmospheric correction system (ACS) is proposed, which accounts for the errors resulting from the in-homogeneities in the operational atmosphere along the slant path by constructing atmospheric profiles from the data along the actual target to sensor slant-range path. The ACS generates a slant-range path based on the arbitrary geometry that models the sensor to target relationship. This path takes the atmosphere and obstructions between the two endpoints into account when determining the atmospheric profile. The ACS uses assimilation to incorporate weather data from multiple sources and constructs an atmospheric profile from the best available data. The ACS allows the user to take advantage of variable weather and information along the path that can lead to increased accuracy in the derived atmospheric compensation value.

    摘要翻译: 提出了大气校正系统(ACS),其通过从沿着实际目标的数据到传感器倾斜路径构造大气剖面来解释沿着斜道的操作气氛中的均匀性所导致的误差。 ACS根据将传感器建模为目标关系的任意几何生成一个倾斜范围路径。 当确定大气剖面时,这条路径会考虑两个端点之间的气氛和障碍物。 ACS使用同化来整合来自多个源的天气数据,并从最佳可用数据构建大气剖面。 ACS允许用户利用沿着路径的可变天气和信息,这可以导致导出的大气补偿值的精度提高。

    Apparatus and method for test-stimuli compaction
    4.
    发明授权
    Apparatus and method for test-stimuli compaction 失效
    用于测试刺激压实的装置和方法

    公开(公告)号:US07260793B2

    公开(公告)日:2007-08-21

    申请号:US09985768

    申请日:2001-11-06

    IPC分类号: G06F15/70

    摘要: Based on the concept of minimization, a method of static compaction has been developed for a digital circuit. The compaction method is a combination of two main procedures: one for the selection of essential test stimuli and the other for the elimination of redundant test stimuli, and effective in minimizing any set of test stimuli without modifying any of the test stimuli.

    摘要翻译: 基于最小化的概念,已经开发了一种用于数字电路的静态压实方法。 压实方法是两个主要步骤的组合:一个用于选择基本测试刺激,另一个用于消除冗余测试刺激,并且有效地使任何一组测试刺激最小化,而不修改任何测试刺激。

    Device and method for testing phase-locked loops
    5.
    发明授权
    Device and method for testing phase-locked loops 失效
    用于测试锁相环的装置和方法

    公开(公告)号:US06642701B2

    公开(公告)日:2003-11-04

    申请号:US10050863

    申请日:2002-01-18

    IPC分类号: G01R2312

    摘要: A phase-locked loop (PLL) is tested based on a divide-and-conquer strategy. First, digital components in the PLL are isolated from analog components and tested. Next, the digital components are connected to the analog components and the PLL is exercised by causing it to undergo a series of frequency transitions.

    摘要翻译: 锁相环(PLL)是基于分治策略进行测试的。 首先,PLL中的数字组件与模拟组件隔离并进行测试。 接下来,数字组件连接到模拟组件,并且通过使PLL经历一系列频率转换来执行PLL。

    System and method for atmospheric correction of information
    6.
    发明授权
    System and method for atmospheric correction of information 有权
    信息大气校正的系统和方法

    公开(公告)号:US09097792B2

    公开(公告)日:2015-08-04

    申请号:US13174864

    申请日:2011-07-01

    IPC分类号: G01W1/00 G01S3/78

    CPC分类号: G01S3/7803 G01W1/00

    摘要: An atmospheric correction system (ACS) is proposed, which accounts for the errors resulting from the in-homogeneities in the operational atmosphere along the slant path by constructing atmospheric profiles from the data along the actual target to sensor slant-range path. The ACS generates a slant-range path based on the arbitrary geometry that models the sensor to target relationship. This path takes the atmosphere and obstructions between the two endpoints into account when determining the atmospheric profile. The ACS uses assimilation to incorporate weather data from multiple sources and constructs an atmospheric profile from the best available data. The ACS allows the user to take advantage of variable weather and information along the path that can lead to increased accuracy in the derived atmospheric compensation value.

    摘要翻译: 提出了大气校正系统(ACS),其通过从沿着实际目标的数据到传感器倾斜路径构造大气剖面来解释沿着斜道的操作气氛中的均匀性所导致的误差。 ACS根据将传感器建模为目标关系的任意几何生成一个倾斜范围路径。 当确定大气剖面时,这条路径会考虑两个端点之间的气氛和障碍物。 ACS使用同化来整合来自多个源的天气数据,并从最佳可用数据构建大气剖面。 ACS允许用户利用沿着路径的可变天气和信息,这可以导致导出的大气补偿值的精度提高。