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公开(公告)号:US20110152346A1
公开(公告)日:2011-06-23
申请号:US12741527
申请日:2008-11-05
申请人: Mati Karleson , Erkki Truve , Allan Olspert , Cecilia Sarmiento , Mart Saarma
发明人: Mati Karleson , Erkki Truve , Allan Olspert , Cecilia Sarmiento , Mart Saarma
IPC分类号: A61K31/7088 , C12N5/07 , C12P19/34 , C07H21/00 , C12Q1/68 , G01N33/53 , A61P37/02 , A61P31/12 , A61P35/00
CPC分类号: C12N15/111 , C12N15/113 , C12N2310/33 , C12N2310/352 , C12N2320/51 , Y10T436/143333
摘要: The invention is concerned with the use of oligonucleotide analogs that contain specifically modified DNA bases to be used in hybridization of nucleic acids, polymerase chain reaction (PCR) and siRNA-mediated gene silencing (RNAi).
摘要翻译: 本发明涉及使用含有特异性修饰的DNA碱基用于核酸杂交,聚合酶链反应(PCR)和siRNA介导的基因沉默(RNAi)的寡核苷酸类似物。