-
公开(公告)号:US07067639B2
公开(公告)日:2006-06-27
申请号:US10321857
申请日:2002-12-16
申请人: Cornelis J. Leenhouts , Ranjan Ramasamy , Anton Steen , Jan Kok , Girbe Buist , Oscar P. Kuipers
发明人: Cornelis J. Leenhouts , Ranjan Ramasamy , Anton Steen , Jan Kok , Girbe Buist , Oscar P. Kuipers
IPC分类号: A61K39/00 , A61K39/38 , A61K39/02 , A61K45/00 , A61K47/00 , C12N1/00 , C07K1/00 , C07K14/00 , C07K16/00 , C07K17/00
CPC分类号: C07K14/335 , A61K38/00 , C07K2319/00 , Y02A50/411 , Y10S530/81
摘要: Methods for improving binding of a proteinaceous substance to cell-wall material of a Gram-positive bacterium are disclosed. The proteinaceous substance includes an AcmA cell-wall binding domain, homolog or functional derivative thereof. The method includes treating the cell-wall material with a solution capable of removing a cell-wall component such as a protein, lipoteichoic acid or carbohydrate from the cell-wall material and contacting the proteinaceous substance with the cell-wall material.
-
公开(公告)号:US5594103A
公开(公告)日:1997-01-14
申请号:US129151
申请日:1993-10-07
IPC分类号: A23C19/11 , C07K14/315 , C12N1/21 , C12N15/74
CPC分类号: C12N15/746 , A23C19/11 , C07K14/315
摘要: The invention relates primarily to a number of lantibiotics similar to nisin A, which differ from nisin A by substitution, deletion or insertion of one or more amino acids, such as the naturally occurring analog of nisin A, termed nisin Z. Lantibiotics of this type are particularly suitable for preserving foodstuffs for humans and animals. This preservation takes place by the use of these lantibiotics themselves or of microorganisms producing these lantibiotics, in particular lactic acid bacteria, in the preparation or storage of foodstuffs.
摘要翻译: PCT No.PCT / NL92 / 00068 Sec。 371日期:1993年10月7日 102(e)日期1993年10月7日PCT提交1992年4月9日PCT公布。 公开号WO92 / 18633 日期1992年10月29日本发明主要涉及与乳链菌肽A相似的许多类似于乳链菌肽A的羊毛硫抗生素,其不同于乳链菌肽A,通过取代,缺失或插入一个或多个氨基酸,例如天然存在的乳链菌肽A类似物,称为乳链菌肽Z 这种类型的抗生素特别适用于保存人类和动物的食物。 这种保存是通过使用这些兰生抗生素本身或生产这些羊毛硫抗生素的微生物,特别是乳酸菌在食品的制备或储存中进行的。
-