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    GENETIC POLYMORPHISMS ASSOCIATED WITH AUTOINFLAMMATORY DISEASES, METHODS OF DETECTION AND USES THEREOF
    1.
    发明申请
    GENETIC POLYMORPHISMS ASSOCIATED WITH AUTOINFLAMMATORY DISEASES, METHODS OF DETECTION AND USES THEREOF 审中-公开
    与自身免疫性疾病相关的遗传多态性，检测方法及其用途

    公开(公告)号：US20100008934A1

    公开(公告)日：2010-01-14

    申请号：US12494800

    申请日：2009-06-30

    申请人： Steven J. SCHRODI ,  Yonghong LI

    发明人： Steven J. SCHRODI ,  Yonghong LI

    IPC分类号： A61K39/395 ,  C12Q1/68 ,  A61P37/06

    CPC分类号： C12Q1/6883 ,  C07K16/244 ,  C12Q2600/106 ,  C12Q2600/136 ,  C12Q2600/156 ,  C12Q2600/158 ,  C12Q2600/172

    摘要： The present invention provides compositions and methods based on genetic polymorphisms that are associated with autoinflammatory diseases such as psoriasis. For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and variant proteins, and methods of using the nucleic acid molecules and proteins as well as methods of using reagents for their detection.

    摘要翻译： 本发明提供了与自身炎症性疾病如牛皮癣相关的遗传多态性的组合物和方法。 例如，本发明涉及含有多态性的核酸分子，由这些核酸分子编码的变体蛋白，用于检测多态型核酸分子和变体蛋白的试剂，以及使用核酸分子和蛋白质的方法以及方法 使用试剂进行检测。

    Genetic polymorphisms associated with rheumatoid arthritis, methods of detection and uses thereof
    2.
    发明申请
    Genetic polymorphisms associated with rheumatoid arthritis, methods of detection and uses thereof 有权
    与类风湿关节炎相关的遗传多态性，检测方法及其应用

    公开(公告)号：US20090162346A1

    公开(公告)日：2009-06-25

    申请号：US12231877

    申请日：2008-09-04

    申请人： Steven J. Schrodi ,  Ann B. Begovich

    发明人： Steven J. Schrodi ,  Ann B. Begovich

    IPC分类号： A61K39/395 ,  C12Q1/68 ,  A61P19/02

    CPC分类号： C12Q1/6883 ,  C12Q2600/106 ,  C12Q2600/118 ,  C12Q2600/136 ,  C12Q2600/156 ,  C12Q2600/158 ,  C12Q2600/172

    摘要： The present invention provides compositions and methods based on genetic polymorphisms that are associated with autoimmune disease, particularly rheumatoid arthritis. For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and variant proteins, and methods of using the nucleic acid molecules and proteins as well as methods of using reagents for their detection.

    摘要翻译： 本发明提供了基于与自身免疫疾病特别是类风湿性关节炎有关的遗传多态性的组合物和方法。 例如，本发明涉及含有多态性的核酸分子，由这些核酸分子编码的变体蛋白，用于检测多态型核酸分子和变体蛋白的试剂，以及使用核酸分子和蛋白质的方法以及方法 使用试剂进行检测。

    GENETIC POLYMORPHISMS ASSOCIATED WITH RHEUMATOID ARTHRITIS, METHODS OF DETECTION AND USES THEREOF
    3.
    发明申请
    GENETIC POLYMORPHISMS ASSOCIATED WITH RHEUMATOID ARTHRITIS, METHODS OF DETECTION AND USES THEREOF 审中-公开
    与流感嗜血杆菌相关的遗传多态性，检测方法及其用途

    公开(公告)号：US20110293626A1

    公开(公告)日：2011-12-01

    申请号：US12953833

    申请日：2010-11-24

    申请人： Steven J. SCHRODI ,  Ann B. BEGOVICH

    发明人： Steven J. SCHRODI ,  Ann B. BEGOVICH

    IPC分类号： A61K39/395 ,  C40B30/04 ,  A61P19/02 ,  C12Q1/68

    CPC分类号： C12Q1/6883 ,  C12Q2600/106 ,  C12Q2600/118 ,  C12Q2600/136 ,  C12Q2600/156 ,  C12Q2600/158 ,  C12Q2600/172

    摘要： The present invention provides compositions and methods based on genetic polymorphisms that are associated with autoimmune disease, particularly rheumatoid arthritis. For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and variant proteins, and methods of using the nucleic acid molecules and proteins as well as methods of using reagents for their detection.

    摘要翻译： 本发明提供了基于与自身免疫疾病特别是类风湿性关节炎有关的遗传多态性的组合物和方法。 例如，本发明涉及含有多态性的核酸分子，由这些核酸分子编码的变体蛋白，用于检测多态型核酸分子和变体蛋白的试剂，以及使用核酸分子和蛋白质的方法以及方法 使用试剂进行检测。