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1.发明申请公开(公告)号：US20110224217A1
公开(公告)日：2011-09-15
申请号：US13113135
申请日：2011-05-23
申请人： Deborah Sue Mortensen , Maria Mercedes Delgado Mederos , John Joseph Sapienza , Ronald J. Albers , Steven Spencer Clareen , Kimberly Lyn Schwarz , Jason Simon Parnes , Jennifer R. Riggs , Patrick William Papa , Sayee Gajanan Hegde , Jeffrey Mark McKenna
发明人： Deborah Sue Mortensen , Maria Mercedes Delgado Mederos , John Joseph Sapienza , Ronald J. Albers , Steven Spencer Clareen , Kimberly Lyn Schwarz , Jason Simon Parnes , Jennifer R. Riggs , Patrick William Papa , Sayee Gajanan Hegde , Jeffrey Mark McKenna
IPC分类号： A61K31/519 , C12N9/99 , A61K31/522 , A61P35/00 , A61P29/00 , A61P37/02 , A61P3/00 , A61P17/06 , A61P11/06 , A61P11/02 , A61P11/08 , A61P11/00 , A61P3/04 , A61P3/10 , A61P1/00 , A61P25/28 , A61P19/02
CPC分类号： C07D473/00 , C07D473/28 , C07D473/32 , C07D475/00
摘要： Provided herein are Heteroaryl Compounds having the following structure: wherein R1, R3, R4, L, X, Y, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.
摘要翻译： 本文提供了具有以下结构的杂芳基化合物：其中R 1，R 3，R 4，L，X，Y，A和B如本文所定义，包含有效量的杂芳基化合物的组合物和治疗或预防癌症， ，免疫条件，代谢条件和通过抑制激酶途径可治疗或可预防的病症，包括向有需要的患者施用有效量的杂芳基化合物。
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2.发明授权公开(公告)号：US08383634B2
公开(公告)日：2013-02-26
申请号：US13113135
申请日：2011-05-23
申请人： Deborah Sue Mortensen , Maria Mercedes Delgado Mederos , John Joseph Sapienza , Ronald J. Albers , Steven Spencer Clareen , Kimberly Lyn Schwarz , Jason Simon Parnes , Jennifer R. Riggs , Patrick William Papa , Sayee Gajanan Hegde , Jeffrey Mark McKenna
发明人： Deborah Sue Mortensen , Maria Mercedes Delgado Mederos , John Joseph Sapienza , Ronald J. Albers , Steven Spencer Clareen , Kimberly Lyn Schwarz , Jason Simon Parnes , Jennifer R. Riggs , Patrick William Papa , Sayee Gajanan Hegde , Jeffrey Mark McKenna
IPC分类号： A61P11/06 , A61P3/10 , A61P31/04 , C07D473/28 , C07D473/18 , C07D519/00 , C07D487/04 , A61K31/522
CPC分类号： C07D473/00 , C07D473/28 , C07D473/32 , C07D475/00
摘要： Provided herein are Heteroaryl Compounds having the following structure: wherein R1, R3, R4, L, X, Y, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.
摘要翻译： 本文提供了具有以下结构的杂芳基化合物：其中R 1，R 3，R 4，L，X，Y，A和B如本文所定义，包含有效量的杂芳基化合物的组合物和治疗或预防癌症， ，免疫条件，代谢条件和通过抑制激酶途径可治疗或可预防的病症，包括向有需要的患者施用有效量的杂芳基化合物。
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3.发明授权公开(公告)号：US07968556B2
公开(公告)日：2011-06-28
申请号：US11975657
申请日：2007-10-18
申请人： Deborah Sue Mortensen , Maria Mercedes Delgado Mederos , John Joseph Sapienza , Ronald J. Albers , Steven Spencer Clareen , Kimberly Lyn Schwarz , Jason Simon Parnes , Jennifer R. Riggs , Patrick William Papa , Sayee Gajanan Hegde , Jeffrey Mark McKenna
发明人： Deborah Sue Mortensen , Maria Mercedes Delgado Mederos , John Joseph Sapienza , Ronald J. Albers , Steven Spencer Clareen , Kimberly Lyn Schwarz , Jason Simon Parnes , Jennifer R. Riggs , Patrick William Papa , Sayee Gajanan Hegde , Jeffrey Mark McKenna
IPC分类号： C07D473/28 , C07D473/18 , C07D519/00 , A61K31/522 , C07D475/00 , C07D487/04 , A61P3/10 , A61P31/04 , A61P11/06
CPC分类号： C07D473/00 , C07D473/28 , C07D473/32 , C07D475/00
摘要： Provided herein are Heteroaryl Compounds having the following structure: wherein R1, R3, R4, L, X, Y, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.
摘要翻译： 本文提供了具有以下结构的杂芳基化合物：其中R 1，R 3，R 4，L，X，Y，A和B如本文所定义，包含有效量的杂芳基化合物的组合物和治疗或预防癌症， ，免疫条件，代谢条件和通过抑制激酶途径可治疗或可预防的病症，包括向有需要的患者施用有效量的杂芳基化合物。
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4.发明申请公开(公告)号：US20090042890A1
公开(公告)日：2009-02-12
申请号：US11975657
申请日：2007-10-18
申请人： Deborah Sue Mortensen , Maria Mercedes Delgado Mederos , John Joseph Sapienza , Ronald J. Albers , Steven Spencer Clareen , Kimberly Lyn Schwarz , Jason Simon Parnes , Jennifer R. Riggs , Patrick William Papa , Sayee Gajanan Hegde , Jeffrey Mark McKenna
发明人： Deborah Sue Mortensen , Maria Mercedes Delgado Mederos , John Joseph Sapienza , Ronald J. Albers , Steven Spencer Clareen , Kimberly Lyn Schwarz , Jason Simon Parnes , Jennifer R. Riggs , Patrick William Papa , Sayee Gajanan Hegde , Jeffrey Mark McKenna
IPC分类号： A61K31/4985 , C07D401/14 , C07D473/00 , A61P35/00 , A61P29/00 , C12N5/00 , A61P37/00 , A61P3/00 , C07D475/00 , A61K31/52
CPC分类号： C07D473/00 , C07D473/28 , C07D473/32 , C07D475/00
摘要： Provided herein are Heteroaryl Compounds having the following structure: wherein R1, R3, R4, L, X, Y, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.
摘要翻译： 本文提供了具有以下结构的杂芳基化合物：其中R 1，R 3，R 4，L，X，Y，A和B如本文所定义，包含有效量的杂芳基化合物的组合物和治疗或预防癌症， ，免疫条件，代谢条件和通过抑制激酶途径可治疗或可预防的病症，包括向有需要的患者施用有效量的杂芳基化合物。
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