公开(公告)号：US20090105814A1

公开(公告)日：2009-04-23

申请号：US12249388

申请日：2008-10-10

Applicant: Adam Groothuis ,  Matthew Krever ,  Timothy Lash ,  Rudolph Cedro ,  Ted Bachman ,  Paul D'Antonio ,  Erin Black ,  Daniel H. Olsen ,  Salvatore G. Caldarise ,  Natalie D. Macon ,  Paritosh Dhawale

Inventor： Adam Groothuis ,  Matthew Krever ,  Timothy Lash ,  Rudolph Cedro ,  Ted Bachman ,  Paul D'Antonio ,  Erin Black ,  Daniel H. Olsen ,  Salvatore G. Caldarise ,  Natalie D. Macon ,  Paritosh Dhawale

IPC: A61F2/24

CPC classification number: A61F2/2466 ,  A61B17/00234 ,  A61B17/29 ,  A61B2017/00243 ,  A61B2017/00292 ,  A61B2017/2905 ,  A61B2017/2923 ,  A61B2017/2925 ,  A61B2017/2927 ,  A61B2017/2939 ,  A61B2017/2946

Abstract: A system and method for the treatment of mitral valve regurgitation by reshaping the mitral valve annulus using one or more plications of annular or adjacent tissue each fixed by a retainer is described. The system includes four devices to achieve such percutaneous direct plication annuloplasty. The first is a crossing catheter having a prolapseable or curved tip. Second, a deflecting guide catheter is used to provide a means for guiding the plication device into proper position at the subvalvular region of the mitral valve annulus. Third, the plication device is then used to make plications in the subvalvular region of the mitral valve annulus. Fourth, a “C” shaped retainer with deformable ends is deployed by the plication device in order to retain the plicated tissue in the plicated form. A transseptal approach may be used to plicate and retain tissue on the atrial side of the mitral valve to achieve a reduction in mitral valve regurgitation.

Abstract translation: 描述了通过使用由保持器固定的环形或相邻组织的一个或多个点进行重新形成二尖瓣环的治疗二尖瓣反流的系统和方法。 该系统包括四个装置来实现这种经皮直接瓣膜瓣成形术。 第一个是具有可脱垂或弯曲的尖端的交叉导管。 第二，偏转引导导管用于提供用于将折叠装置引导到二尖瓣环的下瓣区域的适当位置的装置。 第三，折叠装置然后用于在二尖瓣环的亚瓣膜区域进行。肿。 第四，通过打浆装置展开具有可变形端部的“C”形保持器，以便将复制的组织保持在复制形式中。 经口途径可用于将二尖瓣心房侧的组织挽留并保留，以减少二尖瓣反流。

公开(公告)号：US08226709B2

公开(公告)日：2012-07-24

申请号：US12249388

申请日：2008-10-10

Applicant: Adam Groothuis ,  Matthew Krever ,  Timothy Lash ,  Rudolph Cedro ,  Ted Bachman ,  Paul D'Antonio ,  Erin Black ,  Daniel H. Olsen ,  Salvatore G. Caldarise ,  Natalie D. Macon ,  Paritosh Dhawale

Inventor： Adam Groothuis ,  Matthew Krever ,  Timothy Lash ,  Rudolph Cedro ,  Ted Bachman ,  Paul D'Antonio ,  Erin Black ,  Daniel H. Olsen ,  Salvatore G. Caldarise ,  Natalie D. Macon ,  Paritosh Dhawale

IPC: A61F2/24 ,  A61B17/10

CPC classification number: A61F2/2466 ,  A61B17/00234 ,  A61B17/29 ,  A61B2017/00243 ,  A61B2017/00292 ,  A61B2017/2905 ,  A61B2017/2923 ,  A61B2017/2925 ,  A61B2017/2927 ,  A61B2017/2939 ,  A61B2017/2946

Abstract: A system and method for the treatment of mitral valve regurgitation by reshaping the mitral valve annulus using one or more plications of annular or adjacent tissue each fixed by a retainer is described. The system includes four devices to achieve such percutaneous direct plication annuloplasty. The first is a crossing catheter having a prolapseable or curved tip. Second, a deflecting guide catheter is used to provide a means for guiding the plication device into proper position at the subvalvular region of the mitral valve annulus. Third, the plication device is then used to make plications in the subvalvular region of the mitral valve annulus. Fourth, a “C” shaped retainer with deformable ends is deployed by the plication device in order to retain the plicated tissue in the plicated form. A transseptal approach may be used to plicate and retain tissue on the atrial side of the mitral valve to achieve a reduction in mitral valve regurgitation.

Abstract translation: 描述了通过使用由保持器固定的环形或相邻组织的一个或多个点进行重新形成二尖瓣环的治疗二尖瓣反流的系统和方法。 该系统包括四个装置来实现这种经皮直接瓣膜瓣成形术。 第一个是具有可脱垂或弯曲的尖端的交叉导管。 第二，偏转引导导管用于提供用于将折叠装置引导到二尖瓣环的下瓣区域的适当位置的装置。 第三，折叠装置然后用于在二尖瓣环的亚瓣膜区域进行。肿。 第四，通过打浆装置展开具有可变形端部的“C”形保持器，以便将复制的组织保持在复制形式中。 经口途径可用于将二尖瓣心房侧的组织挽留并保留，以减少二尖瓣反流。

公开(公告)号：US20130172990A1

公开(公告)日：2013-07-04

申请号：US13534158

申请日：2012-06-27

Applicant: ADAM GROOTHUIS ,  Matthew Krever ,  Timothy Lash ,  Rudolph Cedro ,  Ted Bachman ,  Paul D'Antonio ,  Erin Black ,  Daniel H. Olsen ,  Salvatore G. Caldarise ,  Natalie D. Macon ,  Paritosh Dhawale

Inventor： ADAM GROOTHUIS ,  Matthew Krever ,  Timothy Lash ,  Rudolph Cedro ,  Ted Bachman ,  Paul D'Antonio ,  Erin Black ,  Daniel H. Olsen ,  Salvatore G. Caldarise ,  Natalie D. Macon ,  Paritosh Dhawale

IPC: A61F2/24

CPC classification number: A61F2/2466 ,  A61B17/00234 ,  A61B17/29 ,  A61B2017/00243 ,  A61B2017/00292 ,  A61B2017/2905 ,  A61B2017/2923 ,  A61B2017/2925 ,  A61B2017/2927 ,  A61B2017/2939 ,  A61B2017/2946

Abstract: A system and method for the treatment of mitral valve regurgitation by reshaping the mitral valve annulus using one or more plications of annular or adjacent tissue each fixed by a retainer is described. The system includes four devices to achieve such percutaneous direct plication annuloplasty. The first is a crossing catheter having a prolapseable or curved tip. Second, a deflecting guide catheter is used to provide a means for guiding the plication device into proper position at the subvalvular region of the mitral valve annulus. Third, the plication device is then used to make plications in the subvalvular region of the mitral valve annulus. Fourth, a “C” shaped retainer with deformable ends is deployed by the plication device in order to retain the plicated tissue in the plicated form.

Abstract translation: 描述了通过使用由保持器固定的环形或相邻组织的一个或多个点进行重新形成二尖瓣环的治疗二尖瓣反流的系统和方法。 该系统包括四个装置来实现这种经皮直接瓣膜瓣成形术。 第一个是具有可脱垂或弯曲的尖端的交叉导管。 第二，偏转引导导管用于提供用于将折叠装置引导到二尖瓣环的下瓣区域的适当位置的装置。 第三，折叠装置然后用于在二尖瓣环的亚瓣膜区域进行。肿。 第四，通过打浆装置展开具有可变形端部的“C”形保持器，以便将复制的组织保持在复制形式中。

公开(公告)号：US20100094334A1

公开(公告)日：2010-04-15

申请号：US12349302

申请日：2009-01-06

Applicant: Matthew Krever ,  Rudolph Cedro, JR. ,  Timothy Lash ,  David Majercak ,  Daniel H. Olsen

Inventor： Matthew Krever ,  Rudolph Cedro, JR. ,  Timothy Lash ,  David Majercak ,  Daniel H. Olsen

IPC: A61B17/00

CPC classification number: A61B17/0644 ,  A61B17/122 ,  A61B17/1285 ,  A61B2017/00243

Abstract: A system for the treatment of mitral valve regurgitation by reshaping the mitral valve annulus using one or more plications of annular tissue each fixed by a retaining clip is described. The system includes four devices to achieve such percutaneous direct plication annuloplasty. The first is a prolapsable crossing catheter. Second, a deflecting guide catheter is used to provide a means for guiding the plication device into proper position at the subvalvular region of the mitral valve annulus. The plication device is then used to make plications in the subvalvular region of the mitral valve annulus. Fourth, a formable linear retainer clip is deployed by the plication device in order to retain the plicated tissue in the plicated form. The formable linear retainer is formed into a reverse “C” clip by the jaws of the plication device acting in conjunction with a retainer pusher.

Abstract translation: 描述了一种通过使用由固定夹固定的环形组织的一个或多个引导来重塑二尖瓣环的治疗二尖瓣反流的系统。 该系统包括四个装置来实现这种经皮直接瓣膜瓣成形术。 第一个是脱垂的交叉导管。 第二，偏转引导导管用于提供用于将折叠装置引导到二尖瓣环的下瓣区域的适当位置的装置。 然后使用屈光装置在二尖瓣环的亚瓣膜区域进行肿瘤。 第四，通过打浆装置展开一个可成形的线性保持夹，以便将复制的纸巾保持在复杂的形式中。 可形成的线性保持器通过与保持器推动器结合起作用的打浆装置的夹爪形成为反向的“C”夹。