公开(公告)号：US11129827B2

公开(公告)日：2021-09-28

申请号：US16431632

申请日：2019-06-04

Applicant: Abide Therapeutics, Inc.

Inventor： Cheryl A. Grice ,  Justin S. Cisar ,  Katharine K. Duncan ,  Yu Feng ,  John J. M. Wiener ,  Olivia D. Weber

IPC: A61K31/496 ,  A61K31/506 ,  A61P25/04

Abstract: Provided herein are compounds and pharmaceutical compositions comprising said compounds useful as modulators of MAGL and/or FAAH. The subject compounds and compositions are useful for the treatment of pain and neurological disorders.

公开(公告)号：US10350205B2

公开(公告)日：2019-07-16

申请号：US15919113

申请日：2018-03-12

Applicant: ABIDE THERAPEUTICS, INC.

Inventor： Cheryl A. Grice ,  Justin S. Cisar ,  Katharine K. Duncan ,  Yu Feng ,  John J. M. Wiener ,  Olivia D. Weber

IPC: A61K31/496 ,  A61K31/506 ,  A61P25/04

Abstract: Provided herein are compounds and pharmaceutical compositions comprising said compounds useful as modulators of MAGL and/or FAAH. The subject compounds and compositions are useful for the treatment of pain and neurological disorders.

公开(公告)号：US10266497B2

公开(公告)日：2019-04-23

申请号：US15986747

申请日：2018-05-22

Applicant: ABIDE THERAPEUTICS, INC.

Inventor： Cheryl A. Grice ,  John J. M. Wiener ,  Olivia D. Weber ,  Katharine K. Duncan

IPC: C07D231/14 ,  C07D401/06 ,  C07D403/12 ,  C07D413/12 ,  C07D417/12 ,  C07D417/14 ,  C07D403/06 ,  C07D487/04 ,  C07D471/10 ,  C07D451/02 ,  C07D491/048 ,  C07D401/12 ,  C07D519/00 ,  C07D403/14 ,  C07D413/14

Abstract: Provided herein are pyrazole compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of monoacylglycerol lipase (MAGL). Furthermore, the subject compounds and compositions are useful for the treatment of pain.