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1.发明授权公开(公告)号：US09771589B2
公开(公告)日：2017-09-26
申请号：US15023284
申请日：2014-09-19
Applicant: Academia Sinica
Inventor： Chiaho Shih , Jyun-Yuan Huang
IPC: C12N15/113 , C12N7/00 , A61K31/7088 , A61K45/06
CPC classification number: C12N15/1131 , A61K31/7088 , A61K45/06 , C12N7/00 , C12N15/113 , C12N2310/113 , C12N2310/141 , C12N2310/531 , C12N2320/30 , C12N2730/10111
Abstract: Methods and pharmaceutical compositions for regulating hepatitis virus replication, involving a miR-130a RNA, a miR-130b RNA, a miR-204 RNA, a miR-1236 RNA, or a combination thereof.
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2.发明申请TREATING HEPATITIS VIRUS INFECTION BY MODULATING MICRORNAS MIR-130A, MIR-130B, MIR-204, OR MIR-1236 有权通过调节MICRORNAS MIR-130A，MIR-130B，MIR-204或MIR-1236来治疗恶性病毒感染公开(公告)号：US20160251661A1
公开(公告)日：2016-09-01
申请号：US15023284
申请日：2014-09-19
Applicant: ACADEMIA SINICA
Inventor： Chiaho Shih , Jyun-Yuan Huang
IPC: C12N15/113 , A61K45/06 , A61K31/7088
CPC classification number: C12N15/1131 , A61K31/7088 , A61K45/06 , C12N7/00 , C12N15/113 , C12N2310/113 , C12N2310/141 , C12N2310/531 , C12N2320/30 , C12N2730/10111
Abstract: Methods and pharmaceutical compositions for regulating hepatitis virus replication, involving a miR-130a RNA, a miR-130b RNA, a miR-204 RNA, a miR-1236 RNA, or a combination thereof.
Abstract translation: 涉及miR-130a RNA，miR-130b RNA，miR-204RNA，miR-1236 RNA或其组合的用于调节肝炎病毒复制的方法和药物组合物。
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3.发明申请TREATING DISEASES ASSOCIATED WITH PGC1-ALPHA BY MODULATING MICRORNAS MIR-130A AND MIR-130B 审中-公开通过调节MICRORNAS MIR-130A和MIR-130B与PGC1-ALPHA相关的治疗疾病公开(公告)号：US20160244755A1
公开(公告)日：2016-08-25
申请号：US15023300
申请日：2014-09-19
Applicant: Chiaho SHIH , Jyun-Yuan HUANG , ACADEMIA SINICA;
Inventor： Chiaho Shih , Jyun-Yuan Huang
IPC: C12N15/113
CPC classification number: C12N15/1131 , A61K31/7088 , A61K45/06 , C12N7/00 , C12N15/113 , C12N2310/113 , C12N2310/141 , C12N2310/531 , C12N2320/30 , C12N2730/10111
Abstract: Methods of regulating PGC1α and/or PGC1β, or treating diseases associated with PGC1α and/or PGC1β using a miR-130a RNA, miR-130b RNA, or a combination thereof, or using an antagomiR of miR-130a, an antagomiR of miR-130b, or both, which can be in the form of microRNA sponge or a locked nucleic acid (LNA).
Abstract translation: 调节PGC1α和/或PGC1β的方法，或使用miR-130a RNA，miR-130b RNA或其组合治疗与PGC1α和/或PGC1β相关的疾病，或使用miR-130a的antagomiR，miR- 130b或两者，其可以是微RNA海绵或锁定核酸（LNA）的形式。
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