公开(公告)号：US20230347075A1

公开(公告)日：2023-11-02

申请号：US17780596

申请日：2020-11-17

Applicant: AMGEN INC.

Inventor： Ali Nekouzadeh ,  Mehran Mojarrad ,  Joshua Tamsky ,  Paul Daniel Faucher ,  Scott R. Gibson ,  Kimberly Sepulveda ,  Sheldon B. Moberg

IPC: A61M5/48 ,  A61M5/158 ,  A61M5/315

CPC classification number: A61M5/482 ,  A61M5/158 ,  A61M5/31576

Abstract: A drug delivery device includes a housing, a container disposed in the housing, a drive mechanism, a needle assembly, a fluid flow path, and a vortex flow adapter. The container contains a medicament which is urged out of the container by the drive mechanism. The needle assembly has a needle and/or a cannula to deliver the medicament from the container. The fluid flow path fluidically connects the container and the needle assembly. The vortex flow adapter is disposed within or defines at least a portion of the fluid flow path, and is adapted to urge the medicament to flow in a vortex pattern.

公开(公告)号：US20240082502A1

公开(公告)日：2024-03-14

申请号：US17767463

申请日：2020-10-07

Applicant: AMGEN INC.

Inventor： Ali Nekouzadeh ,  Carl Conrath ,  Kimberly Sepulveda ,  Jimmie L. Ward

IPC: A61M5/315 ,  A61M5/20

CPC classification number: A61M5/31578 ,  A61M5/2033

Abstract: A drug delivery device may include a housing having an opening, a drug storage container, a plunger rod, and a drive mechanism. The drug storage container may have an inner surface at least partially defining a drug storage chamber and an outer surface defining an outer diameter. The drug storage container may further include a plunger stopper and a delivery member having an insertion end configured to extend at least partially through the opening during a delivery state. The drive mechanism may be activatable to drive the plunger stopper in a distal direction to expel a drug from the drug storage container through the delivery member. The drive mechanism may have an inner surface with an inner diameter greater than the outer diameter of the outer surface of the drug storage container.