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公开(公告)号:US20160083470A1
公开(公告)日:2016-03-24
申请号:US14866105
申请日:2015-09-25
Applicant: AMGEN INC.
Inventor: Tara ARVEDSON , Gregory DYAS , James B. ROTTMAN , Barbra SASU , Xiao-juan BI , Grace Ki Jeong LEE , Jackie Z. SHENG
IPC: C07K16/28 , A61K38/18 , A61K39/395
CPC classification number: C07K16/28 , A61K38/1816 , A61K39/3955 , A61K2039/505 , C07K2317/21 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/70 , C07K2317/76 , G01N33/6872 , G01N33/90 , G01N2800/00
Abstract: Compositions for treating disorders of iron homeostasis are provided. More particularly, anti-ferroportin antibodies, compositions containing such antibodies, corresponding nucleic acids, vectors and host cells, and methods of making such antibodies are provided.
Abstract translation: 提供了用于治疗铁体内平衡障碍的组合物。 更具体地,提供抗铁绿蛋白抗体,含有此类抗体的组合物,相应的核酸,载体和宿主细胞,以及制备此类抗体的方法。