公开(公告)号：US10350152B2

公开(公告)日：2019-07-16

申请号：US15739534

申请日：2016-06-15

Applicant: AMOREPACIFIC CORPORATION

Inventor： Bum-Ho Bin ,  Eun-Gyung Cho ,  Eun-Jeong Choi ,  Sungtae Kim ,  Suhyeon Choi ,  Taeryong Lee

IPC: A61K8/49 ,  A61K8/60 ,  A61K8/73 ,  A61K9/00 ,  A61K9/06 ,  A61K9/16 ,  A61K9/20 ,  A61K9/48 ,  A61K31/18 ,  A61K47/06 ,  A61K47/10 ,  A61K47/14 ,  A61K47/22 ,  A61K47/42 ,  A61Q19/02 ,  G01N33/50 ,  A61K31/4178

Abstract: Disclosed in the present specification are: a skin whitening composition having a skin whitening effect by controlling the secretion of exosomes to be secreted from melanocytes; and a method for screening for materials having a skin whitening effect. The skin whitening composition can promote apoptosis of melanocytes by inhibiting the amount of secretion of exosomes to be secreted from melanocytes, and consequently inhibits the generation of melanin through the apoptosis of melanocytes, thereby exhibiting a skin whitening effect.