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公开(公告)号：US09775870B2
公开(公告)日：2017-10-03
申请号：US15093089
申请日：2016-04-07
Applicant: AMOREPACIFIC CORPORATION
Inventor： Jun Seong Park , Hye Yoon Park , Dong Hyun Kim , Eun Jeong Moon , Ji Hye Chung , Jae Kyoung Lee , Duck Hee Kim , Han Kon Kim
IPC: A61K36/00 , A61K36/185 , A61K36/28 , A61K36/287 , A61K36/428 , A61K36/232 , A61K36/45 , A61K36/732 , A61K36/8945 , A61K36/78 , A23L33/105
CPC classification number: A61K36/185 , A23L33/105 , A23V2002/00 , A61K36/232 , A61K36/28 , A61K36/287 , A61K36/428 , A61K36/45 , A61K36/732 , A61K36/78 , A61K36/8945
Abstract: The present invention relates to an extract of a processed herbal medicinal plant and a composition for skin external application which contains the extract. More specifically, the composition for skin external application contains an extract of processed herbal medicinal plant, prepared through a method comprising the steps of: (a) processing an herbal medicinal plant by a process of boiling, steaming, roasting, baking or heating the medicinal plant or a combination of two or more of these processes; (b) obtaining an extract of the processed medicinal plant. The composition shows an improved antioxidant effect.
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2.发明授权Method of external skin application of composition containing red pine root extract 有权含有红松提取物的组合物的外用皮肤应用方法公开(公告)号：US08828456B2
公开(公告)日：2014-09-09
申请号：US13756227
申请日：2013-01-31
Applicant: Amorepacific Corporation
Inventor： Ho Sik Rho , Eun Joo Kim , Ga Young Cho , Hye Yoon Park , Ji Seong Kim , Duck Hee Kim , Han Kon Kim
Abstract: The present invention relates to a composition for skin external application containing a pine root extract. More specifically, the composition for skin external application according to the present invention contains, as an active ingredient, a pine root extract which shows various effects, including eliminating free radicals, protecting the cell membrane from damage by UV radiation, inhibiting the production of reactive oxygen species caused by UV radiation, inhibiting the reduction in the expression of superoxide dismutase (SOD) and catalase caused by UV radiation, stimulating the production of HSP70 to protect cells, inhibiting MMP-2 biosynthesis caused by UV radiation, inducing the expression of SIRT1 gene that restores DNA damage, and inducing the expression of LMNA1 gene that maintains the structure of the nuclear membrane. Ultimately, the composition of the present invention prevents skin aging.
Abstract translation: 本发明涉及含有松根提取物的皮肤外用组合物。 更具体地，根据本发明的皮肤外用组合物含有作为活性成分的松果提取物，其显示各种效果，包括消除自由基，保护细胞膜免受紫外线辐射的损伤，抑制反应性的生成 由紫外线引起的氧物质，抑制由紫外线辐射引起的超氧化物歧化酶（SOD）和过氧化氢酶的表达的降低，刺激HSP70的产生以保护细胞，抑制由UV辐射引起的MMP-2生物合成，诱导SIRT1的表达 基因，其恢复DNA损伤，并诱导维持核膜结构的LMNA1基因的表达。 最终，本发明的组合物可防止皮肤老化。
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3.发明申请METHOD OF EXTERNAL SKIN APPLICATION OF COMPOSITION CONTAINING RED PINE ROOT EXTRACT 有权含有红皮酚提取物的组合物外用皮肤应用方法公开(公告)号：US20130129849A1
公开(公告)日：2013-05-23
申请号：US13756227
申请日：2013-01-31
Applicant: AMOREPACIFIC CORPORATION
Inventor： Ho Sik RHO , Eun Joo Kim , Ga Young Cho , Hye Yoon Park , Ji Seong Kim , Duck Hee Kim , Han Kon Kim
Abstract: The present invention relates to a composition for skin external application containing a pine root extract. More specifically, the composition for skin external application according to the present invention contains, as an active ingredient, a pine root extract which shows various effects, including eliminating free radicals, protecting the cell membrane from damage by UV radiation, inhibiting the production of reactive oxygen species caused by UV radiation, inhibiting the reduction in the expression of superoxide dismutase (SOD) and catalase caused by UV radiation, stimulating the production of HSP70 to protect cells, inhibiting MMP-2 biosynthesis caused by UV radiation, inducing the expression of SIRT1 gene that restores DNA damage, and inducing the expression of LMNA1 gene that maintains the structure of the nuclear membrane. Ultimately, the composition of the present invention prevents skin aging.
Abstract translation: 本发明涉及含有松根提取物的皮肤外用组合物。 更具体地，根据本发明的皮肤外用组合物含有作为活性成分的松果提取物，其显示各种效果，包括消除自由基，保护细胞膜免受紫外线辐射的损伤，抑制反应性的生成 由紫外线引起的氧物质，抑制由紫外线辐射引起的超氧化物歧化酶（SOD）和过氧化氢酶的表达的降低，刺激HSP70的产生以保护细胞，抑制由UV辐射引起的MMP-2生物合成，诱导SIRT1的表达 基因，其恢复DNA损伤，并诱导维持核膜结构的LMNA1基因的表达。 最终，本发明的组合物可防止皮肤老化。
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