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1.发明授权Cosmetic compositoin containing a rubus coreanus extract for diminishing skin wrinkles 有权含有芦荟提取物的化妆品组合物用于减少皮肤皱纹公开(公告)号：US09198945B2
公开(公告)日：2015-12-01
申请号：US13778176
申请日：2013-02-27
Applicant: AMOREPACIFIC CORPORATION
Inventor： Dong Hyun Kim , Jun Seong Park , Sun Hye Yu , Dae Hyuk Kweon , Hyun Ju Koh , Won Seok Park , Duck Hee Kim , Han Kon Kim
Abstract: The present invention relates to a cosmetic composition containing a Rubus coreanus extract as an active ingredient, and more particularly to a cosmetic composition containing an extract from Rubus coreanus processed by traditional oriental medicinal processing technology, in which the Rubus coreanus extract has an excellent effect of reducing skin wrinkles by inhibiting the formation of SNARE complexes and the release of a neurotransmitter. The cosmetic composition has excellent stability in formulations compared to conventional products for reducing skin wrinkles and exhibit effects similar to Botox which has been used to reduce skin wrinkles, thereby greatly reducing skin wrinkles without causing adverse effects.
Abstract translation: 本发明涉及一种含有芦荟提取物作为活性成分的化妆品组合物，更具体地说，涉及一种含有通过传统东方药物加工技术加工的木薯提取物的提取物的化妆品组合物，其中木槿提取物具有优异的效果 通过抑制SNARE复合物的形成和释放神经递质来减少皮肤皱纹。 与用于减少皮肤皱纹的常规产品相比，化妆品组合物具有优异的稳定性，并且具有类似于用于减少皮肤皱纹的肉毒杆菌毒素的效果，从而大大减少皮肤皱纹而不引起不良反应。
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2.发明申请COSMETIC COMPOSITOIN CONTAINING A RUBUS COREANUS EXTRACT FOR DIMINISHING SKIN WRINKLES 有权化妆品组合物，含有皮肤皱纹的皱纹提取物公开(公告)号：US20130171282A1
公开(公告)日：2013-07-04
申请号：US13778176
申请日：2013-02-27
Applicant: Amorepacific Corporation
Inventor： Dong Hyun Kim , Jun Seong Park , Sun Hye Yu , Dae Hyuk Kweon , Hyun Ju Koh , Won Seok Park , Duck Hee Kim , Han Kon Kim
IPC: A61K36/73
Abstract: The present invention relates to a cosmetic composition containing a Rubus coreanus extract as an active ingredient, and more particularly to a cosmetic composition containing an extract from Rubus coreanus processed by traditional oriental medicinal processing technology, in which the Rubus coreanus extract has an excellent effect of reducing skin wrinkles by inhibiting the formation of SNARE complexes and the release of a neurotransmitter. The cosmetic composition has excellent stability in formulations compared to conventional products for reducing skin wrinkles and exhibit effects similar to Botox which has been used to reduce skin wrinkles, thereby greatly reducing skin wrinkles without causing adverse effects.
Abstract translation: 本发明涉及一种含有芦荟提取物作为活性成分的化妆品组合物，更具体地说，涉及一种含有通过传统东方药物加工技术加工的木薯提取物的提取物的化妆品组合物，其中木槿提取物具有优异的效果 通过抑制SNARE复合物的形成和释放神经递质来减少皮肤皱纹。 与用于减少皮肤皱纹的常规产品相比，化妆品组合物具有优异的稳定性，并且具有类似于用于减少皮肤皱纹的肉毒杆菌毒素的效果，从而大大减少皮肤皱纹而不引起不良反应。
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公开(公告)号：US09775870B2
公开(公告)日：2017-10-03
申请号：US15093089
申请日：2016-04-07
Applicant: AMOREPACIFIC CORPORATION
Inventor： Jun Seong Park , Hye Yoon Park , Dong Hyun Kim , Eun Jeong Moon , Ji Hye Chung , Jae Kyoung Lee , Duck Hee Kim , Han Kon Kim
IPC: A61K36/00 , A61K36/185 , A61K36/28 , A61K36/287 , A61K36/428 , A61K36/232 , A61K36/45 , A61K36/732 , A61K36/8945 , A61K36/78 , A23L33/105
CPC classification number: A61K36/185 , A23L33/105 , A23V2002/00 , A61K36/232 , A61K36/28 , A61K36/287 , A61K36/428 , A61K36/45 , A61K36/732 , A61K36/78 , A61K36/8945
Abstract: The present invention relates to an extract of a processed herbal medicinal plant and a composition for skin external application which contains the extract. More specifically, the composition for skin external application contains an extract of processed herbal medicinal plant, prepared through a method comprising the steps of: (a) processing an herbal medicinal plant by a process of boiling, steaming, roasting, baking or heating the medicinal plant or a combination of two or more of these processes; (b) obtaining an extract of the processed medicinal plant. The composition shows an improved antioxidant effect.
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Patent Agency Ranking
4.发明授权Soil microorganism, novel oxidoreductase separated from the soil microorganism, gene encoding the oxidoreductase, and method for producing aglycones using the microorganism, the oxidoreductase and the gene 有权土壤微生物，从土壤微生物分离的新型氧化还原酶，编码氧化还原酶的基因，以及使用微生物，氧化还原酶和基因产生糖苷配基的方法公开(公告)号：US09394562B2
公开(公告)日：2016-07-19
申请号：US14588790
申请日：2015-01-02
Applicant: AMOREPACIFIC CORPORATION , SNU R&DB Foundation
Inventor： Jun Seong Park , Duck Hee Kim , Han Kon Kim , Eun Mi Kim , Byung Gee Kim
CPC classification number: C12P33/20 , C12N1/20 , C12N9/0004 , C12P17/06 , C12P19/02 , C12P33/00 , C12R1/41 , Y02P20/52
Abstract: The present invention relates to the novel Rhizobium sp. GIN611 KCTC11708BP or to cell extracts thereof, to a novel oxidoreductase which exhibits a glycolytic activity, to a gene encoding the oxidoreductase, to a recombinant strain comprising recombinant vector proteins or to an expression vector encoding recombinant proteins, and to a method for the glycolysis of natural products using same as a biocatalyst. The present invention also relates to a method for producing aglycones from a variety of natural products using same. The novel oxidoreductase separated from the novel microorganism of the present invention does not belong to a glucosidase group but belongs to an oxidoreductase group, and has a glycolytic activity for natural products. The novel oxidoreductase oxidizes the sugar in the aglycones of natural products, thereby producing a variety of aglycones.
Abstract translation: 本发明涉及新根瘤菌属（Rhizobium sp。） GIN611KCTC11708BP或其细胞提取物，对具有糖酵解活性的新型氧化还原酶，与编码氧化还原酶的基因相连，包含重组载体蛋白的重组菌株或编码重组蛋白的表达载体，以及糖酵解方法 使用与生物催化剂相同的天然产物。 本发明还涉及使用它们的各种天然产物制备糖苷配基的方法。 从本发明的新型微生物分离的新型氧化还原酶不属于葡萄糖苷酶基团，属于氧化还原酶基团，对天然产物具有糖酵解活性。 新型氧化还原酶氧化天然产物的糖苷配基中的糖，从而产生各种糖苷配基。
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公开(公告)号：US20160016984A1
公开(公告)日：2016-01-21
申请号：US14807971
申请日：2015-07-24
Applicant: AMOREPACIFIC CORPORATION
Inventor： Jun Seong Park , Dong Hyun Kim , Eun Jeong Moon , Sun Hye Yu , Eun Joo Kim , Duck Hee Kim , Han Kon Kim , Myung Kyoo Kim
CPC classification number: B01D11/0215 , C07D407/04
Abstract: Provided is a pressure-cycling type of extraction device comprising: an extraction unit for accommodating and extracting an extraction target substance; a compression unit for increasing the pressure inside the extraction unit; and a decompression unit for decreasing the pressure inside the extraction unit; wherein the pressure inside the extraction unit is increased and decreased by alternately operating the compression unit and the decompression unit, and the extraction unit comprises a bubbling nozzle for supplying bubbles into the extraction target substance. Further provided is a pressure-cycling type of extraction method in which a compression process and a decompression process are carried out alternately, and compositions produced by the method. The extraction device and method allow low temperature extraction, permit outstanding extraction efficiency and can prevent colour changes, olfactory changes and thermal denaturation of the extraction target substance.
Abstract translation: 提供一种压力循环型提取装置，包括：提取单元，用于容纳和提取提取目标物质; 用于增加提取单元内的压力的压缩单元; 以及用于降低提取单元内的压力的减压单元; 其中，通过交替地操作压缩单元和减压单元，提取单元内的压力增加和减少，并且提取单元包括用于向提取目标物质中提供气泡的鼓泡喷嘴。 进一步提供了一种压力循环型提取方法，其中交替进行压缩过程和减压过程，以及通过该方法制备的组合物。 提取装置和方法允许低温提取，提供优异的提取效率，并可以防止提取目标物质的颜色变化，嗅觉变化和热变性。
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公开(公告)号：US09682030B2
公开(公告)日：2017-06-20
申请号：US14450349
申请日：2014-08-04
Applicant: AMOREPACIFIC CORPORATION
Inventor： Sun Sang Kwon , Myeong Hun Yeom , Duck Hee Kim , Han Kon Kim , Nok Hyun Park , Soo Mi Ahn
CPC classification number: A61K8/73 , A61K8/97 , A61K2800/74 , A61K2800/782 , A61Q19/007 , A61Q19/02 , A61Q19/08
Abstract: Disclosed is a method for preparing polysaccharides of green tea, and more particularly to a method for preparing polysaccharides of green tea comprising the steps of: a) removing chlorophyll and a low molecular weight polyphenol from green tea powder using a solvent; b) hot-water extracting a water-soluble active ingredient from the green tea residue of step a); and c) separating the polysaccharides of green tea from the hot-water extract of step b) by ultrafiltration and ethanol precipitation. Also, the present invention relates to a cosmetic composition for skin whitening, moisturization and anti-wrinkle effects comprising the polysaccharides of green tea as an effective ingredient.
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7.发明授权Method of external skin application of composition containing red pine root extract 有权含有红松提取物的组合物的外用皮肤应用方法公开(公告)号：US08828456B2
公开(公告)日：2014-09-09
申请号：US13756227
申请日：2013-01-31
Applicant: Amorepacific Corporation
Inventor： Ho Sik Rho , Eun Joo Kim , Ga Young Cho , Hye Yoon Park , Ji Seong Kim , Duck Hee Kim , Han Kon Kim
Abstract: The present invention relates to a composition for skin external application containing a pine root extract. More specifically, the composition for skin external application according to the present invention contains, as an active ingredient, a pine root extract which shows various effects, including eliminating free radicals, protecting the cell membrane from damage by UV radiation, inhibiting the production of reactive oxygen species caused by UV radiation, inhibiting the reduction in the expression of superoxide dismutase (SOD) and catalase caused by UV radiation, stimulating the production of HSP70 to protect cells, inhibiting MMP-2 biosynthesis caused by UV radiation, inducing the expression of SIRT1 gene that restores DNA damage, and inducing the expression of LMNA1 gene that maintains the structure of the nuclear membrane. Ultimately, the composition of the present invention prevents skin aging.
Abstract translation: 本发明涉及含有松根提取物的皮肤外用组合物。 更具体地，根据本发明的皮肤外用组合物含有作为活性成分的松果提取物，其显示各种效果，包括消除自由基，保护细胞膜免受紫外线辐射的损伤，抑制反应性的生成 由紫外线引起的氧物质，抑制由紫外线辐射引起的超氧化物歧化酶（SOD）和过氧化氢酶的表达的降低，刺激HSP70的产生以保护细胞，抑制由UV辐射引起的MMP-2生物合成，诱导SIRT1的表达 基因，其恢复DNA损伤，并诱导维持核膜结构的LMNA1基因的表达。 最终，本发明的组合物可防止皮肤老化。
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8.发明申请METHOD OF EXTERNAL SKIN APPLICATION OF COMPOSITION CONTAINING RED PINE ROOT EXTRACT 有权含有红皮酚提取物的组合物外用皮肤应用方法公开(公告)号：US20130129849A1
公开(公告)日：2013-05-23
申请号：US13756227
申请日：2013-01-31
Applicant: AMOREPACIFIC CORPORATION
Inventor： Ho Sik RHO , Eun Joo Kim , Ga Young Cho , Hye Yoon Park , Ji Seong Kim , Duck Hee Kim , Han Kon Kim
Abstract: The present invention relates to a composition for skin external application containing a pine root extract. More specifically, the composition for skin external application according to the present invention contains, as an active ingredient, a pine root extract which shows various effects, including eliminating free radicals, protecting the cell membrane from damage by UV radiation, inhibiting the production of reactive oxygen species caused by UV radiation, inhibiting the reduction in the expression of superoxide dismutase (SOD) and catalase caused by UV radiation, stimulating the production of HSP70 to protect cells, inhibiting MMP-2 biosynthesis caused by UV radiation, inducing the expression of SIRT1 gene that restores DNA damage, and inducing the expression of LMNA1 gene that maintains the structure of the nuclear membrane. Ultimately, the composition of the present invention prevents skin aging.
Abstract translation: 本发明涉及含有松根提取物的皮肤外用组合物。 更具体地，根据本发明的皮肤外用组合物含有作为活性成分的松果提取物，其显示各种效果，包括消除自由基，保护细胞膜免受紫外线辐射的损伤，抑制反应性的生成 由紫外线引起的氧物质，抑制由紫外线辐射引起的超氧化物歧化酶（SOD）和过氧化氢酶的表达的降低，刺激HSP70的产生以保护细胞，抑制由UV辐射引起的MMP-2生物合成，诱导SIRT1的表达 基因，其恢复DNA损伤，并诱导维持核膜结构的LMNA1基因的表达。 最终，本发明的组合物可防止皮肤老化。
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