公开(公告)号：US20220024915A1

公开(公告)日：2022-01-27

申请号：US17279422

申请日：2019-09-27

Applicant: ACUCELA INC.

Inventor： Mark W. ORME ,  Edison S. ZUNIGA ,  Vladimir A. KUKSA ,  Russell Stuart CRAFT ,  Eduardo Moreno SAVEEDRA ,  Johannes Wilhelm Georg MEISSNER ,  Jacobus Antonius Joseph den HARTOG ,  Albert Cornelis DROS

IPC: C07D471/04 ,  C07D487/04

Abstract: Provided herein are compounds and methods of use thereof for the modulation of VAP-1 activity.

公开(公告)号：US20210387975A1

公开(公告)日：2021-12-16

申请号：US17279382

申请日：2019-09-27

Applicant: ACUCELA INC.

Inventor： Mark W. ORME ,  Edison S. ZUNIGA ,  Vladimir A. KUKSA ,  Russell Stuart CRAFT ,  Eduardo Moreno SAVEEDRA ,  Johannes Wilhelm Georg MEISSNER ,  Jacobus Antonius Joseph den HARTOG ,  Albert Cornelis DROS

IPC: C07D413/12 ,  C07D263/56 ,  C07D277/64 ,  C07D263/58 ,  C07D277/82 ,  C07D261/20 ,  C07D235/08 ,  C07D413/04 ,  C07D491/107 ,  C07D249/18

Abstract: Provided herein are compounds and methods of use thereof for the modulation of VAP-1 activity.

公开(公告)号：US20230295140A1

公开(公告)日：2023-09-21

申请号：US18201715

申请日：2023-05-24

Applicant: Acucela Inc.

Inventor： Mark W. ORME ,  Edison S. ZUNIGA ,  Vladimir A. KUKSA ,  Russell Stuart CRAFT ,  Eduardo Moreno SAVEEDRA ,  Johannes Wilhelm Georg MEISSNER ,  Jacobus Antonius Joseph den HARTOG ,  Albert Cornelis DROS

IPC: C07D413/12 ,  C07D235/08 ,  C07D249/18 ,  C07D261/20 ,  C07D263/56 ,  C07D263/58 ,  C07D277/64 ,  C07D277/82 ,  C07D413/04 ,  C07D491/107

CPC classification number: C07D413/12 ,  C07D235/08 ,  C07D249/18 ,  C07D261/20 ,  C07D263/56 ,  C07D263/58 ,  C07D277/64 ,  C07D277/82 ,  C07D413/04 ,  C07D491/107

Abstract: Provided herein are compounds and methods of use thereof for the modulation of VAP-1 activity.