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公开(公告)号：US10435466B2
公开(公告)日：2019-10-08
申请号：US15521514
申请日：2015-10-27
Applicant: Agency for Science, Technology and Research
Inventor： Cheng-i Wang , Hsueh Ling Janice Oh , Siok Ping Yeo , Yun Pei Sharon Goh
IPC: C07K16/28 , A61K39/395
Abstract: Anti-TIM-3 antibodies are disclosed, as well as pharmaceutical compositions comprising such antibodies, and uses and methods using the same, such as in the treatment of cancer or infectious disease or T-cell dysfunctional disorders. Bispecific antibodies against TIM-3 and other targets are also disclosed, with a preferred embodiment of a bispecific antibody against TIM-3 and CD3.
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公开(公告)号：US20170319690A1
公开(公告)日：2017-11-09
申请号：US15623679
申请日：2017-06-15
Applicant: Agency for Science, Technology and Research
Inventor： Cheng-i Wang , Hsueh Ling Janice Oh , Siok Ping Yeo
IPC: A61K39/395 , G01N33/574 , A61K45/06 , G01N33/53 , C07K14/705 , C07K16/28
CPC classification number: A61K39/3955 , A61K39/395 , A61K45/06 , A61K2039/505 , C07K14/70532 , C07K16/2827 , C07K2317/21 , C07K2317/33 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/567 , C07K2317/622 , C07K2317/76 , C07K2317/92 , C07K2319/30 , G01N33/53 , G01N33/57484 , G01N2800/52 , Y02A50/41 , Y02A50/412
Abstract: Anti-PD-L1 antibodies are disclosed. Also disclosed are pharmaceutical compositions comprising such antibodies, and uses and methods using the same.
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公开(公告)号：US20170240633A1
公开(公告)日：2017-08-24
申请号：US15521685
申请日：2015-10-27
Applicant: Agency for Science, Technology and Research
Inventor： Cheng-i Wang , Hsueh Ling Janice Oh , Siok Ping Yeo , Yun Pei Sharon Goh
CPC classification number: C07K16/2803 , C07K16/2809 , C07K16/3061 , C07K16/468 , C07K2317/21 , C07K2317/31 , C07K2317/565 , C07K2317/622 , C07K2317/732 , C07K2317/92
Abstract: Anti-TIM-3 antibodies are disclosed, as well as pharmaceutical compositions comprising such antibodies, and uses and methods using the same, such as in the treatment of cancer, infectious diseases, or T-cell dysfunctional disorders. Bispecific antibodies against TIM-3 and other targets are also disclosed, with preferred embodiment of a bispecific antibody against TIM-3 and CD3.
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公开(公告)号：US11534489B2
公开(公告)日：2022-12-27
申请号：US16597586
申请日：2019-10-09
Applicant: Agency for Science, Technology and Research
Inventor： Cheng-i Wang , Hsueh Ling Janice Oh , Siok Ping Yeo
IPC: A61K39/395 , C07K16/28 , A61K45/06 , C07K14/705 , G01N33/53 , G01N33/574 , A61K39/00
Abstract: Anti-PD-L1 antibodies are disclosed. Also disclosed are pharmaceutical compositions comprising such antibodies, and uses and methods using the same.
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公开(公告)号：US10517949B2
公开(公告)日：2019-12-31
申请号：US15542023
申请日：2016-01-04
Applicant: Agency for Science, Technology and Research
Inventor： Cheng-i Wang , Hsueh Ling Janice Oh , Siok Ping Yeo
IPC: A61K39/395 , G01N33/574 , C07K14/705 , G01N33/53 , A61K45/06 , C07K16/28 , A61K39/00
Abstract: Anti-PD-L1 antibodies are disclosed. Also disclosed are pharmaceutical compositions comprising such antibodies, and methods of using such antibodies to restore T-cell function in T-cells exhibiting T-cell exhaustion or T-cell anergy.
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Patent Agency Ranking
公开(公告)号：US10280224B2
公开(公告)日：2019-05-07
申请号：US15521434
申请日：2015-10-27
Applicant: Agency for Science, Technology and Research
Inventor： Cheng-i Wang , Hsueh Ling Janice Oh , Siok Ping Yeo , Jianrong Lionel Low , Hwee Ching Tan
Abstract: Anti-PD-1 antibodies are disclosed. Also disclosed are pharmaceutical compositions comprising such antibodies, and uses and methods using the same.
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公开(公告)号：US20170313774A1
公开(公告)日：2017-11-02
申请号：US15521434
申请日：2015-10-27
Applicant: Agency for Science, Technology and Research
Inventor： Cheng-i Wang , Hsueh Ling Janice Oh , Siok Ping Yeo , Jianrong Lionel Low , Hwee Ching Tan
CPC classification number: C07K16/2818 , A61K2039/505 , C07K16/005 , C07K2317/31 , C07K2317/33 , C07K2317/51 , C07K2317/515 , C07K2317/565 , C07K2317/92
Abstract: Anti-PD-1 antibodies are disclosed. Also disclosed are pharmaceutical compositions comprising such antibodies, and uses and methods using the same.
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公开(公告)号：US20180002423A1
公开(公告)日：2018-01-04
申请号：US15542023
申请日：2016-01-04
Applicant: Agency for Science, Technology and Research
Inventor： Cheng-i Wang , Hsueh Ling Janice Oh , Siok Ping Yeo
IPC: C07K16/28 , A61K39/395
CPC classification number: A61K39/3955 , A61K39/395 , A61K45/06 , A61K2039/505 , C07K14/70532 , C07K16/2827 , C07K2317/21 , C07K2317/33 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/567 , C07K2317/622 , C07K2317/76 , C07K2317/92 , C07K2319/30 , G01N33/53 , G01N33/57484 , G01N2800/52 , Y02A50/41 , Y02A50/412
Abstract: Anti-PD-L1 antibodies are disclosed. Also disclosed are pharmaceutical compositions comprising such antibodies, and methods of using such antibodies to restore T-cell function in T-cells exhibiting T-cell exhaustion or T-cell anergy.
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公开(公告)号：US20170306016A1
公开(公告)日：2017-10-26
申请号：US15521514
申请日：2015-10-27
Applicant: Agency for Science, Technology and Research
Inventor： Cheng-i Wang , Hsueh Ling Janice Oh , Siok Ping Yeo , Yun Pei Sharon Goh
IPC: C07K16/28 , A61K39/395
CPC classification number: C07K16/2803 , A61K39/395 , C07K16/28 , C07K16/2809 , C07K2317/31 , C07K2317/622
Abstract: Anti-TIM-3 antibodies are disclosed, as well as pharmaceutical compositions comprising such antibodies, and uses and methods using the same, such as in the treatment of cancer or infectious disease or T-cell dysfunctional disorders. Bispecific antibodies against TIM-3 and other targets are also disclosed, with a preferred embodiment of a bispecific antibody against TIM-3 and CD3.
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公开(公告)号：US09771425B2
公开(公告)日：2017-09-26
申请号：US15495048
申请日：2017-04-24
Applicant: Agency for Science, Technology and Research
Inventor： Cheng-i Wang , Hsueh Ling Janice Oh , Siok Ping Yeo , Jianrong Lionel Low , Hwee Ching Tan
IPC: C07K16/28
CPC classification number: C07K16/2818 , A61K2039/505 , C07K16/005 , C07K2317/31 , C07K2317/33 , C07K2317/51 , C07K2317/515 , C07K2317/565 , C07K2317/92
Abstract: Anti-PD-1 antibodies are disclosed. Also disclosed are pharmaceutical compositions comprising such antibodies, and uses and methods using the same.
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