IMMEDIATE RELEASE PHARMACEUTICAL GRANULE COMPOSITIONS AND A CONTINUOUS PROCESS FOR MAKING THEM
    3.
    发明申请
    IMMEDIATE RELEASE PHARMACEUTICAL GRANULE COMPOSITIONS AND A CONTINUOUS PROCESS FOR MAKING THEM 审中-公开
    立即发布药物颗粒组合物及其连续制备方法

    公开(公告)号:US20070009592A1

    公开(公告)日:2007-01-11

    申请号:US11276577

    申请日:2006-03-06

    IPC分类号: A61K9/20

    摘要: An immediate or fast release pharmaceutical granule composition comprising at least one drug (i) classifiable as Class II or Class IV of the Biopharmaceutical Classification System, wherein the said drug constitutes at least about 0.5% by weight and no more than 50% by weight of the composition, and further comprising (ii) a first excipient being a dextrin-containing compound and a second excipient (iii) selected from the group consisting of polyethylene glycols and polypropylene glycols having weight number molecular weights between about 300 and 10,000, glycerol, propylene glycol and glycerides.

    摘要翻译: 一种立即或快速释放的药物颗粒组合物,其包含至少一种可分类为生物药物分类系统的II类或IV类的药物(i),其中所述药物占至少约0.5重量%且不超过50重量% 并且还包含(ii)第一赋形剂,其为含糊精的化合物和选自重量数分子量在约300至10,000之间的聚乙二醇和聚丙二醇的第二赋形剂(iii),甘油,丙烯 乙二醇和甘油酯。

    Immediate release pharmaceutical granule compositions and a continuous process for making them
    4.
    发明申请
    Immediate release pharmaceutical granule compositions and a continuous process for making them 审中-公开
    立即释放药物颗粒组合物和制备它们的连续方法

    公开(公告)号:US20050058705A1

    公开(公告)日:2005-03-17

    申请号:US10933674

    申请日:2004-09-03

    IPC分类号: A61K9/16 A61K9/48 A61K9/20

    摘要: An immediate or fast release pharmaceutical granule composition comprising at least one drug (i) classifiable as Class II or Class IV of the Biopharmaceutical Classification System, wherein the said drug constitutes at least about 0.5% by weight and no more than 50% by weight of the composition, the said composition further comprising (ii) a first excipient being a dextrin-containing compound and a second excipient (iii) being selected from the group consisting of polyethylene glycols and polypropylene glycols having weight number molecular weights between about 300 and 10,000, glycerol, propylene glycol and glycerides.

    摘要翻译: 一种立即或快速释放的药物颗粒组合物,其包含至少一种可分类为生物药物分类系统的II类或IV类的药物(i),其中所述药物占至少约0.5重量%且不超过50重量% 所述组合物还包含(ii)第一赋形剂,其为含糊精的化合物和第二赋形剂(iii),其选自重量数分子量在约300至10,000之间的聚乙二醇和聚丙二醇, 甘油,丙二醇和甘油酯。

    Controlled delivery system for bioactive substances
    5.
    发明申请
    Controlled delivery system for bioactive substances 审中-公开
    生物活性物质的控制输送系统

    公开(公告)号:US20060003006A1

    公开(公告)日:2006-01-05

    申请号:US10529537

    申请日:2003-09-24

    IPC分类号: A61K9/24

    摘要: A biologically active composite solid shaped article comprising: (a) an outer layer, and (b) an inner core filling the said outer layer and comprising: at least a biologically active ingredient, and an excipient comprising at least a hydrophilic cellulose polymer and an amphiphilic material in the form of a blend with the said hydrophilic cellulose polymer, the weight ratio of the hydrophilic cellulose polymer to the amphiphilic material being from 0.2:1 to 0.6:1, provides improved sustained release of the biologically active ingredient.

    摘要翻译: 一种生物活性复合固体成形制品,其包含:(a)外层,和(b)填充所述外层的内芯,并且包含:至少一种生物活性成分和至少包含亲水性纤维素聚合物和 与亲水性纤维素聚合物共混形式的亲水性材料,亲水性纤维素聚合物与两性物质的重量比为0.2:1至0.6:1,提供了生物活性成分的改善的持续释放。