-
公开(公告)号:US4350687A
公开(公告)日:1982-09-21
申请号:US234448
申请日:1980-02-10
申请人: Allan Lipton , Nancy Kepner
发明人: Allan Lipton , Nancy Kepner
摘要: A purified cell growth factor is produced which comprises a substantially purified glycoproteinaceous factor from platelets which has mitogenic activity toward transformed cells, a molecular weight of 3,000-5,000 daltons and a pI of 7.8-8.3. The growth factor is stable to treatment with 4M guanidine hydrochloride, and is heat labile when treated at 100.degree. C. for 5 minutes.
摘要翻译: 产生纯化的细胞生长因子,其包含来自血小板的基本上纯化的糖蛋白因子,其对转化细胞具有促有丝分裂活性,分子量为3,000-5,000道尔顿,pI为7.8-8.3。 生长因子对于4M盐酸胍处理稳定,在100℃下处理5分钟时热不稳定。