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公开(公告)号：US09790190B2
公开(公告)日：2017-10-17
申请号：US15593064
申请日：2017-05-11
Applicant: Array BioPharma Inc. , Genentech, Inc.
Inventor： David Askin , Chong Han , Jonathan W. Lane , Travis Remarchuk , Sagar Shakya , C. Gregory Sowell , Keith L. Spencer , Peter J. Stengel
IPC: C07D403/00 , C07D239/42 , C07D403/04
CPC classification number: C07D239/42 , C07D239/30 , C07D239/70 , C07D403/04
Abstract: The invention provides processes for preparing a compound of formula I and salts thereof, wherein R1 is defined herein, and compounds and intermediates of said formula.
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公开(公告)号：US20170247337A1
公开(公告)日：2017-08-31
申请号：US15593064
申请日：2017-05-11
Applicant: Array BioPharma Inc. , Genentech, Inc.
Inventor： David Askin , Chong Han , Jonathan W. Lane , Travis Remarchuk , Sagar Shakya , C. Gregory Sowell , Keith L. Spencer , Peter J. Stengel
IPC: C07D239/42
CPC classification number: C07D239/42 , C07D239/30 , C07D239/70 , C07D403/04
Abstract: The invention provides processes for preparing a compound of formula I and salts thereof, wherein R1 is defined herein, and compounds and intermediates of said formula.
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公开(公告)号：US20150152067A1
公开(公告)日：2015-06-04
申请号：US14401087
申请日：2013-05-17
Applicant: Array BioPharma Inc. , Genentech, Inc.
Inventor： David Askin , Chong Han , Jonathan W. Lane , Travis Remarchuk , Sagar Shakya , C. Gregory Sowell , Keith L. Spencer , Peter J. Stengel
IPC: C07D239/42 , C07D239/70
CPC classification number: C07D239/42 , C07D239/30 , C07D239/70 , C07D403/04
Abstract: The invention provides processes for preparing a compound of formula I and salts thereof, wherein R1 is defined herein, and compounds and intermediates of said formula.
Abstract translation: 本发明提供制备式I化合物及其盐的方法，其中R 1在本文中定义，以及所述式的化合物和中间体。
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公开(公告)号：US20180258054A1
公开(公告)日：2018-09-13
申请号：US15782620
申请日：2017-10-12
Applicant: Array BioPharma Inc. , Genentech, Inc.
Inventor： David Askin , Chong Han , Jonathan W. Lane , Travis Remarchuk , Sagar Shakya , C. Gregory Sowell , Keith L. Spencer , Peter J. Stengel
IPC: C07D239/42 , C07D403/04
CPC classification number: C07D239/42 , C07D239/30 , C07D239/70 , C07D403/04
Abstract: The invention provides processes for preparing a compound of formula I and salts thereof, wherein R1 is defined herein, and compounds and intermediates of said formula.
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公开(公告)号：US09676730B2
公开(公告)日：2017-06-13
申请号：US15204715
申请日：2016-07-07
Applicant: Array BioPharma Inc. , Genentech, Inc.
Inventor： David Askin , Chong Han , Jonathan W. Lane , Travis Remarchuk , Sagar Shakya , C. Gregory Sowell , Keith L. Spencer , Peter J. Stengel
IPC: C07D239/70 , C07D239/42 , C07D239/30 , C07D403/04
CPC classification number: C07D239/42 , C07D239/30 , C07D239/70 , C07D403/04
Abstract: The invention provides processes for preparing a compound of formula I and salts thereof, wherein R1 is defined herein, and compounds and intermediates of said formula.
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Patent Agency Ranking
公开(公告)号：US09416110B2
公开(公告)日：2016-08-16
申请号：US14401087
申请日：2013-05-17
Applicant: Array BioPharma Inc. , Genentech, Inc.
Inventor： David Askin , Chong Han , Jonathan W. Lane , Travis Remarchuk , Sagar Shakya , C. Gregory Sowell , Keith L. Spencer , Peter J. Stengel
IPC: C07D239/02 , C07D239/42 , C07D239/30 , C07D403/04 , C07D239/70
CPC classification number: C07D239/42 , C07D239/30 , C07D239/70 , C07D403/04
Abstract: The invention provides processes for preparing a compound of formula I and salts thereof, wherein R1 is defined herein, and compounds and intermediates of said formula.
Abstract translation: 本发明提供制备式I化合物及其盐的方法，其中R 1在本文中定义，以及所述式的化合物和中间体。
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公开(公告)号：US20160318877A1
公开(公告)日：2016-11-03
申请号：US15204715
申请日：2016-07-07
Applicant: Array BioPharma Inc. , Genentech, Inc.
Inventor： David Askin , Chong Han , Jonathan W. Lane , Travis Remarchuk , Sagar Shakya , C. Gregory Sowell , Keith L. Spencer , Peter J. Stengel
IPC: C07D239/42
CPC classification number: C07D239/42 , C07D239/30 , C07D239/70 , C07D403/04
Abstract: The invention provides processes for preparing a compound of formula I and salts thereof, wherein R1 is defined herein, and compounds and intermediates of said formula.
Abstract translation: 和其盐，其中R1如本文所定义，以及所述式的化合物和中间体。
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公开(公告)号：US10793541B2
公开(公告)日：2020-10-06
申请号：US16271215
申请日：2019-02-08
Applicant: Exelixis, Inc. , Genentech, Inc.
Inventor： Sriram Naganathan , Nathan Guz , Matthew Pfeiffer , C. Gregory Sowell , Tracy Bostick , Jason Yang , Amit Srivastava , Neel Kumar Anand
IPC: C07D471/04 , C07D401/04 , C07D498/04
Abstract: Disclosed herein is a process of making a compound of formula I The compound of formula I is an inhibitor of MEK and thus can be used to treat cancer.
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公开(公告)号：US11414396B2
公开(公告)日：2022-08-16
申请号：US17003570
申请日：2020-08-26
Applicant: Exelixis, Inc. , Genentech, Inc.
Inventor： Sriram Naganathan , Nathan Guz , Matthew Pfeiffer , C. Gregory Sowell , Tracy Bostick , Jason Yang , Amit Srivastava , Neel Kumar Anand
IPC: C07D401/04 , C07D498/04
Abstract: Disclosed herein is a process of making a compound of formula I The compound of formula I is an inhibitor of MEK and thus can be used to treat cancer.
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公开(公告)号：US10239858B2
公开(公告)日：2019-03-26
申请号：US15686333
申请日：2017-08-25
Applicant: Exelixis, Inc. , Genentech, Inc.
Inventor： Sriram Naganathan , Nathan Guz , Matthew Pfeiffer , C. Gregory Sowell , Tracy Bostick , Jason Yang , Amit Srivastava , Neel Kumar Anand
IPC: C07D401/04 , C07D498/04
Abstract: Disclosed herein is a process of making a compound of formula I The compound of formula I is an inhibitor of MEK and thus can be used to treat cancer.
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