-
公开(公告)号：US10793541B2
公开(公告)日：2020-10-06
申请号：US16271215
申请日：2019-02-08
Applicant: Exelixis, Inc. , Genentech, Inc.
Inventor： Sriram Naganathan , Nathan Guz , Matthew Pfeiffer , C. Gregory Sowell , Tracy Bostick , Jason Yang , Amit Srivastava , Neel Kumar Anand
IPC: C07D471/04 , C07D401/04 , C07D498/04
Abstract: Disclosed herein is a process of making a compound of formula I The compound of formula I is an inhibitor of MEK and thus can be used to treat cancer.
-
公开(公告)号：US20190185447A1
公开(公告)日：2019-06-20
申请号：US16271215
申请日：2019-02-08
Applicant: Exelixis, Inc. , Genentech, Inc.
Inventor： Sriram Naganathan , Nathan Guz , Matthew Pfeiffer , C. Gregory Sowell , Tracy Bostick , Jason Yang , Amit Srivastava , Neel Kumar Anand
IPC: C07D401/04 , C07D498/04
Abstract: Disclosed herein is a process of making a compound of formula I The compound of formula I is an inhibitor of MEK and thus can be used to treat cancer.
-
公开(公告)号：US11414396B2
公开(公告)日：2022-08-16
申请号：US17003570
申请日：2020-08-26
Applicant: Exelixis, Inc. , Genentech, Inc.
Inventor： Sriram Naganathan , Nathan Guz , Matthew Pfeiffer , C. Gregory Sowell , Tracy Bostick , Jason Yang , Amit Srivastava , Neel Kumar Anand
IPC: C07D401/04 , C07D498/04
Abstract: Disclosed herein is a process of making a compound of formula I The compound of formula I is an inhibitor of MEK and thus can be used to treat cancer.
-
公开(公告)号：US10239858B2
公开(公告)日：2019-03-26
申请号：US15686333
申请日：2017-08-25
Applicant: Exelixis, Inc. , Genentech, Inc.
Inventor： Sriram Naganathan , Nathan Guz , Matthew Pfeiffer , C. Gregory Sowell , Tracy Bostick , Jason Yang , Amit Srivastava , Neel Kumar Anand
IPC: C07D401/04 , C07D498/04
Abstract: Disclosed herein is a process of making a compound of formula I The compound of formula I is an inhibitor of MEK and thus can be used to treat cancer.
-
公开(公告)号：US11597699B2
公开(公告)日：2023-03-07
申请号：US16853043
申请日：2020-04-20
Applicant: Exelixis, Inc.
Inventor： Naing Aay , Neel Kumar Anand , Charles M. Blazey , Owen Joseph Bowles , Joerg Bussenius , Simona Costanzo , Jeffry Kimo Curtis , Steven Charles DeFina , Larisa Dubenko , Anagha Abhijit Joshi , Abigail R. Kennedy , Angie Inyoung Kim , Elena S. Koltun , Jean-Claire Limun Manalo , Csaba J. Peto , Kenneth D. Rice , Tsze H. Tsang
IPC: C07D205/04 , C07D205/06 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/12 , C07D409/06 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04 , C07D401/04 , C07D409/12
Abstract: Disclosed are compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors and are useful in the treatment of proliferative diseases, such as cancer. Also disclosed are pharmaceutical compositions containing such compounds as well as methods of using the compounds and compositions of the invention in the treatment of cancer.
-
Patent Agency Ranking
公开(公告)号：US20170166523A9
公开(公告)日：2017-06-15
申请号：US14615079
申请日：2015-02-05
Applicant: Exelixis, Inc.
Inventor： Naing Aay , Neel Kumar Anand , Charles M. Blazey , Owen Joseph Bowles , Joerg Bussenius , Simona Costanzo , Jeffry Kimo Curtis , Steven Charles DeFina , Larisa Dubenko , Anagha Abhijit Joshi , Abigail R. Kennedy , Angie Inyoung Kim , Elena S. Koltun , Jean-Claire Limun Manalo , Csaba J. Peto , Kenneth D. Rice , Tsze H. Tsang
IPC: C07D205/04 , C07D403/06 , C07D401/14 , C07D471/04 , C07D401/04 , C07D403/04 , C07D409/06
CPC classification number: C07D205/04 , C07D205/06 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/12 , C07D409/06 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04
Abstract: Disclosed are compounds of Formula I: and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors and are useful in the treatment of proliferative diseases, such as cancer. Also disclosed are pharmaceutical compositions containing such compounds as well as methods of using the compounds and compositions of the invention in the treatment of cancer.
-
公开(公告)号：US20200031770A1
公开(公告)日：2020-01-30
申请号：US16597607
申请日：2019-10-09
Applicant: Exelixis, Inc.
Inventor： Naing Aay , Neel Kumar Anand , Charles M. Blazey , Owen Joseph Bowles , Joerg Bussenlus , Simona Costanzo , Jeffry Kimo Curtis , Steven Charles DeFina , Larisa Dubenko , Anagha Abhijit Joshi , Abigall R. Kennedy , Angle Inyoung Kim , Elena S. Koltun , Jean-Claire Limun Manalo , Csaba J. Peto , Kenneth D. Rice , Tsze H. Tsang
IPC: C07D205/04 , C07D205/06 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/12 , C07D409/06 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04 , C07D401/04
Abstract: Disclosed are compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors and are useful in the treatment of proliferative diseases, such as cancer. Also disclosed are pharmaceutical compositions containing such compounds as well as methods of using the compounds and compositions of the invention in the treatment of cancer.
-
公开(公告)号：US20150141399A1
公开(公告)日：2015-05-21
申请号：US14615079
申请日：2015-02-05
Applicant: Exelixis, Inc.
Inventor： Naing Aay , Neel Kumar Anand , Charles M. Blazey , Owen Joseph Bowles , Joerg Bussenius , Simona Costanzo , Jeffry Kimo Curtis , Steven Charles DeFina , Larisa Dubenko , Anagha Abhijit Joshi , Abigail R. Kennedy , Angie Inyoung Kim , Elena S. Koltun , Jean-Claire Limun Manalo , Csaba J. Peto , Kenneth D. Rice , Tsze H. Tsang
IPC: C07D205/04 , C07D403/06 , C07D401/14 , C07D471/04 , C07D401/04 , C07D403/04 , C07D409/06
CPC classification number: C07D205/04 , C07D205/06 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/12 , C07D409/06 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04
Abstract: Disclosed are compounds of Formula I: and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors and are useful in the treatment of proliferative diseases, such as cancer. Also disclosed are pharmaceutical compositions containing such compounds as well as methods of using the compounds and compositions of the invention in the treatment of cancer.
Abstract translation: 公开了式I的化合物及其药学上可接受的盐和溶剂化物。 这些化合物是MEK抑制剂，可用于治疗增殖性疾病如癌症。 还公开了含有这些化合物的药物组合物以及使用本发明化合物和组合物治疗癌症的方法。
-
公开(公告)号：US20250100966A1
公开(公告)日：2025-03-27
申请号：US18672226
申请日：2024-05-23
Applicant: Exelixis, Inc.
Inventor： Naing Aay , Neel Kumar Anand , Charles M. Blazey , Owen Joseph Bowles , Joerg Bussenius , Simona Costanzo , Jeffry Kimo Curtis , Steven Charles DeFina , Larisa Dubenko , Anagha Abhijit Joshi , Abigail R Kennedy , Angie Inyoung Kim , Elena S. Koltun , Jean-Claire Limun Manalo , Csaba J. Peto , Kenneth D. Rice , Tsze H. Tsang
IPC: C07D205/04 , C07D205/06 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/12 , C07D409/06 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04
Abstract: Disclosed am compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors and am useful in the treatment of proliferative diseases, such as cancer. Also disclosed are pharmaceutical compositions containing such compounds as well as methods of using the compounds and compositions of the invention in the treatment of cancer.
-
公开(公告)号：US20200283383A1
公开(公告)日：2020-09-10
申请号：US16853043
申请日：2020-04-20
Applicant: Exelixis, Inc.
Inventor： Naing Aay , Neel Kumar Anand , Charles M. Blazey , Owen Joseph Bowles , Joerg Bussenius , Simona Costanzo , Jeffry Kimo Curtis , Steven Charles DeFina , Larisa Dubenko , Anagha Abhijit Joshi , Abigail R. Kennedy , Angie Inyoung Kim , Elena S. Koltun , Jean-Claire Limun Manalo , Csaba J. Peto , Kenneth D. Rice , Tsze H. Tsang
IPC: C07D205/04 , C07D205/06 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/12 , C07D409/06 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04 , C07D401/04
Abstract: Disclosed are compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors and are useful in the treatment of proliferative diseases, such as cancer. Also disclosed are pharmaceutical compositions containing such compounds as well as methods of using the compounds and compositions of the invention in the treatment of cancer.
-
-
-
-
-
-
-
-
-
Search Results
12
records
(took 0.026 seconds)
