Composite poly (aryl ether ketone) membranes, their preparation and use thereof

    公开(公告)号:US11673099B2

    公开(公告)日:2023-06-13

    申请号:US17737211

    申请日:2022-05-05

    Applicant: Avanpore LLC

    Inventor: Benjamin Bikson

    Abstract: Disclosed is the preparation of composite membranes formed by a tailored selective chemical modification of an ultra-thin nanoporous surface layer of a semi-crystalline mesoporous poly (aryl ether ketone) membrane with graded density pore structure. The composite separation layer is synthesized in situ on the poly (aryl ether ketone) substrate surface and is covalently linked to the surface of the semi-crystalline mesoporous poly (aryl ether ketone) membrane. Hollow fiber configuration is the preferred embodiment of forming the functionalized the poly (aryl ether ketone) membranes. Composite poly (aryl ether ketone) membranes of the present invention are particularly useful for a broad range of fluid separation applications, including organic solvent ultrafiltration and nanofiltration to separate and recover active pharmaceutical ingredients.

    Composite poly (aryl ether ketone) membranes, their preparation and use thereof

    公开(公告)号:US11786871B2

    公开(公告)日:2023-10-17

    申请号:US18123591

    申请日:2023-03-20

    Applicant: Avanpore LLC

    Inventor: Benjamin Bikson

    Abstract: Disclosed is the preparation of composite membranes formed by a tailored selective chemical modification of an ultra-thin nanoporous surface layer of a semi-crystalline mesoporous poly (aryl ether ketone) membrane with graded density pore structure. The composite separation layer is synthesized in situ on the poly (aryl ether ketone) substrate surface and is covalently linked to the surface of the semi-crystalline mesoporous poly (aryl ether ketone) membrane. Hollow fiber configuration is the preferred embodiment of forming the functionalized the poly (aryl ether ketone) membranes. Composite poly (aryl ether ketone) membranes of the present invention are particularly useful for a broad range of fluid separation applications, including organic solvent ultrafiltration and nanofiltration to separate and recover active pharmaceutical ingredients.

    Preparation of mesoporous poly (aryl ether ketone) articles and use thereof

    公开(公告)号:US11629239B2

    公开(公告)日:2023-04-18

    申请号:US17966172

    申请日:2022-10-14

    Applicant: Avanpore LLC

    Inventor: Benjamin Bikson

    Abstract: Mesoporous poly (aryl ether ketone) articles are formed from blends of poly (aryl ether ketones) with pore forming additives by melt processing, and can be in the form of a monofilament, disc, film, microcapillary or other complex shapes. The method of formation provides for preparation of poly (aryl ether ketone) articles with high degree of surface area and uniform nanometer pore size. The preferred poly (aryl ether ketone)s are poly (ether ketone) and poly (ether ether ketone). The mesoporous articles formed by the method of the present invention are useful for a broad range of applications, including molecular separations and organic solvent filtration.

    Composite Poly (Aryl Ether Ketone) Membranes, Their Preparation And Use Thereof

    公开(公告)号:US20230059166A1

    公开(公告)日:2023-02-23

    申请号:US17737211

    申请日:2022-05-05

    Applicant: Avanpore LLC

    Inventor: Benjamin Bikson

    Abstract: Disclosed is the preparation of composite membranes formed by a tailored selective chemical modification of an ultra-thin nanoporous surface layer of a semi-crystalline mesoporous poly (aryl ether ketone) membrane with graded density pore structure. The composite separation layer is synthesized in situ on the poly (aryl ether ketone) substrate surface and is covalently linked to the surface of the semi-crystalline mesoporous poly (aryl ether ketone) membrane. Hollow fiber configuration is the preferred embodiment of forming the functionalized the poly (aryl ether ketone) membranes. Composite poly (aryl ether ketone) membranes of the present invention are particularly useful for a broad range of fluid separation applications, including organic solvent ultrafiltration and nanofiltration to separate and recover active pharmaceutical ingredients.

    Composite Poly (Aryl Ether Ketone) Membranes, Their Preparation And Use Thereof

    公开(公告)号:US20230226500A1

    公开(公告)日:2023-07-20

    申请号:US18123591

    申请日:2023-03-20

    Applicant: Avanpore LLC

    Inventor: Benjamin Bikson

    Abstract: Disclosed is the preparation of composite membranes formed by a tailored selective chemical modification of an ultra-thin nanoporous surface layer of a semi-crystalline mesoporous poly (aryl ether ketone) membrane with graded density pore structure. The composite separation layer is synthesized in situ on the poly (aryl ether ketone) substrate surface and is covalently linked to the surface of the semi-crystalline mesoporous poly (aryl ether ketone) membrane. Hollow fiber configuration is the preferred embodiment of forming the functionalized the poly (aryl ether ketone) membranes. Composite poly (aryl ether ketone) membranes of the present invention are particularly useful for a broad range of fluid separation applications, including organic solvent ultrafiltration and nanofiltration to separate and recover active pharmaceutical ingredients.

    Mesoporous poly (aryl ether ketone) hollow fiber membranes and use thereof in mass transfer processes

    公开(公告)号:US11491464B1

    公开(公告)日:2022-11-08

    申请号:US17836575

    申请日:2022-06-09

    Applicant: Avanpore LLC

    Inventor: Benjamin Bikson

    Abstract: A process for the efficient transfer of molecules between phases employing mesoporous poly (aryl ether ketone) hollow fiber membranes is provided. The method addresses the controlled transfer of reactants into and removal of reaction products from a reaction media and the removal and separation of target molecules from process streams by membrane-assisted liquid-liquid extraction. A number of possible modes of liquid-liquid extraction are possible according to the invention by utilizing porous poly (aryl ether ketone) hollow fiber membranes of Janus-like structure that exhibit a combination of hydrophilic and hydrophobic surface characteristics. The method of the present invention can address the continuous manufacture of chemicals in membrane reactors and is useful for a broad range of separation applications, including separation and recovery of active pharmaceutical ingredients.

    Preparation Of Mesoporous Poly (Aryl Ether Ketone) Articles And Use Thereof

    公开(公告)号:US20230050009A1

    公开(公告)日:2023-02-16

    申请号:US17966172

    申请日:2022-10-14

    Applicant: Avanpore LLC

    Inventor: Benjamin Bikson

    Abstract: Mesoporous poly (aryl ether ketone) articles are formed from blends of poly (aryl ether ketones) with pore forming additives by melt processing, and can be in the form of a monofilament, disc, film, microcapillary or other complex shapes. The method of formation provides for preparation of poly (aryl ether ketone) articles with high degree of surface area and uniform nanometer pore size. The preferred poly (aryl ether ketone)s are poly (ether ketone) and poly (ether ether ketone). The mesoporous articles formed by the method of the present invention are useful for a broad range of applications, including molecular separations and organic solvent filtration.

    Preparation of mesoporous poly (aryl ether ketone) articles and use thereof

    公开(公告)号:US11505671B1

    公开(公告)日:2022-11-22

    申请号:US17740897

    申请日:2022-05-10

    Applicant: Avanpore LLC

    Inventor: Benjamin Bikson

    Abstract: Mesoporous poly (aryl ether ketone) articles are formed from blends of poly (aryl ether ketones) with pore forming additives by melt processing, and can be in the form of a monofilament, disc, film, microcapillary or other complex shapes. The method of formation provides for preparation of poly (aryl ether ketone) articles with high degree of surface area and uniform nanometer pore size. The preferred poly (aryl ether ketone)s are poly (ether ketone) and poly (ether ether ketone). The mesoporous articles formed by the method of the present invention are useful for a broad range of applications, including molecular separations and organic solvent filtration.

    Mesoporous Poly (Aryl Ether Ketone) Hollow Fiber Membranes And Use Thereof In Mass Transfer Processes

    公开(公告)号:US20230219062A1

    公开(公告)日:2023-07-13

    申请号:US18124130

    申请日:2023-03-21

    Applicant: Avanpore LLC

    Inventor: Benjamin Bikson

    Abstract: A process for the efficient transfer of molecules between phases employing mesoporous poly (aryl ether ketone) hollow fiber membranes is provided. The method addresses the controlled transfer of reactants into and removal of reaction products from a reaction media and the removal and separation of target molecules from process streams by membrane-assisted liquid-liquid extraction. A number of possible modes of liquid-liquid extraction are possible according to the invention by utilizing porous poly (aryl ether ketone) hollow fiber membranes of Janus-like structure that exhibit a combination of hydrophilic and hydrophobic surface characteristics. The method of the present invention can address the continuous manufacture of chemicals in membrane reactors and is useful for a broad range of separation applications, including separation and recovery of active pharmaceutical ingredients.

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