利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

7 条记录 (耗时 0.049 秒)

    Nucleic acid molecule comprising a nucleic acid sequence coding for a chemokine, a neuropeptide precursor, or at least one neuropeptide
    7.
    发明申请
    Nucleic acid molecule comprising a nucleic acid sequence coding for a chemokine, a neuropeptide precursor, or at least one neuropeptide 审中-公开
    包含编码趋化因子，神经肽前体或至少一种神经肽的核酸序列的核酸分子

    公开(公告)号：US20080319165A1

    公开(公告)日：2008-12-25

    申请号：US12010221

    申请日：2008-01-22

    申请人： Hans Werner Muller ,  Frank Bosse ,  Mark Gleichmann ,  Clemens Gillen ,  Johannes Auer

    发明人： Hans Werner Muller ,  Frank Bosse ,  Mark Gleichmann ,  Clemens Gillen ,  Johannes Auer

    IPC分类号： C07K7/00 ,  C07K14/00

    CPC分类号： C07K14/522 ,  A61K38/00 ,  A61K48/00

    摘要： The invention concerns a nucleic acid molecule which includes a nucleic acid sequence coding for a chemokine, a neuropeptide precursor or at least one neuropeptide, as well as a host cell which contains this nucleic acid molecule. In addition the invention concerns a polypeptide molecule which functions as chemokine or neuropeptide or contains at least one neuropeptide, as well as fragments thereof which include at least one neuropeptide, and a procedure for the manufacture of the polypeptide molecule or of a fragment thereof. In addition the invention concerns antibodies, demonstration procedures and test-kits as well as pharmaceutical preparations.The purpose on which present invention is based is to make new means available which can be put to use aimed at the diagnosis and/or treatment of diseases which are associated with a defect of the SDF-1 factor or its receptor (CXCR4).

    摘要翻译： 本发明涉及核酸分子，其包括编码趋化因子，神经肽前体或至少一种神经肽的核酸序列，以及含有该核酸分子的宿主细胞。 此外，本发明涉及用作趋化因子或神经肽或含有至少一种神经肽的多肽分子及其包含至少一种神经肽的片段，以及用于制备多肽分子或其片段的方法。 此外，本发明涉及抗体，示范程序和测试试剂盒以及药物制剂。 本发明所基于的目的是提供可用于诊断和/或治疗与SDF-1因子或其受体（CXCR4）的缺陷相关的疾病的新手段。