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公开(公告)号：US11597695B2
公开(公告)日：2023-03-07
申请号：US16340788
申请日：2017-10-11
Applicant: BASF SE
Inventor： Miriam Kolk , Konstantinos Scholinakis , Eike Ulf Mahnke , Lutz Hilterhaus , Volker Winterhoff
Abstract: A method of preparing an ester by reacting a carboxylic acid with a (C1-C36)alcohol in the presence of a catalyst that is suitable for preparing carboxylic acid esters of monomeric carboxylic acids in high yield. The method reduces by-products of the reaction, in particular esters of dimeric, trimeric and/or oligomeric carboxylic acids. The method requires a minimal excess of alcohol and does not require removal of water and/or carboxylic acid ester from the reaction mixture. The method is particularly suitable for the reaction of hydroxyalkylcarboxylic acids and fatty alcohols.
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公开(公告)号：US20130217788A1
公开(公告)日：2013-08-22
申请号：US13768264
申请日：2013-02-15
Applicant: BASF SE
Inventor： Peter Kempers , Rolf Kawa , Stefan Brüning , Jadranka Milardovic , Eike Ulf Mahnke , Heinz-Josef Krüppel , Markus Dierker , Burkhard Beckedahl
CPC classification number: A61K47/10 , A61K8/345 , A61K2800/10 , A61Q19/00
Abstract: Mixtures of Guerbet alcohols, their use in cosmetic and/or pharmaceutical preparations, and also cosmetic and/or pharmaceutical preparations comprising mixtures of Guerbet alcohols are described. Of suitability as petroleum jelly substitute are in particular Guerbet alcohol mixtures with a melting range, measured by differential scanning calorimetry (DSC), between −20° C. and +70° C., where the width of the melting range comprises at least 30 temperature degrees and the maximum of the melting range is 35±10° C. These are obtainable for example by reacting a) 55 to 95% by weight of cetylstearyl alcohol, b) 5 to 45% by weight of fatty alcohols with a chain length of from 8 to 22 carbon atoms and c) optionally an aliphatic diol having at least 3 carbon atoms.
Abstract translation: 描述了Guerbet醇的混合物，它们在化妆品和/或药物制剂中的用途，以及包含Guerbet醇混合物的化妆品和/或药物制剂。 作为凡士林替代品的适用性尤其是在-20℃至+ 70℃之间，通过差示扫描量热法（DSC）测量的熔融范围的格尔伯特醇混合物，其中熔融范围的宽度包括至少30 温度程度和熔化范围的最大值为35±10℃。这些可通过例如使a）55至95重量％的鲸蜡基硬脂醇，b）5至45重量％的具有链长的脂肪醇 8至22个碳原子，和c）任选具有至少3个碳原子的脂族二醇。
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公开(公告)号：US10357569B2
公开(公告)日：2019-07-23
申请号：US15534517
申请日：2015-12-11
Applicant: BASF SE
Inventor： Stefan Busch , Eike Ulf Mahnke , Melina Machado Sincero , Markus Kloeker
Abstract: The present invention relates to a composition containing carbohydrate partial esters, the preparation thereof and products containing the carbohydrate partial esters according to the invention.
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Patent Agency Ranking
公开(公告)号：US09333262B2
公开(公告)日：2016-05-10
申请号：US13768264
申请日：2013-02-15
Applicant: BASF SE
Inventor： Peter Kempers , Rolf Kawa , Stefan Brüning , Jadranka Milardovic , Eike Ulf Mahnke , Heinz-Josef Krüppel , Markus Dierker , Burkhard Beckedahl
CPC classification number: A61K47/10 , A61K8/345 , A61K2800/10 , A61Q19/00
Abstract: Mixtures of Guerbet alcohols, their use in cosmetic and/or pharmaceutical preparations, and also cosmetic and/or pharmaceutical preparations comprising mixtures of Guerbet alcohols are described. Of suitability as petroleum jelly substitute are in particular Guerbet alcohol mixtures with a melting range, measured by differential scanning calorimetry (DSC), between −20° C. and +70° C., where the width of the melting range comprises at least 30 temperature degrees and the maximum of the melting range is 35±10° C. These are obtainable for example by reacting a) 55 to 95% by weight of cetylstearyl alcohol, b) 5 to 45% by weight of fatty alcohols with a chain length of from 8 to 22 carbon atoms and c) optionally an aliphatic diol having at least 3 carbon atoms.
Abstract translation: 描述了Guerbet醇的混合物，它们在化妆品和/或药物制剂中的用途，以及包含Guerbet醇混合物的化妆品和/或药物制剂。 作为凡士林替代品的适用性尤其是在-20℃至+ 70℃之间，通过差示扫描量热法（DSC）测量的熔融范围的格尔伯特醇混合物，其中熔融范围的宽度包括至少30 温度程度和熔化范围的最大值为35±10℃。这些可通过例如使a）55至95重量％的鲸蜡基硬脂醇，b）5至45重量％的具有链长的脂肪醇 8至22个碳原子，和c）任选具有至少3个碳原子的脂族二醇。
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公开(公告)号：US20130217787A1
公开(公告)日：2013-08-22
申请号：US13768243
申请日：2013-02-15
Applicant: BASF SE
Inventor： Markus Dierker , Peter Kempers , Rolf Kawa , Stefan Brüning , Jadranka Milardovic , Burkhard Beckedahl , Eike Ulf Mahnke , Heinz-Josef Krüppel
CPC classification number: A61K8/342 , A61K8/33 , A61K47/08 , A61K2800/10 , A61Q19/00
Abstract: Described herein are mixed ethers and cosmetic and/or pharmaceutical preparations comprising mixed ethers. Certain mixed ethers have a melting range between −25° C. and +70° C., wherein the width of the melting range comprises at least 30 temperature degrees and the maximum of the melting range is 35±10° C. These mixed ethers are obtainable for example by condensation reaction of a) 25 to 90% by weight of unbranched fatty alcohols with a chain length of 12 to 18 carbon atoms; b) 5 to 50% by weight of isostearyl alcohol; c) 0 to 35% by weight of a fatty alcohol with a chain length of 20 and/or 22 carbon atoms; and d) 0 to 25% by weight of a fatty alcohol having 8 and/or 10 carbon atoms.
Abstract translation: 本文描述的是混合醚和包含混合醚的化妆品和/或药物制剂。 某些混合醚的熔点范围为-25℃至+ 70℃，其中熔融范围的宽度包括至少30度的温度，熔融范围的最大值为35±10℃。这些混合醚 可以例如通过a）25至90重量％的链长为12至18个碳原子的非支链脂肪醇的缩合反应获得; b）5至50重量％的异硬脂醇; c）0至35重量％的链长为20和/或22个碳原子的脂肪醇; 和d）0至25重量％的具有8个和/或10个碳原子的脂肪醇。
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公开(公告)号：US20200048180A1
公开(公告)日：2020-02-13
申请号：US16340788
申请日：2017-10-11
Applicant: BASF SE
Inventor： Miriam Kolk , Konstantinos Scholinakis , Eike Ulf Mahnke , Lutz Hilterhaus , Volker Winterhoff
IPC: C07C67/08
Abstract: A method of preparing an ester by reacting a carboxylic acid with a (C1-C36)alcohol in the presence of a catalyst that is suitable for preparing carboxylic acid esters of monomeric carboxylic acids in high yield. The method reduces by-products of the reaction, in particular esters of dimeric, trimeric and/or oligomeric carboxylic acids. The method requires a minimal excess of alcohol and does not require removal of water and/or carboxylic acid ester from the reaction mixture. The method is particularly suitable for the reaction of hydroxyalkylcarboxylic acids and fatty alcohols.
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公开(公告)号：US20170360938A1
公开(公告)日：2017-12-21
申请号：US15534517
申请日：2015-12-11
Applicant: BASF SE
Inventor： Stefan Busch , Eike Ulf Mahnke , Melina Machado Sincero , Markus Kloeker
CPC classification number: A61K47/26 , A23L33/125 , A23V2002/00 , A61K8/361 , A61K8/37 , A61K8/375 , A61K8/60 , A61K47/14 , A61Q19/00
Abstract: The present invention relates to a composition containing carbohydrate partial esters, the preparation thereof and products containing the carbohydrate partial esters according to the invention.
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公开(公告)号：US08993811B2
公开(公告)日：2015-03-31
申请号：US13768243
申请日：2013-02-15
Applicant: BASF SE
Inventor： Markus Dierker , Peter Kempers , Rolf Kawa , Stefan Brüning , Jadranka Milardovic , Burkhard Beckedahl , Eike Ulf Mahnke , Heinz-Josef Krüppel
CPC classification number: A61K8/342 , A61K8/33 , A61K47/08 , A61K2800/10 , A61Q19/00
Abstract: Described herein are mixed ethers and cosmetic and/or pharmaceutical preparations comprising mixed ethers. Certain mixed ethers have a melting range between −25° C. and +70° C., wherein the width of the melting range comprises at least 30 temperature degrees and the maximum of the melting range is 35 ±10° C. These mixed ethers are obtainable for example by condensation reaction of a) 25 to 90% by weight of unbranched fatty alcohols with a chain length of 12 to 19 carbon atoms; b) 5 to 50 by weight of isostearyl alcohol; c) 0 to 35% by weight of a fatty alcohol with a chain length of 20 and/or 22 carbon atoms; and d) 0 to 25% by weight of a fatty alcohol having 8 and/or 10 carbon atoms.
Abstract translation: 本文描述的是混合醚和包含混合醚的化妆品和/或药物制剂。 某些混合醚的熔点范围为-25℃至+ 70℃，其中熔融范围的宽度包括至少30度的温度，熔融范围的最大值为35±10℃。这些混合醚 可以例如通过a）25至90重量％的链长为12至19个碳原子的非支链脂肪醇的缩合反应获得; b）5至50重量份异硬脂醇; c）0至35重量％的链长为20和/或22个碳原子的脂肪醇; 和d）0至25重量％的具有8个和/或10个碳原子的脂肪醇。
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