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公开(公告)号：US09416337B2
公开(公告)日：2016-08-16
申请号：US14047212
申请日：2013-10-07
Applicant: BASF SE
Inventor： Peter Kempers , Ulrich Schörken , Rolf Kawa , Jörg Schwarzer , Thomas Wolf
CPC classification number: C11C3/003 , C12P7/6436
Abstract: The present invention relates to a process for preparing esters from fatty alcohols, in which fatty alcohols and fatty acids are reacted in the presence of an enzyme at a temperature in the range of 30 to 50° C., the water which forms is removed and the reaction is completed under reduced pressure at a temperature of 50 to 80° C.
Abstract translation: 本发明涉及从脂肪醇制备酯的方法，其中脂肪醇和脂肪酸在酶的存在下在30-50℃的温度下反应，除去形成的水和 反应在50至80℃的温度下在减压下完成。
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Patent Agency Ranking
公开(公告)号：US20130217788A1
公开(公告)日：2013-08-22
申请号：US13768264
申请日：2013-02-15
Applicant: BASF SE
Inventor： Peter Kempers , Rolf Kawa , Stefan Brüning , Jadranka Milardovic , Eike Ulf Mahnke , Heinz-Josef Krüppel , Markus Dierker , Burkhard Beckedahl
CPC classification number: A61K47/10 , A61K8/345 , A61K2800/10 , A61Q19/00
Abstract: Mixtures of Guerbet alcohols, their use in cosmetic and/or pharmaceutical preparations, and also cosmetic and/or pharmaceutical preparations comprising mixtures of Guerbet alcohols are described. Of suitability as petroleum jelly substitute are in particular Guerbet alcohol mixtures with a melting range, measured by differential scanning calorimetry (DSC), between −20° C. and +70° C., where the width of the melting range comprises at least 30 temperature degrees and the maximum of the melting range is 35±10° C. These are obtainable for example by reacting a) 55 to 95% by weight of cetylstearyl alcohol, b) 5 to 45% by weight of fatty alcohols with a chain length of from 8 to 22 carbon atoms and c) optionally an aliphatic diol having at least 3 carbon atoms.
Abstract translation: 描述了Guerbet醇的混合物，它们在化妆品和/或药物制剂中的用途，以及包含Guerbet醇混合物的化妆品和/或药物制剂。 作为凡士林替代品的适用性尤其是在-20℃至+ 70℃之间，通过差示扫描量热法（DSC）测量的熔融范围的格尔伯特醇混合物，其中熔融范围的宽度包括至少30 温度程度和熔化范围的最大值为35±10℃。这些可通过例如使a）55至95重量％的鲸蜡基硬脂醇，b）5至45重量％的具有链长的脂肪醇 8至22个碳原子，和c）任选具有至少3个碳原子的脂族二醇。
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公开(公告)号：US08993811B2
公开(公告)日：2015-03-31
申请号：US13768243
申请日：2013-02-15
Applicant: BASF SE
Inventor： Markus Dierker , Peter Kempers , Rolf Kawa , Stefan Brüning , Jadranka Milardovic , Burkhard Beckedahl , Eike Ulf Mahnke , Heinz-Josef Krüppel
CPC classification number: A61K8/342 , A61K8/33 , A61K47/08 , A61K2800/10 , A61Q19/00
Abstract: Described herein are mixed ethers and cosmetic and/or pharmaceutical preparations comprising mixed ethers. Certain mixed ethers have a melting range between −25° C. and +70° C., wherein the width of the melting range comprises at least 30 temperature degrees and the maximum of the melting range is 35 ±10° C. These mixed ethers are obtainable for example by condensation reaction of a) 25 to 90% by weight of unbranched fatty alcohols with a chain length of 12 to 19 carbon atoms; b) 5 to 50 by weight of isostearyl alcohol; c) 0 to 35% by weight of a fatty alcohol with a chain length of 20 and/or 22 carbon atoms; and d) 0 to 25% by weight of a fatty alcohol having 8 and/or 10 carbon atoms.
Abstract translation: 本文描述的是混合醚和包含混合醚的化妆品和/或药物制剂。 某些混合醚的熔点范围为-25℃至+ 70℃，其中熔融范围的宽度包括至少30度的温度，熔融范围的最大值为35±10℃。这些混合醚 可以例如通过a）25至90重量％的链长为12至19个碳原子的非支链脂肪醇的缩合反应获得; b）5至50重量份异硬脂醇; c）0至35重量％的链长为20和/或22个碳原子的脂肪醇; 和d）0至25重量％的具有8个和/或10个碳原子的脂肪醇。
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公开(公告)号：US20140170717A1
公开(公告)日：2014-06-19
申请号：US14047212
申请日：2013-10-07
Applicant: BASF SE
Inventor： Peter Kempers , Ulrich Schörken , Rolf Kawa , Jörg Schwarzer , Thomas Wolf
IPC: C12P7/62
CPC classification number: C11C3/003 , C12P7/6436
Abstract: The present invention relates to a process for preparing esters from fatty alcohols, in which fatty alcohols and fatty acids are reacted in the presence of an enzyme at a temperature in the range of 30 to 50° C., the water which forms is removed and the reaction is completed under reduced pressure at a temperature of 50 to 80° C.
Abstract translation: 本发明涉及从脂肪醇制备酯的方法，其中脂肪醇和脂肪酸在酶的存在下在30-50℃的温度下反应，除去形成的水和 反应在50至80℃的温度下在减压下完成。
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公开(公告)号：US09333262B2
公开(公告)日：2016-05-10
申请号：US13768264
申请日：2013-02-15
Applicant: BASF SE
Inventor： Peter Kempers , Rolf Kawa , Stefan Brüning , Jadranka Milardovic , Eike Ulf Mahnke , Heinz-Josef Krüppel , Markus Dierker , Burkhard Beckedahl
CPC classification number: A61K47/10 , A61K8/345 , A61K2800/10 , A61Q19/00
Abstract: Mixtures of Guerbet alcohols, their use in cosmetic and/or pharmaceutical preparations, and also cosmetic and/or pharmaceutical preparations comprising mixtures of Guerbet alcohols are described. Of suitability as petroleum jelly substitute are in particular Guerbet alcohol mixtures with a melting range, measured by differential scanning calorimetry (DSC), between −20° C. and +70° C., where the width of the melting range comprises at least 30 temperature degrees and the maximum of the melting range is 35±10° C. These are obtainable for example by reacting a) 55 to 95% by weight of cetylstearyl alcohol, b) 5 to 45% by weight of fatty alcohols with a chain length of from 8 to 22 carbon atoms and c) optionally an aliphatic diol having at least 3 carbon atoms.
Abstract translation: 描述了Guerbet醇的混合物，它们在化妆品和/或药物制剂中的用途，以及包含Guerbet醇混合物的化妆品和/或药物制剂。 作为凡士林替代品的适用性尤其是在-20℃至+ 70℃之间，通过差示扫描量热法（DSC）测量的熔融范围的格尔伯特醇混合物，其中熔融范围的宽度包括至少30 温度程度和熔化范围的最大值为35±10℃。这些可通过例如使a）55至95重量％的鲸蜡基硬脂醇，b）5至45重量％的具有链长的脂肪醇 8至22个碳原子，和c）任选具有至少3个碳原子的脂族二醇。
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公开(公告)号：US20130217787A1
公开(公告)日：2013-08-22
申请号：US13768243
申请日：2013-02-15
Applicant: BASF SE
Inventor： Markus Dierker , Peter Kempers , Rolf Kawa , Stefan Brüning , Jadranka Milardovic , Burkhard Beckedahl , Eike Ulf Mahnke , Heinz-Josef Krüppel
CPC classification number: A61K8/342 , A61K8/33 , A61K47/08 , A61K2800/10 , A61Q19/00
Abstract: Described herein are mixed ethers and cosmetic and/or pharmaceutical preparations comprising mixed ethers. Certain mixed ethers have a melting range between −25° C. and +70° C., wherein the width of the melting range comprises at least 30 temperature degrees and the maximum of the melting range is 35±10° C. These mixed ethers are obtainable for example by condensation reaction of a) 25 to 90% by weight of unbranched fatty alcohols with a chain length of 12 to 18 carbon atoms; b) 5 to 50% by weight of isostearyl alcohol; c) 0 to 35% by weight of a fatty alcohol with a chain length of 20 and/or 22 carbon atoms; and d) 0 to 25% by weight of a fatty alcohol having 8 and/or 10 carbon atoms.
Abstract translation: 本文描述的是混合醚和包含混合醚的化妆品和/或药物制剂。 某些混合醚的熔点范围为-25℃至+ 70℃，其中熔融范围的宽度包括至少30度的温度，熔融范围的最大值为35±10℃。这些混合醚 可以例如通过a）25至90重量％的链长为12至18个碳原子的非支链脂肪醇的缩合反应获得; b）5至50重量％的异硬脂醇; c）0至35重量％的链长为20和/或22个碳原子的脂肪醇; 和d）0至25重量％的具有8个和/或10个碳原子的脂肪醇。
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