公开(公告)号：US20240367143A1

公开(公告)日：2024-11-07

申请号：US18653214

申请日：2024-05-02

Applicant: BIO-RAD LABORATORIES, INC.

Inventor： SHAWN DARNALL ,  BRIAN PANGANIBAN ,  DANNI WANG ,  CHRISTOPHER BELISLE ,  ZACHARY CLAUSS

IPC: B01J20/04 ,  B01D15/08 ,  B01J20/28 ,  B01J20/282 ,  B01J20/30 ,  B01J20/32 ,  B01J20/34

Abstract: Provided herein is a chromatography media composed of a porous solid substrate (such as a membrane, metal, or metallic alloy) that is coated with hydroxyapatite (IA). Also provided is a chromatography media comprising a HA-coated substrate and uses thereof. Thus this disclosure provides a chromatography media composed of a porous solid substrate (such as a membrane, metal, or metallic alloy) that is coated with I-IA. Also provided is a chromatography media comprising a HA-coated substrate and uses thereof. Methods of preparing the HA-coated substrate are also provided.