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公开(公告)号:US20230089459A1
公开(公告)日:2023-03-23
申请号:US17788534
申请日:2020-12-22
申请人: BIOPHYTIS , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , NSERM (INSTITUT NATIONAL DE LA SANTE ET DELA RECHERCHE ME'DICALE) , BORBONNE UNIVERSITE
发明人: Laurence DINAN , René LAFONT , Pierre DILDA , Serge CAMELO , Valérie FONTAINE , Christine BALDUCCI , Elodie MONTEIRO , Louis GUIBOUT , Mathilde LATIL , José-Alain SAHEL , Stanislas VEILLET
IPC分类号: C07C211/21 , C07D265/30 , C07D211/32 , C07D273/06 , C07D207/06 , C07D307/36 , A61P27/02
摘要: Disclosed is chemical compounds C that are derivatives of norbixin and have tropism for the eye, and are intended to be used in the treatment of eye diseases in mammals, in particular in the context of altering the retinal pigment epithelium and more particularly in the context of age-related macular degeneration (AMD) and Stargardt's disease.