-
公开(公告)号：US10981879B2
公开(公告)日：2021-04-20
申请号：US16145345
申请日：2018-09-28
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Andrew Quoc Viet , Nicholas R. Wurtz
IPC: C07D249/18 , C07D249/16 , C07D471/04 , C07D487/04 , A61K31/437 , A61K31/7064
Abstract: The present invention provides compounds of Formula (I): wherein A, X and Y are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are myeloperoxidase (MPO) inhibitors and/or eosinophil peroxidase (EPX) inhibitors, which may be used as medicaments.
-
公开(公告)号：US20190031623A1
公开(公告)日：2019-01-31
申请号：US16145345
申请日：2018-09-28
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Andrew Quoc Viet , Nicholas R. Wurtz
IPC: C07D249/16 , A61K31/7064 , C07D471/04 , C07D487/04 , A61K31/437
Abstract: The present invention provides compounds of Formula (I): wherein A, X and Y are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are myeloperoxidase (MPO) inhibitors and/or eosinophil peroxidase (EPX) inhibitors, which may be used as medicaments.
-
公开(公告)号：US11186544B2
公开(公告)日：2021-11-30
申请号：US16619956
申请日：2018-06-08
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Nicholas R. Wurtz , Pravin Sudhakar Shirude , Andrew Quoc Viet
IPC: C07D211/98 , C07D401/04 , C07D401/10 , C07D401/12 , C07D405/10 , C07D409/10 , C07D413/10 , C07D413/12 , C07D413/14 , C07D417/12
Abstract: The disclosure relates to compounds of formula (I), which are formyl peptide 2 (FPR2) receptor agonists and/or formyl peptide 1 (FPR1) receptor agonists. The disclosure also provides compositions and methods of using the compounds, for example, for the treatment of atherosclerosis, heart failure, chronic obstructive pulmonary disease (COPD), and related diseases.
-
Patent Agency Ranking
公开(公告)号：US09920075B2
公开(公告)日：2018-03-20
申请号：US15510168
申请日：2015-09-09
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Nicholas R. Wurtz , Andrew Quoc Viet , Scott A. Shaw , Benjamin P. Vokits , Ellen K. Kick , Meriah Neissel Valente , Andrew K. Dilger , Kumar Balashanmuga Pabbisetty , Sutjano Jusuf
IPC: A61K31/519 , C07D519/00 , C07D471/04 , C07D487/04 , A61K31/437
CPC classification number: C07D519/00 , A61K31/437 , A61K31/519 , C07D471/04 , C07D487/04
Abstract: The present invention provides compounds of Formula (I): wherein A and R1 are each as defined in the specification, and compositions comprising any of such novel compounds. These compounds are myeloperoxidase (MPO) inhibitors and/or eosinophil peroxidase (EPX) inhibitors, which may be used as medicaments.
-
公开(公告)号：US20170247396A1
公开(公告)日：2017-08-31
申请号：US15510168
申请日：2015-09-09
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Nicholas R. Wurtz , Andrew Quoc Viet , Scott A. Shaw , Benjamin P. Vokits , Ellen K. Kick , Meriah Neissel Valente , Andrew K. Dilger , Kumar Balashanmuga Pabbisetty , Sutjano Jusuf
IPC: C07D519/00 , C07D487/04 , C07D471/04
CPC classification number: C07D519/00 , A61K31/437 , A61K31/519 , C07D471/04 , C07D487/04
Abstract: The present invention provides compounds of Formula (I): wherein A and R1 are each as defined in the specification, and compositions comprising any of such novel compounds. These compounds are myeloperoxidase (MPO) inhibitors and/or eosinophil peroxidase (EPX) inhibitors, which may be used as medicaments.
-
公开(公告)号：US10316035B2
公开(公告)日：2019-06-11
申请号：US15756373
申请日：2016-08-30
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Andrew Quoc Viet , Nicholas Ronald Wurtz , Scott A. Shaw , Ellen K. Kick , Andrew K. Dilger , Kumar Balashanmuga Pabbisetty
IPC: C07D471/04
Abstract: The present invention provides compounds of Formula (I): wherein A, Y and R1 are each as defined in the specification, and compositions comprising any of such novel compounds. These compounds are myeloperoxidase (MPO) inhibitors and/or eosinophil peroxidase (EPX) inhibitors, which may be used as medicaments.
-
公开(公告)号：US20180244671A1
公开(公告)日：2018-08-30
申请号：US15756373
申请日：2016-08-30
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Andrew Quoc Viet , Nicholas Ronald Wurtz , Scott A. Shaw , Ellen K. Kick , Andrew K. Dilger , Kumar Balashanmuga Pabbisetty
IPC: C07D471/04
CPC classification number: C07D471/04
Abstract: The present invention provides compounds of Formula (I): wherein A, Y and R1 are each as defined in the specification, and compositions comprising any of such novel compounds. These compounds are myeloperoxidase (MPO) inhibitors and/or eosinophil peroxidase (EPX) inhibitors, which may be used as medicaments.
-
公开(公告)号：US20170247343A1
公开(公告)日：2017-08-31
申请号：US15510150
申请日：2015-09-09
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Andrew Quoc Viet , Nicholas R. Wurtz
IPC: C07D249/16 , C07D471/04 , C07D487/04 , A61K31/437 , A61K31/7064
CPC classification number: C07D249/16 , A61K31/437 , A61K31/7064 , C07D471/04 , C07D487/04
Abstract: The present invention provides compounds of Formula (I): wherein A, X and Y are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are myeloperoxidase (MPO) inhibitors and/or eosinophil peroxidase (EPX) inhibitors, which may be used as medicaments.
-
-
-
-
-
-
-
Search Results
8
records
(took 0.027 seconds)
