公开(公告)号：US20230182127A1

公开(公告)日：2023-06-15

申请号：US18076667

申请日：2022-12-07

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Vishal Sharma ,  Ronald Lebofsky ,  Man Cheng ,  Adam McCoy ,  Kalyan Handique ,  Eric Pomaranski

IPC: B01L3/00 ,  C12N13/00

CPC classification number: B01L3/502 ,  C12N13/00 ,  B01L2200/026 ,  B01L2200/0668 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/047 ,  B01L2300/0893

Abstract: Inventions covered include methods, systems, and compositions for sample processing, involving morphology-adjustable (e.g., tunable on-demand) functionalized particles. In some embodiments, a method can include distributing a set of functionalized particles, in a first morphological state, across a set of partitions; transitioning the set of functionalized particles, at the set of partitions, from the first morphological state to a second morphological state; transitioning the set of functionalized particles, at the set of partitions, from the second morphological state to a third morphological state, and inducing interactions between the set of functionalized particles and a set of targets, within the set of partitions and according to a set of operations with a set of process fluids.