公开(公告)号：US20170159132A1

公开(公告)日：2017-06-08

申请号：US15411855

申请日：2017-01-20

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Steven T. OKINO ,  Yan WANG

IPC: C12Q1/68

Abstract: This invention provides methods of determining the biological, pathological, genetic, epigenetic or disease status in a biological sample by determining the methylation status of a subpopulation of genomic DNA in the sample.

公开(公告)号：US20160273027A1

公开(公告)日：2016-09-22

申请号：US15034548

申请日：2014-11-21

Applicant: BIO-RAD LABORATORIES, INC.

Inventor： Steven T. OKINO ,  Man CHENG

IPC: C12Q1/68

CPC classification number: C12Q1/6813 ,  C12Q1/683 ,  C12Q2537/16 ,  C12Q2563/159

Abstract: The present invention provides methods for determining whether two or more nucleic acid molecules or two or more regions of a nucleic acid molecule in a sample are in close proximity to each other due to direct or indirect physical interactions.

Abstract translation: 本发明提供了用于确定样品中核酸分子的两个或多个核苷酸分子或两个或更多个区域是否由于直接或间接物理相互作用而彼此靠近的方法。