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公开(公告)号：US20200183025A1
公开(公告)日：2020-06-11
申请号：US16212326
申请日：2018-12-06
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Yi Qiang , Xiaoli Li , Kent C. Burr
Abstract: A method and apparatus are provided for positron emission imaging to calibrate timing of a pixelated gamma detector using multi-channel events. The apparatus can include processing circuitry configured to obtain calibration data representing a time and a position at which gamma rays are detected at a plurality of detector elements, and determine which gamma-ray detections of the calibration data correspond to multi-channel detections in which energy of a respective gamma ray is shared and detected by two or more of the plurality of detector elements. Additionally, the processing circuitry can be configured to determine a timing calibration of the plurality of detector elements by optimizing an objective representing agreement between time data of the multi-channel detections in the calibration data and the timing calibration.
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公开(公告)号：US11835668B2
公开(公告)日：2023-12-05
申请号：US17345823
申请日：2021-06-11
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Yi Qiang , Kent C. Burr , Peng Peng , Xiaoli Li
CPC classification number: G01T1/2985 , A61B6/037 , A61B6/5258
Abstract: A circuit for receiving signals from a photodetector array arranged to detect signals generated by a crystal includes a plurality of summing circuits having weighting circuits, the summing circuits being configured to produce outputs corresponding to a total energy of the signals, a position of the signals in a first dimension of the photodetector array, a position of the signals in a second dimension of the photodetector array, and a radius of a charge distribution of the signals.
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公开(公告)号：US11663735B2
公开(公告)日：2023-05-30
申请号：US17015670
申请日：2020-09-09
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Karthikayan Balakrishnan , Kent C. Burr
CPC classification number: G06T7/70 , A61B6/0407 , A61B6/0492 , G06T7/0012 , A61B6/032 , A61B6/037 , A61B2090/3937 , A61B2090/3979 , G06T2207/10048 , G06T2207/30004 , G06T2207/30204
Abstract: Optical sensors and optical markers are placed on components in a medical system to provide calibration and alignment, such as on a patient transportation mechanism and spatially separated medical diagnostic devices. Image processing circuitry uses the data captured by these optical devices to coordinate their movements and/or position. This enables scans that were captured in multiple medical diagnostic devices to be accurately aligned.
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公开(公告)号：US11543545B2
公开(公告)日：2023-01-03
申请号：US16788741
申请日：2020-02-12
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Xiaoli Li , Yi Qiang , Kent C. Burr
Abstract: A method and apparatus are provided for nonlinear energy correction of a gamma-ray detector using a calibration spectrum acquired from the background radiation of lutetium isotope 176 (Lu-176) present in scintillators in the gamma-ray detector. Further, by periodically acquiring Lu-176 spectra using the background radiation from the scintillators, the nonlinear energy correction can be monitored to detect when changes in the gamma-ray detector cause the detector to go out of calibration, and then use a newly acquired Lu-176 spectrum to update the calibration of the nonlinear energy correction as needed. The detector calibration is performed by comparing a reference histogram to a calibration histogram generated using the nonlinear energy correction, and adjusting the parameters of the nonlinear energy correction until the two histograms match. Alternatively, the detector calibration is performed by comparing reference and calibration values for specific spectral features, rather than for the whole Lu-176 spectrum.
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公开(公告)号：US11255985B2
公开(公告)日：2022-02-22
申请号：US16738828
申请日：2020-01-09
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Kent C. Burr , Xiaoli Li
Abstract: A method and apparatus are provided for positron emission imaging to calibrate energy measurements of a pixilated gamma-ray detector using energy calibration based on a calibration with a distribution energy signature (i.e., having more spectral features than just a single full-energy peak). The energy calibration can be performed using a deep learning (DL) network or a physics-based model. Using the DL network, a calibration spectrum is applied to either generate the measured-signal values of known energy values (e.g., spectral peaks for spectra of various radioactive isotopes) or the parameters of an energy-calibration function/model.
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Patent Agency Ranking
公开(公告)号：US12042326B2
公开(公告)日：2024-07-23
申请号：US17168852
申请日：2021-02-05
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Kent C. Burr , Yi Qiang , Xiaoli Li
CPC classification number: A61B6/58 , A61B6/037 , A61B6/4275 , G01T1/2985
Abstract: In a gamma-ray detector system, such as a PET detector, coincidence events between multiple detector elements can be caused by inter-detector scattering and/or energy escape of the multi-stage radiation background in the scintillator crystals. Because these types of coincidence events are more likely to happen between nearby elements, they can be measured, analyzed and ultimately used to identify arrangement errors of detector elements in a gamma-ray detector system.
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公开(公告)号：US11573339B2
公开(公告)日：2023-02-07
申请号：US16907972
申请日：2020-06-22
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Xiaoli Li , Yi Qiang , Kent C. Burr , Peng Peng
Abstract: A method and system for providing improved timing calibration information for use with apparatuses performing Time of Flight Positron Emission Tomography scans. Relative timing offset, including timing walk, within a set of processing units in the scanner are obtained and corrected using a stationary limited extent positron-emitting source, and timing offset between the set of processing units is calibrated using an internal radiation source, for performing calibration.
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公开(公告)号：US10962662B2
公开(公告)日：2021-03-30
申请号：US16212326
申请日：2018-12-06
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Yi Qiang , Xiaoli Li , Kent C. Burr
Abstract: A method and apparatus are provided for positron emission imaging to calibrate timing of a pixelated gamma detector using multi-channel events. The apparatus can include processing circuitry configured to obtain calibration data representing a time and a position at which gamma rays are detected at a plurality of detector elements, and determine which gamma-ray detections of the calibration data correspond to multi-channel detections in which energy of a respective gamma ray is shared and detected by two or more of the plurality of detector elements. Additionally, the processing circuitry can be configured to determine a timing calibration of the plurality of detector elements by optimizing an objective representing agreement between time data of the multi-channel detections in the calibration data and the timing calibration.
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公开(公告)号：US10768318B2
公开(公告)日：2020-09-08
申请号：US16163319
申请日：2018-10-17
Applicant: Canon Medical Systems Corporation
Inventor： Yi Qiang , Huini Du , Kent C. Burr
Abstract: A method and apparatus are provided for positron emission imaging to correct a recorded energy of a detected gamma ray, when the gamma ray is scattered during detection. When scattering occurs, the energy of a single gamma ray can be distributed across multiple detector elements—a multi-channel detection. Nonlinearities in the detection process and charge/light sharing among adjacent channels can result in the summed energies from the multiple crystals of a multi-channel detection deviating from the energy that would be measured in single-channel detection absent scattering. This deviation is corrected by applying one or more correction factors (e.g., multiplicative or additive) that shifts the summed energies of multi-channel detections to agree with a known predefined energy (e.g., 511 keV). The correction factors can be stored in a look-up-table that is segmented to accommodate variations in the multi-channel energy shift based on the level of energy sharing.
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公开(公告)号：US12007513B2
公开(公告)日：2024-06-11
申请号：US17581005
申请日：2022-01-21
Applicant: CANON MEDICAL SYSTEMS CORPORATION
Inventor： Peng Peng , Yi Qiang , Xiaoli Li , Kent C. Burr , Manabu Teshigawara
CPC classification number: G01T1/1642 , A61B6/037 , A61B6/4258 , G01T1/1644 , G01T1/2018 , G01T1/2985
Abstract: A method and apparatuses for a radiation detector apparatus, comprising a scintillator array comprising a plurality of scintillator crystals. The plurality of scintillator crystals includes a first scintillator crystal and a second scintillator crystal adjacent to the first scintillator crystal within the scintillator array. A photosensor array comprising a plurality of photosensors including a first photosensor configured to detect photons from the first scintillator crystal. A first separator positioned between the first scintillator crystal and the second scintillator crystal. First separator optically separates the first scintillator crystal and the second scintillator crystal such that the first photosensor detects photons from the first scintillator crystal and not from the second scintillator crystal.
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