公开(公告)号：US20210178636A1

公开(公告)日：2021-06-17

申请号：US17170706

申请日：2021-02-08

Applicant: CARNEGIE MELLON UNIVERSITY

Inventor： Philip R. LeDuc ,  O. Burak Ozdoganlar ,  Mary E. Wilson ,  Emrullah Korkmaz ,  Yadong Wang ,  Donna Beer-Stolz

IPC: B29B11/14 ,  B29C33/38

Abstract: The present invention relates generally to a method that is used to create three-dimensional synthetic vascular networks. Micromachining and molding techniques are used to create a template in a shape that mimics a biological network. Cellular material can be seeded around the template or a space created by the template and grown into an engineered tissue-construct.

公开(公告)号：US10919183B2

公开(公告)日：2021-02-16

申请号：US14750620

申请日：2015-06-25

Applicant: CARNEGIE MELLON UNIVERSITY, a Pennsylvania Non-Profit Corporation

Inventor： Philip R. LeDuc ,  O. Burak Ozdoganlar ,  Mary E. Wilson ,  Emrullah Korkmaz ,  Yadong Wang ,  Donna Beer-Stolz

IPC: C12N11/04 ,  B29B11/14 ,  B29C33/38 ,  B29L31/00 ,  B29L23/00

Abstract: The present invention relates generally to a method that is used to create three-dimensional synthetic vascular networks. Micromachining and molding techniques are used to create a template in a shape that mimics a biological network. Cellular material can be seeded around the template or a space created by the template and grown into an engineered tissue-construct.

公开(公告)号：US20150376595A1

公开(公告)日：2015-12-31

申请号：US14750620

申请日：2015-06-25

Applicant: CARNEGIE MELLON UNIVERSITY, a Pennsylvania Non-Profit Corporation

Inventor： Philip R. LeDuc ,  O. Burak Ozdoganlar ,  Mary E. Wilson ,  Emrullah Korkmaz ,  Yadong Wang ,  Donna Beer-Stolz

IPC: C12N11/04 ,  B29B11/14

CPC classification number: B29B11/14 ,  B29C33/3842 ,  B29L2023/00 ,  B29L2031/7534 ,  B29L2031/756

Abstract: The present invention relates generally to a method that is used to create three-dimensional synthetic vascular networks. Micromachining and molding techniques are used to create a template in a shape that mimics a biological network. Cellular material can be seeded around the template or a space created by the template and grown into an engineered tissue-construct.

Abstract translation: 本发明一般涉及一种用于产生三维合成血管网络的方法。 微加工和成型技术用于创建模仿生物网络的形状的模板。 细胞材料可以在模板周围或由模板产生的空间中种植并生长成工程化的组织构建体。