公开(公告)号：US20230159531A1

公开(公告)日：2023-05-25

申请号：US17988340

申请日：2022-11-16

Applicant: CHDI Foundation, Inc.

Inventor： Longbin Liu ,  Celia Dominguez ,  Nikolay V. Plotnikov ,  Alan Haughan ,  Andrew Stott ,  Brett Cosgrove ,  Cole Clissold ,  Huw Vater ,  Jonathan Spencer ,  William Esmieu ,  Karine Malagu ,  Mark Chambers

IPC: C07D471/10 ,  C07D413/14 ,  C07D405/14 ,  C07D403/14 ,  C07D471/04 ,  A61K45/06

CPC classification number: C07D471/10 ,  C07D413/14 ,  C07D405/14 ,  C07D403/14 ,  C07D471/04 ,  A61K45/06

Abstract: Provided herein are certain compounds useful as HTT modulators. Such compound are useful in the treatment of Huntington's disease.

公开(公告)号：US12281116B2

公开(公告)日：2025-04-22

申请号：US17988340

申请日：2022-11-16

Applicant: CHDI Foundation, Inc.

Inventor： Longbin Liu ,  Celia Dominguez ,  Nikolay V. Plotnikov ,  Alan Haughan ,  Andrew Stott ,  Brett Cosgrove ,  Cole Clissold ,  Huw Vater ,  Jonathan Spencer ,  William Esmieu ,  Karine Malagu ,  Mark Chambers

IPC: C07D471/10 ,  A61K45/06 ,  C07D403/14 ,  C07D405/14 ,  C07D413/14 ,  C07D471/04

Abstract: Provided herein are certain compounds useful as HTT modulators. Such compound are useful in the treatment of Huntington's disease.