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公开(公告)号:US20220024849A1
公开(公告)日:2022-01-27
申请号:US16938238
申请日:2020-07-24
Applicant: CHIROGATE INTERNATIONAL INC.
Inventor: SHIH-YI WEI , MING-KUN HSU , TZYH-MANN WEI
IPC: C07C201/02
Abstract: Processes for preparing latanoprostene bunod and an intermediate prepared from the process. Also latanoprostene bunod compositions having high-purity latanoprostene bunod.
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公开(公告)号:US20210188757A1
公开(公告)日:2021-06-24
申请号:US16720711
申请日:2019-12-19
Applicant: CHIROGATE INTERNATIONAL INC.
Inventor: SHIH-YI WEI , JIAN-BANG JHENG , MING-KUN HSU , MIN-KUAN HSU , TZYH-MANN WEI
Abstract: There is provided a crystalline Form I of anhydrous Treprostinil and processes for the preparation thereof. The crystalline Form I of anhydrous Treprostnil is a stable crystalline form, which can provide steady physicochemical properties for pharmaceutical formulations, and is advantageous widely and safety used in storage, shipment, and handling for commercially considerations.
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