CELL CULTURE SUBSTRATE HAVING UNIFORM SURFACE COATING
    3.
    发明申请
    CELL CULTURE SUBSTRATE HAVING UNIFORM SURFACE COATING 审中-公开
    具有均匀表面涂层的细胞培养基底

    公开(公告)号:US20140141503A1

    公开(公告)日:2014-05-22

    申请号:US13892697

    申请日:2013-05-13

    CPC classification number: C12M23/34 C12M23/10 C12M23/20

    Abstract: An article for culturing cells includes (i) a substrate having a surface; (ii) a plurality of pillars extending from the surface of the substrate; and (iii) a polymeric coating disposed on the surface of the substrate between the pillars, forming a plurality of mini-menisci on the surface of the substrate between the plurality of pillars. The mini-menisci may have diameters of from about 20 to about 250 micrometers. The plurality of pillars are spaced apart from one another in a manner to encourage cell growth on the mini-menisci rather than the on top of the pillars. Such articles may effectively address issues associated with the meniscus effect on a global scale.

    Abstract translation: 用于培养细胞的制品包括(i)具有表面的基材; (ii)从所述基板的表面延伸的多个支柱; 和(iii)在所述支柱之间设置在所述基板的表面上的聚合物涂层,在所述多个支柱之间的所述基板的表面上形成多个微型半月板。 微型半月板可以具有约20至约250微米的直径。 多个支柱以鼓励小型半月板而不是在柱顶上的细胞生长的方式彼此间隔开。 这样的文章可以在全球范围内有效地解决与半月板效应相关的问题。

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