公开(公告)号：US20230168178A1

公开(公告)日：2023-06-01

申请号：US17994395

申请日：2022-11-28

Applicant: CYTEK BIOSCIENCES, INC.

Inventor： Qing Shao ,  Ming Yan

IPC: G01N15/14

CPC classification number: G01N15/1434 ,  G01N15/1404 ,  G01N2015/1006

Abstract: An optical fiber forward scatter channel in a flow cytometer is disclosed. A detector system in the flow cytometer includes fiber optic cable for receiving scattered light from an incident laser light that is directed at cells/particles passing through the flow cytometer. The fiber optic cable delivers the scattered light to a sensor system, which collects data to perform analyses on the scattered light. Such analyses may include, for example, calculating the size of a cell/particle, counting cells/particles, and so on. The fiber optic cable is an inherently efficient and accurate filter for the acceptance or rejection of the scattered light.

公开(公告)号：US12209948B2

公开(公告)日：2025-01-28

申请号：US17304843

申请日：2021-06-26

Applicant: CYTEK BIOSCIENCES, INC.

Inventor： Maria Jaimes ,  Zhenyu Zhang ,  Jian Zhou ,  Huimin Gu ,  Qing Shao ,  Ming Yan ,  David Vrane

IPC: G01N15/14 ,  G01N15/00 ,  G01N15/1434 ,  G01N15/01

Abstract: In one embodiment, a method of building an optimized color flow cytometry panel is disclosed using a full spectrum flow cytometer with five excitation lasers and five corresponding detection modules. In another embodiment, a graphical user interface is disclosed generated by a server computer from a fluorochrome database and displayed by a client computer to assist in the selection of a set of fluorochromes for use in an assay to analyze biological samples. The GUI can display spectra graphs to visually show how fluorochromes may overlap and can generate similarity indexes for the paired fluorochrome interference and a complexity index for overall many to many interferences generated by a selected group or set of fluorochromes.