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公开(公告)号：US20100292185A1
公开(公告)日：2010-11-18
申请号：US12776745
申请日：2010-05-10
申请人： Christopher J. Burns , Rajesh Goswami , Randy W. Jackson , Thomas Lessen , Weiping Li , Daniel Pevear , Pavan Kumar Tirunahari , Hongyu Xu
发明人： Christopher J. Burns , Rajesh Goswami , Randy W. Jackson , Thomas Lessen , Weiping Li , Daniel Pevear , Pavan Kumar Tirunahari , Hongyu Xu
CPC分类号： A61K45/06 , A61K31/69 , C07F5/025 , A61K2300/00
摘要： Disclosed herein are α-aminoboronic acids and their derivatives which act as inhibitors of beta-lactamases. Also disclosed herein are pharmaceutical compositions comprising α-aminoboronic acids and methods of use thereof.
摘要翻译： 本文公开了作为β-内酰胺酶抑制剂的α-氨基硼酸及其衍生物。 本文还公开了包含α-氨基硼酸的药物组合物及其使用方法。
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公开(公告)号：US20100286092A1
公开(公告)日：2010-11-11
申请号：US12742526
申请日：2008-11-13
IPC分类号： A61K31/69 , C07F5/02 , C07D333/02 , A61P31/04
CPC分类号： C07F5/025
摘要： Disclosed herein are α-aminoboronic acids and their derivatives which act as inhibitors of beta-lactamases. Also disclosed herein are pharmaceutical compositions comprising α-aminoboronic acids and methods of use thereof.
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公开(公告)号：US20100120715A1
公开(公告)日：2010-05-13
申请号：US12464609
申请日：2009-05-12
CPC分类号： C07F5/025
摘要： Disclosed herein are α-aminoboronic acids and their derivatives which act as inhibitors of beta-lactamases. Also disclosed herein are pharmaceutical compositions comprising α-aminoboronic acids and methods of use thereof.
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