公开(公告)号：US20100292185A1

公开(公告)日：2010-11-18

申请号：US12776745

申请日：2010-05-10

Applicant: Christopher J. Burns ,  Rajesh Goswami ,  Randy W. Jackson ,  Thomas Lessen ,  Weiping Li ,  Daniel Pevear ,  Pavan Kumar Tirunahari ,  Hongyu Xu

Inventor： Christopher J. Burns ,  Rajesh Goswami ,  Randy W. Jackson ,  Thomas Lessen ,  Weiping Li ,  Daniel Pevear ,  Pavan Kumar Tirunahari ,  Hongyu Xu

IPC: A61K31/69 ,  C07F5/02 ,  A61P31/00

CPC classification number: A61K45/06 ,  A61K31/69 ,  C07F5/025 ,  A61K2300/00

Abstract: Disclosed herein are α-aminoboronic acids and their derivatives which act as inhibitors of beta-lactamases. Also disclosed herein are pharmaceutical compositions comprising α-aminoboronic acids and methods of use thereof.

Abstract translation: 本文公开了作为β-内酰胺酶抑制剂的α-氨基硼酸及其衍生物。 本文还公开了包含α-氨基硼酸的药物组合物及其使用方法。

公开(公告)号：US20100286092A1

公开(公告)日：2010-11-11

申请号：US12742526

申请日：2008-11-13

Applicant: Christopher J. Burns ,  Randy W. Jackson ,  Rajesh Goswami ,  Hongyu Xu

Inventor： Christopher J. Burns ,  Randy W. Jackson ,  Rajesh Goswami ,  Hongyu Xu

IPC: A61K31/69 ,  C07F5/02 ,  C07D333/02 ,  A61P31/04

CPC classification number: C07F5/025

Abstract: Disclosed herein are α-aminoboronic acids and their derivatives which act as inhibitors of beta-lactamases. Also disclosed herein are pharmaceutical compositions comprising α-aminoboronic acids and methods of use thereof.

公开(公告)号：US20100120715A1

公开(公告)日：2010-05-13

申请号：US12464609

申请日：2009-05-12

Applicant: Christopher J. Burns ,  Randy W. Jackson ,  Rajesh Goswami ,  Hongyu Xu

Inventor： Christopher J. Burns ,  Randy W. Jackson ,  Rajesh Goswami ,  Hongyu Xu

IPC: A61K31/69 ,  C07F5/02 ,  A61P31/04

CPC classification number: C07F5/025

Abstract: Disclosed herein are α-aminoboronic acids and their derivatives which act as inhibitors of beta-lactamases. Also disclosed herein are pharmaceutical compositions comprising α-aminoboronic acids and methods of use thereof.