公开(公告)号：US20130152309A1

公开(公告)日：2013-06-20

申请号：US13767713

申请日：2013-02-14

Applicant: ConvaTec Technologies Inc.

Inventor： Roger BRAY

IPC: A61L15/46

CPC classification number: A61L15/28 ,  A61L15/18 ,  A61L15/44 ,  A61L15/46 ,  A61L2300/104 ,  A61L2300/404 ,  C08L5/04 ,  C08L1/28

Abstract: An antibacterial wound dressing is based on or derived from gel-forming fibres such as carboxymethyl cellulose or alginate fibres having silver ions linked thereto at some but not all of the exchangeable sites such that the distribution of silver ions over the exchangeable sites is substantially uniform. The silvered fibres for the wound dressing can be prepared by contacting an assembly of precursor gel-forming fibres having exchangeable sites under conditions which do not cause irreversible gelling of the fibres with an amount of a solution containing silver ions so as to link silver ions at some but not all of the exchangeable sites, the whole of the assembly of precursor gel-forming fibres being contacted essentially simultaneously with the entire solution containing silver ions.

Abstract translation: 抗菌伤口敷料基于或衍生自凝胶形成纤维，例如羧甲基纤维素或在一些但不是全部可交换位点处具有银离子的藻酸盐纤维，使得银离子在可交换位点上的分布基本上是均匀的。 用于伤口敷料的镀银纤维可以通过使具有可交换位置的前体凝胶形成纤维的组件在不引起纤维不可逆胶凝的条件下与一定量的含银离子的溶液接触来制备，以便将银离子连接在 一些但不是全部的可交换位点，前体凝胶形成纤维的整体组装基本上与含有银离子的整个溶液同时接触。