公开(公告)号：US20170100426A1

公开(公告)日：2017-04-13

申请号：US15128682

申请日：2015-03-20

Applicant: DAICEL CORPORATION

Inventor： Shu SHIMAMOTO ,  Toshikazu NAKAMURA ,  Shizuka UKITA ,  Tsuyoshi NAKAMURA ,  Ryoko YAMAUCHI ,  Hiroshi KOBAYASHI ,  Tatsuya MORITA ,  Tomomi GENDA

IPC: A61K31/717

CPC classification number: A61K31/717 ,  A23L33/24

Abstract: A nutrient composition, a lipid metabolism-improving agent, and prophylactic and/or therapeutic agents typically for inflammatory bowel diseases, immune disorders, cancers, non-alcoholic steatohepatitis, obesity, diabetes, and hypercholesterolemia each contain a cellulose acetate having a total degree of acetyl substitution of 0.4 to 1.1. The cellulose acetate may be one having a compositional distribution index (CDI) of 2.0 or less, where the CDI is defined by the formula: CDI=(Measured value of half height width of chemical composition)/(Theoretical value of half height width of chemical composition) where the measured value of half height width of chemical composition represents a half height width of chemical composition determined by HPLC analysis of a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample), and the theoretical value of half height width of chemical composition=2.35482√{square root over (3*DPw*(DS/3)*(1−DS/3))}/DPw  [Math. 1] where DS is the total degree of acetyl substitution; and DPw is a weight-average degree of polymerization determined by a GPC-light scattering method using a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample).