公开(公告)号：US20170088636A1

公开(公告)日：2017-03-30

申请号：US15126893

申请日：2014-03-19

Applicant: DAICEL CORPORATION

Inventor： Tomohiro HASHIZUME ,  Shizuka UKITA ,  Shu SHIMAMOTO ,  Toshikazu NAKAMURA

IPC: C08B3/16

CPC classification number: C08B3/16

Abstract: Provided is a novel cellulose derivative having excellent water resistance. This is a cellulose acylate oxoalkanoate which is a cellulose derivative corresponding to cellulose, except with substituents replacing part or all of hydrogen atoms in the hydroxy groups of the cellulose. The substituents includes a group represented by General Formula (1) and a group represented by General Formula (2). The cellulose acylate oxoalkanoate has a degree x of substitution with the group represented by General Formula (1), a degree y of substitution with the group represented by General Formula (2), and a degree z of unsubstitution, where x, y, and z meet conditions specified by Expressions (A), (B), and (C): 0.1≦x≦2.99  (A) 0.01≦y≦2.90  (B) z=3−x−y  (C)

公开(公告)号：US20220227891A1

公开(公告)日：2022-07-21

申请号：US17612651

申请日：2020-06-24

Applicant: DAICEL CORPORATION

Inventor： Shuuji YOSHIOKA ,  Toshikazu NAKAMURA ,  Shu SHIMAMOTO ,  Takao KISHIMOTO

IPC: C08B3/06 ,  C08B3/28 ,  C08B3/24 ,  A61K31/717 ,  A61P3/04 ,  A61P3/06

Abstract: The present invention is to provide a cellulose acetate that has a low total degree of acetyl substitution and a degree of acetyl substitution at 6-position that is lower compared to the degrees of acetyl substitution at 2-position and 3-position of a glucose ring, and has excellent water solubility. A cellulose acetate having: a total degree of acetyl substitution of 0.4 or greater and 0.9 or less, a proportion of a degree of acetyl substitution at 6-position in the total degree of acetyl substitution of 0% or greater and 18% or less, and a light transmittance at 660 nm of 5% or greater in 4 wt. % aqueous solution.

公开(公告)号：US20210221918A1

公开(公告)日：2021-07-22

申请号：US17056468

申请日：2019-06-12

Applicant: NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY ,  NIPPON PAPER INDUSTRIES CO., LTD. ,  DAICEL CORPORATION

Inventor： Yasumitsu URAKI ,  Haruo KONNO ,  Shu SHIMAMOTO

IPC: C08B3/06 ,  C08B1/00 ,  C08L1/12 ,  C08L57/00 ,  C08L87/00

Abstract: An object of the present invention is to provide cellulose acetate that has excellent compatibility with a resin, can reinforce a resin, and has excellent thermal stability. An embodiment of the present invention is cellulose acetate having a cellulose triacetate I crystal structure, wherein a temperature at which a weight loss relative to weight at 100° C. reaches 5% is 200° C. or higher when the cellulose acetate is heated at a heating rate of 10° C./min under a nitrogen atmosphere.

公开(公告)号：US20210379097A1

公开(公告)日：2021-12-09

申请号：US17284927

申请日：2019-10-24

Applicant: DAICEL CORPORATION

Inventor： Hiroshi OHNO ,  Tadashi TAKEUCHI ,  Shu SHIMAMOTO ,  Shuuji YOSHIOKA ,  Eiji MIYAUCHI ,  Hiroki NEGISHI

IPC: A61K31/717 ,  A23L33/10

Abstract: An object is to provide a Th1-increasing agent that can reduce constraints on storage conditions and feeding form and sufficiently increase Th1 at lower doses. A Th1-increasing agent containing a cellulose derivative as an active ingredient, the cellulose derivative having a degree of butyryl substitution of 0.3 or greater and 2.6 or less, and a total degree of substitution of 0.5 or greater and 2.8 or less.

公开(公告)号：US20170100426A1

公开(公告)日：2017-04-13

申请号：US15128682

申请日：2015-03-20

Applicant: DAICEL CORPORATION

Inventor： Shu SHIMAMOTO ,  Toshikazu NAKAMURA ,  Shizuka UKITA ,  Tsuyoshi NAKAMURA ,  Ryoko YAMAUCHI ,  Hiroshi KOBAYASHI ,  Tatsuya MORITA ,  Tomomi GENDA

IPC: A61K31/717

CPC classification number: A61K31/717 ,  A23L33/24

Abstract: A nutrient composition, a lipid metabolism-improving agent, and prophylactic and/or therapeutic agents typically for inflammatory bowel diseases, immune disorders, cancers, non-alcoholic steatohepatitis, obesity, diabetes, and hypercholesterolemia each contain a cellulose acetate having a total degree of acetyl substitution of 0.4 to 1.1. The cellulose acetate may be one having a compositional distribution index (CDI) of 2.0 or less, where the CDI is defined by the formula: CDI=(Measured value of half height width of chemical composition)/(Theoretical value of half height width of chemical composition) where the measured value of half height width of chemical composition represents a half height width of chemical composition determined by HPLC analysis of a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample), and the theoretical value of half height width of chemical composition=2.35482√{square root over (3*DPw*(DS/3)*(1−DS/3))}/DPw  [Math. 1] where DS is the total degree of acetyl substitution; and DPw is a weight-average degree of polymerization determined by a GPC-light scattering method using a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample).

公开(公告)号：US20160032020A1

公开(公告)日：2016-02-04

申请号：US14775369

申请日：2014-03-12

Applicant: DAICEL CORPORATION

Inventor： Shizuka UKITA ,  Hiroki TANIGUCHI ,  Shu SHIMAMOTO ,  Toshikazu NAKAMURA

IPC: C08B3/06 ,  C08B3/24

CPC classification number: C08B3/06 ,  C08B3/24 ,  C08B3/28 ,  C08J5/18 ,  C08J2301/12 ,  C08L1/12 ,  C08L1/14 ,  D01F2/28

Abstract: A cellulose acetate according to the present invention has a total degree of acetyl substitution of 0.4 to 1.1 and has a compositional distribution index (CDI) of 3.0 or less, where the CDI is specified by the formula: CDI=(Measured value of half height width of chemical composition)/(Theoretical value of half height width of chemical composition) where the measured value of half height width of chemical composition is a half height width of chemical composition determined by analyzing a cellulose acetate propionate by HPLC, where the cellulose acetate propionate is prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample); and Theoretical value of half height width of chemical composition=2·35482√{square root over (3*DPw*(DS/3)*(1−DS/3))}{square root over (3*DPw*(DS/3)*(1−DS/3))}/DPw  [Math. 1] where DS is the total degree of acetyl substitution; and DPw is a weight-average degree of polymerization determined by a GPC-light scattering method using a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample).

Abstract translation: 本发明的乙酸纤维素的总乙酰基取代度为0.4〜1.1，组成分布指数（CDI）为3.0以下，其中CDI由下式确定：CDI =（半高度的测定值 化学成分的宽度）/化学成分的半高宽度的测定值为通过HPLC分析醋酸丙酸纤维素而测定的化学成分的半高宽度的化学成分的半高宽度的理论值，其中乙酸纤维素 通过丙酰化乙酸纤维素（样品）的所有残留羟基来制备丙酸酯; （3 * DPw *（DS / 3）*（1-DS / 3））} {平方根超过（3 * DPw *（DS））的化学成分的半高宽度的理论值= 2·35482 / 3）*（1-DS / 3））} / DPw [ 1]其中DS是乙酰基取代的总量; DPw是通过使用通过丙酰化乙酸纤维素（样品）的所有残留羟基制备的丙酸纤维素的GPC-光散射法测定的重均聚合度。

公开(公告)号：US20200288762A1

公开(公告)日：2020-09-17

申请号：US16759074

申请日：2018-10-23

Applicant: DAICEL CORPORATION

Inventor： Tadashi TAKEUCHI ,  Eiji MIYAUCHI ,  Shu SHIMAMOTO ,  Akinobu MATSUYAMA ,  Hiroshi OHNO

IPC: A23L33/24 ,  A61K31/717 ,  G06F17/18

Abstract: Object of the present invention is to provide an intestinal immune-enhancing agent that can sufficiently increase IgA in the intestinal tract with a low dose while maintaining an increased amount of IgA for an extended period of time. Provided is an intestinal immune-enhancing agent containing a cellulose acetate that has a total degree of acetyl substitution from 0.4 to 1.1.

公开(公告)号：US20190151349A1

公开(公告)日：2019-05-23

申请号：US16258224

申请日：2019-01-25

Applicant: DAICEL CORPORATION

Inventor： Shu SHIMAMOTO ,  Toshikazu NAKAMURA ,  Shizuka UKITA ,  Tsuyoshi NAKAMURA ,  Ryoko YAMAUCHI ,  Hiroshi KOBAYASHI

IPC: A61K31/717 ,  A23L33/24 ,  A23K50/40 ,  A61K45/06 ,  A23K20/163 ,  A23K50/30 ,  A23K50/75 ,  A23K50/10

Abstract: A nutrient composition contains a cellulose acetate having a total degree of acetyl substitution of 0.4 to 1.1. The cellulose acetate may have a compositional distribution index (CDI) of 2.0 or less, where the CDI is specified by the formula: CDI=(Measured value of half height width of chemical composition)/(Theoretical value of half height width of chemical composition) where the measured value of half height width of chemical composition represents the half height width of chemical composition determined by HPLC analysis of a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample); and [Math. 1] the theoretical value of half height width of chemical composition =2. 35482√{square root over (3*DPw*(DS/3)*(1−DS/3))}/DPw where DS is the total degree of acetyl substitution; and DPw is a weight-average degree of polymerization determined by a GPC-light scattering method using a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample).

公开(公告)号：US20160333500A1

公开(公告)日：2016-11-17

申请号：US15111688

申请日：2014-01-15

Applicant: DAICEL CORPORATION

Inventor： Shu SHIMAMOTO ,  Shizuka OKADA ,  Hiroki TANIGUCHI ,  Toshikazu NAKAMURA

IPC: D01F2/28 ,  D04H1/425 ,  D04H1/728 ,  D01D5/00

CPC classification number: D01F2/28 ,  D01D5/003 ,  D04H1/425 ,  D04H1/728 ,  D10B2201/28 ,  D10B2401/024 ,  D10B2401/12

Abstract: Provided are a cellulose acetate fiber and a cellulose acetate fiber molded article which are excellent in water solubility and biodegradability and are small in load onto the natural environment even when allowed to stand still in the environment. The invention provides a cellulose acetate fiber containing cellulose acetate having a total degree of acetyl substitution of 0.4 to 1.3 and a compositional distribution index (CDI) of 2.0 or less as well as a cellulose acetate fiber molded article.

Abstract translation: 本发明提供水溶性和生物降解性优异的乙酸纤维素纤维素和醋酸纤维素纤维成型体，即使在环境中静止的情况下也能够在自然环境中负载小。 本发明提供一种醋酸纤维素，其醋酸纤维素的总乙酰基取代度为0.4〜1.3，组成分布指数（CDI）为2.0以下，以及醋酸纤维素纤维成型体。

公开(公告)号：US20160317568A1

公开(公告)日：2016-11-03

申请号：US15106095

申请日：2014-03-24

Applicant: DAICEL CORPORATION

Inventor： Shu SHIMAMOTO ,  Toshikazu NAKAMURA ,  Shizuka UKITA ,  Tsuyoshi NAKAMURA ,  Ryoko YAMAUCHI ,  Hiroshi KOBAYASHI

IPC: A61K31/717 ,  A23L33/24 ,  A23K50/40 ,  A23K20/163 ,  A23K50/75

CPC classification number: A61K31/717 ,  A23K20/163 ,  A23K50/10 ,  A23K50/30 ,  A23K50/40 ,  A23K50/75 ,  A23L33/24 ,  A23V2002/00 ,  A61K45/06 ,  A61K2300/00

Abstract: A nutrient composition contains a cellulose acetate having a total degree of acetyl substitution of 0.4 to 1.1. The cellulose acetate may have a compositional distribution index (CDI) of 2.0 or less, where the CDI is specified by the formula: CDI=(Measured value of half height width of chemical composition)/(Theoretical value of half height width of chemical composition) where the measured value of half height width of chemical composition represents the half height width of chemical composition determined by HPLC analysis of a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample); and the theoretical value of half height width of chemical composition=2.35482√{square root over (3*DPw*(DS/3)*(1−DS/3))}/DPw  [Math. 1] where DS is the total degree of acetyl substitution; and DPw is a weight-average degree of polymerization determined by a GPC-light scattering method using a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample).

Abstract translation: 其中DS是乙酰基取代的总量; DPw是通过使用通过丙酰化乙酸纤维素（样品）的所有残留羟基制备的丙酸纤维素的GPC-光散射法测定的重均聚合度。