公开(公告)号：US20170100426A1

公开(公告)日：2017-04-13

申请号：US15128682

申请日：2015-03-20

Applicant: DAICEL CORPORATION

Inventor： Shu SHIMAMOTO ,  Toshikazu NAKAMURA ,  Shizuka UKITA ,  Tsuyoshi NAKAMURA ,  Ryoko YAMAUCHI ,  Hiroshi KOBAYASHI ,  Tatsuya MORITA ,  Tomomi GENDA

IPC: A61K31/717

CPC classification number: A61K31/717 ,  A23L33/24

Abstract: A nutrient composition, a lipid metabolism-improving agent, and prophylactic and/or therapeutic agents typically for inflammatory bowel diseases, immune disorders, cancers, non-alcoholic steatohepatitis, obesity, diabetes, and hypercholesterolemia each contain a cellulose acetate having a total degree of acetyl substitution of 0.4 to 1.1. The cellulose acetate may be one having a compositional distribution index (CDI) of 2.0 or less, where the CDI is defined by the formula: CDI=(Measured value of half height width of chemical composition)/(Theoretical value of half height width of chemical composition) where the measured value of half height width of chemical composition represents a half height width of chemical composition determined by HPLC analysis of a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample), and the theoretical value of half height width of chemical composition=2.35482√{square root over (3*DPw*(DS/3)*(1−DS/3))}/DPw  [Math. 1] where DS is the total degree of acetyl substitution; and DPw is a weight-average degree of polymerization determined by a GPC-light scattering method using a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample).

公开(公告)号：US20190151349A1

公开(公告)日：2019-05-23

申请号：US16258224

申请日：2019-01-25

Applicant: DAICEL CORPORATION

Inventor： Shu SHIMAMOTO ,  Toshikazu NAKAMURA ,  Shizuka UKITA ,  Tsuyoshi NAKAMURA ,  Ryoko YAMAUCHI ,  Hiroshi KOBAYASHI

IPC: A61K31/717 ,  A23L33/24 ,  A23K50/40 ,  A61K45/06 ,  A23K20/163 ,  A23K50/30 ,  A23K50/75 ,  A23K50/10

Abstract: A nutrient composition contains a cellulose acetate having a total degree of acetyl substitution of 0.4 to 1.1. The cellulose acetate may have a compositional distribution index (CDI) of 2.0 or less, where the CDI is specified by the formula: CDI=(Measured value of half height width of chemical composition)/(Theoretical value of half height width of chemical composition) where the measured value of half height width of chemical composition represents the half height width of chemical composition determined by HPLC analysis of a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample); and [Math. 1] the theoretical value of half height width of chemical composition =2. 35482√{square root over (3*DPw*(DS/3)*(1−DS/3))}/DPw where DS is the total degree of acetyl substitution; and DPw is a weight-average degree of polymerization determined by a GPC-light scattering method using a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample).

公开(公告)号：US20160317568A1

公开(公告)日：2016-11-03

申请号：US15106095

申请日：2014-03-24

Applicant: DAICEL CORPORATION

Inventor： Shu SHIMAMOTO ,  Toshikazu NAKAMURA ,  Shizuka UKITA ,  Tsuyoshi NAKAMURA ,  Ryoko YAMAUCHI ,  Hiroshi KOBAYASHI

IPC: A61K31/717 ,  A23L33/24 ,  A23K50/40 ,  A23K20/163 ,  A23K50/75

CPC classification number: A61K31/717 ,  A23K20/163 ,  A23K50/10 ,  A23K50/30 ,  A23K50/40 ,  A23K50/75 ,  A23L33/24 ,  A23V2002/00 ,  A61K45/06 ,  A61K2300/00

Abstract: A nutrient composition contains a cellulose acetate having a total degree of acetyl substitution of 0.4 to 1.1. The cellulose acetate may have a compositional distribution index (CDI) of 2.0 or less, where the CDI is specified by the formula: CDI=(Measured value of half height width of chemical composition)/(Theoretical value of half height width of chemical composition) where the measured value of half height width of chemical composition represents the half height width of chemical composition determined by HPLC analysis of a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample); and the theoretical value of half height width of chemical composition=2.35482√{square root over (3*DPw*(DS/3)*(1−DS/3))}/DPw  [Math. 1] where DS is the total degree of acetyl substitution; and DPw is a weight-average degree of polymerization determined by a GPC-light scattering method using a cellulose acetate propionate prepared by propionylating all residual hydroxy groups of the cellulose acetate (sample).

Abstract translation: 其中DS是乙酰基取代的总量; DPw是通过使用通过丙酰化乙酸纤维素（样品）的所有残留羟基制备的丙酸纤维素的GPC-光散射法测定的重均聚合度。